دورية أكاديمية
Blood lipids in 75,048 type 2 diabetic patients: a population-based survey from the Swedish National diabetes register
| العنوان: | Blood lipids in 75,048 type 2 diabetic patients: a population-based survey from the Swedish National diabetes register |
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| المؤلفون: | Eriksson, Mats, Zethelius, Bjorn, Eeg-Olofsson, Katarina, Nilsson, Peter, Gudbjornsdottir, Soffia, Cederholm, Jan, Eliasson, Bjorn |
| المصدر: | European Journal of Cardiovascular Prevention & Rehabilitation; 18(1), pp 97-105 (2011) ; ISSN: 1741-8275 |
| بيانات النشر: | Lippincott Williams & Wilkins |
| سنة النشر: | 2011 |
| المجموعة: | Lund University Publications (LUP) |
| مصطلحات موضوعية: | Other Clinical Medicine, Blood lipids, cholesterol, epidemiology, high-density, lipoprotein-cholesterol, low-density lipoprotein-cholesterol, triglycerides, type 2 diabetes |
| الوصف: | Background: Type 2 diabetes and diabetic dyslipidemia are high-risk conditions for cardiovascular disease. However, the description of the distribution of blood lipids in diabetic patients has not been based on population-based surveys. The aim of this study was to describe diabetic dyslipidemia in a large unselected sample of patients from the Swedish National Diabetes Register. Methods: Blood lipid profiles and clinical characteristics in 75,048 type 2 diabetic patients (57% men) were studied. Results: Pronounced hypertriglyceridemia (triglycerides >4.0mmol/l) was seen in 3.4% of the patients. Total cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C) and non-HDL-C were generally higher, and LDL-C/HDL-C and Non-HDL-C/HDL-C ratios were lower in women. Mean TC, LDL-C as well as HDL-C values were lower in patients treated with lipid-lowering agents, whereas triglycerides was higher than in the untreated patients. In patients not treated with lipid-lowering agents all blood lipids increased in women and decreased in men (except HDL-C) at higher ages. Patients with LDL-C/HDL-C ratio >= 3 were slightly younger, less frequently used lipid-lowering drugs and had not so often a history of coronary heart disease or stroke. Conclusion: The distribution of blood lipids in this large sample of unselected type 2 diabetic patients challenges the previous conception of diabetic dyslipidemia, and calls for new studies to explain the roles of LDL-C and HDL-C as strong cardiovascular risk factors in type 2 diabetes. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | https://lup.lub.lu.se/record/1876170Test; http://dx.doi.org/10.1097/HJR.0b013e32833ba61eTest; wos:000287780400011; scopus:79955707469 |
| DOI: | 10.1097/HJR.0b013e32833ba61e |
| الإتاحة: | https://doi.org/10.1097/HJR.0b013e32833ba61eTest https://lup.lub.lu.se/record/1876170Test |
| رقم الانضمام: | edsbas.7D2CDBF6 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1097/HJR.0b013e32833ba61e |
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