NONMALARIAL ACUTE UNDIFFERENTIATED FEVER- DIAGNOSTIC UNCERTAINTY AND OVERTREATMENT WITH ANTIMALARIALS
| العنوان: | NONMALARIAL ACUTE UNDIFFERENTIATED FEVER- DIAGNOSTIC UNCERTAINTY AND OVERTREATMENT WITH ANTIMALARIALS |
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| المؤلفون: | Subhash Chand Jain, Madhuri Meena, Rameshwar Prasad Gupta, Uma Shankar Shukla |
| المصدر: | Journal of Evidence Based Medicine and Healthcare, Vol 3, Iss 97, Pp 5340-5343 (2016) |
| بيانات النشر: | Level Up Business Center, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.medical_specialty, Nonmalarial Acute Undifferentiated Fever (NMAUF), business.industry, lcsh:R5-130.5, parasitic diseases, medicine, RDT (Rapid Diagnostic Test), Anti-Malarial Drugs, Intensive care medicine, business, lcsh:General works, Malaria |
| الوصف: | BACKGROUND Nonmalarial Acute Undifferentiated Fever (NMAUF) means a febrile illness with no indication of an organ-specific disease after exclusion of diagnosis of malaria. Empirical treatment of NMAUFs with antimalarial drugs continues despite the availability of highly specific Rapid Diagnostic Tests (RDTs) for malaria. MATERIALS AND METHODS This retrospective study was conducted in patients with fever admitted to Jhalawar Medical College Hospital, Jhalawar, Rajasthan. We categorised patients with NMAUF into different clinical syndromes and determined the pattern of antimalarial use. 1523 adult patients were investigated for malaria, 1355 (88.97%) of them had NMAUF. RESULTS Having negative tests for malaria, many patients (38.16%, 95% CI (31.0-39.5)) received antimalarial drugs. These results suggest a need to improve empiric treatment for NMAUF. CONCLUSION Most of the hospitalised patients with acute febrile illness do not have malaria, but received antimalarial therapy. There is a need to develop rapid antigen based tests, detection of pathogens responsible for NMAUFs, so that definitive causative organisms can be identified. |
| اللغة: | English |
| تدمد: | 2349-2570 2349-2562 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea61ac48a8f521b0afc8f50fa35cba7Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....9ea61ac48a8f521b0afc8f50fa35cba7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23492570 23492562 |
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