Cost Effectiveness of Simvastatin Treatment to Lower Cholesterol Levels in Patients with Coronary Heart Disease
| العنوان: | Cost Effectiveness of Simvastatin Treatment to Lower Cholesterol Levels in Patients with Coronary Heart Disease |
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| المؤلفون: | Terje R. Pedersen, Anders G. Olsson, Magnus Johannesson, John Kjekshus, Bengt Jönsson, Hans Wedel |
| المصدر: | New England Journal of Medicine. 336:332-336 |
| بيانات النشر: | Massachusetts Medical Society, 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | medicine.medical_specialty, Cost effectiveness, Vascular disease, Cholesterol, business.industry, General Medicine, medicine.disease, Surgery, Angina, Indirect costs, chemistry.chemical_compound, chemistry, Simvastatin, Internal medicine, medicine, Life expectancy, lipids (amino acids, peptides, and proteins), Myocardial infarction, business, medicine.drug |
| الوصف: | Background The Scandinavian Simvastatin Survival Study (4S) showed that lowering cholesterol levels with simvastatin reduces mortality and morbidity in patients with angina pectoris or previous acute myocardial infarction. Before the widespread use of cholesterol-lowering drugs in such patients is recommended, its cost effectiveness should be demonstrated. We estimated the cost effectiveness of simvastatin treatment to lower cholesterol levels in relation to the age, sex, and cholesterol level before treatment of patients with coronary heart disease. Methods We estimated the cost per year of life gained with simvastatin therapy. To model the increased life expectancy, hazard functions from 4S were used. The costs studied included those of the intervention and the direct and indirect costs associated with morbidity from coronary causes. We prepared separate estimates for men and women at various ages (from 35 to 70 years) and total cholesterol levels before treatment (213 to 309 mg per deciliter). Results ... |
| تدمد: | 1533-4406 0028-4793 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::91d1860ed32762bb4b0eb9daf2bea38eTest https://doi.org/10.1056/nejm199701303360503Test |
| رقم الانضمام: | edsair.doi...........91d1860ed32762bb4b0eb9daf2bea38e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15334406 00284793 |
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