Fulminant Type 1 Diabetes Mellitus: A Study of Nine Cases
| العنوان: | Fulminant Type 1 Diabetes Mellitus: A Study of Nine Cases |
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| المؤلفون: | Kok-Onn Lee, Li-Yuan Fu, Xiaofei Su, Lei Ye, Rui Sun, Huiqin Li, Xiao-hua Xu, Jianhua Ma, Jin-dan Wu |
| المصدر: | Diabetes Technology & Therapeutics. 14:325-329 |
| بيانات النشر: | Mary Ann Liebert Inc, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Blood Glucose, Male, China, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Fulminant, Diabetic Ketoacidosis, Young Adult, chemistry.chemical_compound, Endocrinology, Internal medicine, Diabetes mellitus, Prevalence, medicine, Humans, Age of Onset, Young adult, Intensive care medicine, Glycated Hemoglobin, Type 1 diabetes, business.industry, Case-control study, Middle Aged, medicine.disease, Medical Laboratory Technology, Diabetes Mellitus, Type 1, Early Diagnosis, Postprandial, chemistry, Case-Control Studies, Disease Progression, Female, Glycated hemoglobin, Age of onset, business |
| الوصف: | The study aims to explore the prevalence and clinical features of fulminant type 1 diabetes mellitus (F1DM).We analyzed 11,202 patients who were diagnosed having diabetes and admitted to the Department of Endocrinology, Nanjin First Hospital, Nanjin, China, from September 2005 to April 2011. Among 198 patients classified having type 1 diabetes mellitus (T1DM), nine patients were diagnosed having F1DM. Clinical features of F1DM were analyzed and compared with typical T1DM.The prevalence of F1DM was 4.5% (nine of 198 T1DM patients) in this study. F1DM patients had significantly high levels of random blood glucose (40±9 mmol/L). However, glycated hemoglobin (7.1±1.0%) and C-reactive peptide (0.21±0.15 μg/L) at 2 h postprandial were significantly lower in F1DM patients compared with typical T1DM patients. Six of them had flu-like symptoms. Five of them showed gastrointestinal symptoms. Three patients experienced disturbance of consciousness. However, none of these symptoms was found in patients with typical T1DM. A continuous intravenous insulin infusion therapy using a portable pump was given during the acute phase to control hyperglycemia and ketoacidosis. All F1DM patients survived after treatment.In this single hospital-based study, nine Chinese patients met the criteria for diagnosis of F1DM. Although F1DM may be fatal, prompt treatment is required and useful to rescue these patients. |
| تدمد: | 1557-8593 1520-9156 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fb8eeea1ec8926b9a47eab78e5fc76Test https://doi.org/10.1089/dia.2011.0232Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....67fb8eeea1ec8926b9a47eab78e5fc76 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15578593 15209156 |
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