دورية أكاديمية
Prognosis of Acute Intracranial Atherosclerosis-Related Occlusion after Endovascular Treatment
| العنوان: | Prognosis of Acute Intracranial Atherosclerosis-Related Occlusion after Endovascular Treatment |
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| المؤلفون: | Jin Soo Lee, Seong-Joon Lee, Joon Sang Yoo, Jeong-Ho Hong, Chang-Hyun Kim, Yong-Won Kim, Dong-Hun Kang, Yong-Sun Kim, Ji Man Hong, Jin Wook Choi, Bruce Ovbiagele, Andrew M. Demchuk, Sung-Il Sohn, Yang-Ha Hwang |
| المصدر: | Journal of Stroke, Vol 20, Iss 3, Pp 394-403 (2018) |
| بيانات النشر: | Korean Stroke Society |
| سنة النشر: | 2018 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | cerebral infarction, atherosclerosis, embolism, thrombectomy, reperfusion, treatment outcome, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: | Background and Purpose Little is known about prognosis after endovascular therapy (EVT) for acute large artery occlusion (LAO) caused by underlying intracranial atherosclerotic stenosis (ICAS). Therefore, we investigated the prognosis following EVT according to the underlying etiology of LAO. Methods Patients from the Acute Stroke due to Intracranial Atherosclerotic occlusion and Neurointervention-Korean Retrospective (ASIAN KR) registry (n=720) were included if their occlusion was in the intracranial anterior circulation and their onset-to-puncture time was <24 hours. Occlusion was classified according to etiology as follows: no significant stenosis after recanalization (Embolic group), and fixed significant focal stenosis in the occlusion site with flow impairment or re-occlusion observed during EVT (ICAS group). Patients were excluded when significant extracranial carotid lesions existed, and when the intracranial occlusion was intractable to EVT so that the etiology was undetermined. The effect of angiographic etiologic classification on outcomes was evaluated using multivariable analysis that was adjusted for potential confounders. Results Among eligible patients (n=520), 421 and 99 were classified in the Embolic and ICAS groups, respectively. Patients in the Embolic and ICAS groups had similar successful reperfusion rates with EVT (79.6% vs. 76.8%, P=0.537) and 3-month functional independence (54.5% vs. 45.5%, P=0.104). In multivariable analysis, ICAS-related occlusion (odds ratio, 0.495; 95% confidence interval, 0.269 to 0.913; P=0.024) showed poorer 3-month functional independence compared to embolic occlusion. Conclusions After EVT, patients with acute ICAS-related occlusion have relatively poor functional outcomes compared to those with embolic occlusion. Novel strategies need to be developed to improve EVT outcomes for ICAS occlusion. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2287-6391 2287-6405 |
| العلاقة: | http://www.j-stroke.org/upload/pdf/jos-2018-01627.pdfTest; https://doaj.org/toc/2287-6391Test; https://doaj.org/toc/2287-6405Test; https://doaj.org/article/19e41d08816340419f1f58c94423a3ddTest |
| DOI: | 10.5853/jos.2018.01627 |
| الإتاحة: | https://doi.org/10.5853/jos.2018.01627Test https://doaj.org/article/19e41d08816340419f1f58c94423a3ddTest |
| رقم الانضمام: | edsbas.4E1A2215 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 22876391 22876405 |
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| DOI: | 10.5853/jos.2018.01627 |