Long-term follow-up of hepatic ultrasound findings in subjects with magnetic resonance imaging defined hepatic steatosis following clinical islet transplantation
| العنوان: | Long-term follow-up of hepatic ultrasound findings in subjects with magnetic resonance imaging defined hepatic steatosis following clinical islet transplantation |
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| المؤلفون: | Jackson, Stephanie, Mager, Diana R., Bhargava, Ravi, Ackerman, Thomas, Imes, Sharleen, Hubert, Grace, Koh, Angela, Shapiro, A.M. James, Senior, Peter A. |
| المصدر: | Islets |
| بيانات النشر: | Landes Bioscience, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | Adult, Male, type 1 diabetes, Remission, Spontaneous, Short Report, Islets of Langerhans Transplantation, Alberta, Cohort Studies, Young Adult, Recurrence, Risk Factors, Prevalence, magnetic resonance imaging, Humans, Longitudinal Studies, Retrospective Studies, Ultrasonography, ultrasound, hepatic steatosis, Graft Survival, clinical islet transplantation, Middle Aged, Fatty Liver, Diabetes Mellitus, Type 1, Liver, Case-Control Studies, Disease Progression, Female |
| الوصف: | Hepatic steatosis is one complication patients may experience following clinical islet transplantation (CIT), yet the cause and consequences of this are poorly understood. The purpose of this case-control study was to examine the relationship between hepatic steatosis, metabolic parameters and graft function in an Albertan cohort of CIT recipients. Hepatic steatosis was detected by magnetic resonance imaging (MRI) in n = 10 cases age-matched with n=10 MRI-negative controls. Progression/regression of steatosis was determined by ultrasound (US) in cases. Hepatic steatosis first appeared 2.8 ± 2.2 (mean ± SD) years post-CIT, and lasted approximately 4.6 ± 2.0 years. In five cases steatosis resolved, with recurrence in two cases during the follow-up period (8.5 ± 3.2 years). No evidence of CIT causing deleterious effects on long-term liver function or graft outcome was observed. |
| اللغة: | English |
| تدمد: | 1938-2022 1938-2014 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=pmid________::0db0d9aa6a38e49ed6bbe9014b8c55feTest http://europepmc.org/articles/PMC3662378Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.pmid..........0db0d9aa6a38e49ed6bbe9014b8c55fe |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19382022 19382014 |
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