NY-ESO-1 expression in sarcomas
| العنوان: | NY-ESO-1 expression in sarcomas |
|---|---|
| المؤلفون: | Lai, Jin-Ping, Rosenberg, Avi Z., Miettinen, Markku M., Lee, Chyi-Chia R. |
| المصدر: | Oncoimmunology |
| بيانات النشر: | Landes Bioscience, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | diagnostic marker, melanoma, NY-ESO-1, therapeutic target, T-cell receptor, clinical trial, immunotherapy, cancer-testis antigen, sarcomas, synovial sarcoma, Author's View |
| الوصف: | NY-ESO-1 (CTAG 1B) is highly expressed in the majority of synovial sarcomas and myxoid/round cell liposarcomas as well as in a subset of melanomas, but only rarely in other mesenchymal tumors. This points to a potential for using NY-ESO-1 in the differential diagnosis of these lesions. Furthermore, promising results have been obtained in clinical trials testing NY-ESO-1-targeted immunotherapy in subsets of melanoma and synovial sarcoma patients. |
| اللغة: | English |
| تدمد: | 2162-402X 2162-4011 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=pmid________::b9ed128524aad7dde9ebf44469815000Test http://europepmc.org/articles/PMC3518519Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.pmid..........b9ed128524aad7dde9ebf44469815000 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2162402X 21624011 |
|---|