Growth Patterns in Children With Congenital Cytomegalovirus Infection
| العنوان: | Growth Patterns in Children With Congenital Cytomegalovirus Infection |
|---|---|
| المؤلفون: | Claudia Fortuny, Daniel Blázquez-Gamero, Almudena Alonso-Ojembarrena, María M Hawkins, Elisenda Moliner, Isabel Vives-Oñós, Irene Donoso, Alfonso Cañete, Mar Santos, Fernando Baquero-Artigao, Antoni Noguera-Julian, María José Cilleruelo, María Piñeiro, María T Rives, Sara Domínguez-Rodríguez, Jorge Bustamante, Sergio Suárez, José Tomás Ramos, Gema Medina, Elena Colino, Pablo Rojo, M Antoniette Frick, Beatriz Pérez-Seoane, Alfredo Tagarro, Ruth Del Valle, Itziar Sota |
| المصدر: | PEDIATRIC INFECTIOUS DISEASE JOURNAL r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau |
| بيانات النشر: | LIPPINCOTT WILLIAMS & WILKINS, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Microbiology (medical), Male, Pediatrics, medicine.medical_specialty, Birth weight, growth, MEDLINE, Gestational Age, World Health Organization, 03 medical and health sciences, small for gestational age, 0302 clinical medicine, Child Development, 030225 pediatrics, medicine, Birth Weight, Humans, Insuficiencia de crecimiento, 030212 general & internal medicine, cytomegalovirus, catch-up, Anthropometry, business.industry, Pediatría, Body Weight, Infant, Newborn, Gestational age, Infant, Infant, Low Birth Weight, medicine.disease, Body Height, congenital infection, Low birth weight, Infectious Diseases, Multicenter study, Spain, Child, Preschool, Pediatrics, Perinatology and Child Health, Cytomegalovirus Infections, Infant, Small for Gestational Age, Citomegalovirus, Microcephaly, Small for gestational age, Observational study, Female, medicine.symptom, business |
| الوصف: | Background: Congenital cytomegalovirus infection (CMVc) affects 0.7%-6% of recent births. Among its clinical manifestations are low weight and length at birth. Objective: Describe the growth patterns of children with CMVc in their early years. Methods: Observational, multicenter study of patients with CMVc. Anthropometric data were collected during the first 2 years of life and compared with World Health Organization standards. Results: Anthropometric characteristics of 383 children with CMVc were studied, of which 198 (51%) were symptomatic at birth. At birth, 9% were small for gestational age (SGA) in terms of their weight and length and 17% had microcephaly. At 24 ± 3 months, 10% had a weight and length ≤2 SD, and 13% a head circumference ≤2 SD. Of those who were SGA at birth, at 24 ± 3 months >20% remained at ≤2 SD of their weight and length. Conversely, 75% of children with low weight or length at 24 ± 3 had not been SGA at birth. 20% of infants with microcephaly at birth remained with microcephaly, and 10% of those without microcephaly developed it at 24 ± 3 months. The average growth rate in length and weight was normal. Patients who were symptomatic at birth, premature and with motor and neurocognitive impairment had a significantly higher risk of low weight and length at 24 ± 3 months. Conclusion: Around 10% of children with CMVc are at ≤2 SD in weight, length and head circumference at 24 ± 3 months. The lack of adequate growth is associated with symptoms at birth, prematurity and motor and neurocognitive impairment. Growth impairment could be incorporated into the symptomatic spectrum of CMVc. Sin financiación 3.164 JCR (2020) Q3, 56/92 Infectious Diseases 1.269 SJR (2020) Q1, 69/292 Infectious Diseases No data IDR 2019 UEM |
| تدمد: | 0891-3668 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a85c2b1fcc8491728118962135ef0b5Test http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=16865Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1a85c2b1fcc8491728118962135ef0b5 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 08913668 |
|---|