التفاصيل البيبلوغرافية
| العنوان: |
Molecular and Biochemical Parameters Related to Plasma Mannose Levels in Coronary Artery Disease among Nondiabetic Patients |
| المؤلفون: |
Idris Arslan, Aylin Köseler, Ismail Dogu Kilic, Ramazan Sabirli, Oguz Kilic, Ali Zeytunluoglu |
| بيانات النشر: |
Mary Ann Liebert Inc., 2020. |
| سنة النشر: |
2020 |
| مصطلحات موضوعية: |
0301 basic medicine, Blood Glucose, Male, obesity, Turkey, medicine.medical_treatment, Myocardial Infarction, Mannose, insulin blood level, Coronary Artery Disease, Coronary artery disease, Phosphotransferase, chemistry.chemical_compound, Plasma, 0302 clinical medicine, Risk Factors, Hexokinase, cardiac patient, diabetic patient, Gene expression, middle aged, glucose, Genetics (clinical), Glucose Transporter Type 1, Glucose Transporter Type 4, mannose phosphate isomerase, Incidence (epidemiology), adult, General Medicine, Middle Aged, hexokinase 2, hexokinase 1, unclassified drug, female, 030220 oncology & carcinogenesis, Female, coronary artery disease, cardiovascular risk, medicine.medical_specialty, insulin, hypertension, heart infarction, Article, 03 medical and health sciences, angina pectoris, male, Internal medicine, glucose transporter 1, plasma mannose level, glucose transporter 4, medicine, Humans, controlled study, cardiovascular diseases, human, phosphotransferase, Aged, coronary vascular disease (CAD), business.industry, Mannose phosphate isomerase, Insulin, mannose, aging, nondiabetic, medicine.disease, Obesity, major clinical study, 030104 developmental biology, Endocrinology, chemistry, gene expression, incidence, hyperglycemia, business, Biomarkers |
| الوصف: |
Aims: Nondiabetic patients were studied to determine whether modest elevations in plasma mannose may be associated with a greater incidence of coronary artery disease (CAD). Materials and Methods: Plasma insulin, mannose, glucose, hexokinase 1-2, GLUT1-GLUT4 levels, and serum mannose phosphate isomerase enzyme levels were evaluated with respect to subsequent CAD using records from 120 nondiabetic CAD patients and 120 healthy volunteers. CAD was identified from myocardial infarction and new diagnoses of angina. Results: Of 120 nondiabetic CAD patients studied, their plasma GLUT4 and HK1 levels were significantly lower than those of the control group. In addition, a significant increase in plasma mannose levels was found in the patient group compared to the control group. Conclusion: Our findings showed that elevated baseline mannose levels in plasma are associated with an increased risk of CAD over time. © Copyright 2020, Mary Ann Liebert, Inc., publishers 2020. |
| اللغة: |
English |
| الوصول الحر: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5cdd7ecf6283e7bd2fdb7d5e7f9ba4Test |
| حقوق: |
CLOSED |
| رقم الانضمام: |
edsair.doi.dedup.....7a5cdd7ecf6283e7bd2fdb7d5e7f9ba4 |
| قاعدة البيانات: |
OpenAIRE |
