التفاصيل البيبلوغرافية
| العنوان: |
12-h pretreatment with methylprednisolone versus placebo for prevention of postextubation laryngeal oedema: a randomised double-blind trial. |
| المؤلفون: |
François, Bruno1,2, Bellissant, Eric3, Gissot, Valérie4, Desachy, Arnaud5, Normand, Sandrine1, Boulain, Thierry6, Brenet, Olivier7, Preux, Pierre-Marie8, Vignon, Philippe1,2 philippe.vignon@unilim.fr |
| المصدر: |
Lancet. 3/31/2007, Vol. 369 Issue 9567, p1083-1089. 7p. 1 Diagram, 5 Charts. |
| مصطلحات موضوعية: |
*TRACHEA intubation, *INTUBATION, *ADRENOCORTICAL hormones, *ARTIFICIAL respiration, *CRITICAL care medicine, *RANDOMIZED controlled trials, *EDEMA prevention |
| مستخلص: |
The article presents a randomized controlled trial that examined the use of the corticosteroid methylprednisolone to prevent laryngeal edema in patients after they had a tracheal intubation tube removed. Patients in the study were recruited from the intensive care units of hospitals and were ventilated for more than thirty-six hours. The authors found that intravenous administration of methylprednisolone before extubation reduced the occurrence of post-extubation laryngeal edema and suggest that the pretreatment with methylprednisolone be considered for patients prior to a planned extubation. |
| قاعدة البيانات: |
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