التفاصيل البيبلوغرافية
| العنوان: |
Diagnostic yield of sonicate culture in the periprosthetic joint infection in Korea : fungal cultures should not be routinely obtained for diagnostic work-up. |
| المؤلفون: |
Yoonjung Lee, Min-Ji Kim, Se-Ra Kim, Tae-Hoon Oh, Seong Eun Kim, Uh Jin Kim, Seung-Ji Kang, Sook-In Jung, Kyung-Hwa Park |
| المصدر: |
Infection & Chemotherapy; 2022 Supplement, Vol. 54, p378-378, 1p |
| مصطلحات موضوعية: |
JOINT infections, FUNGAL cultures, MYCOSES, ARTIFICIAL joints, BACTERIAL cultures, ORTHOPEDIC surgery |
| مصطلحات جغرافية: |
SOUTH Korea |
| مستخلص: |
배경: Fungal and mycobacterial periprosthetic joint infection (PJI) are rare events. However, clinicians routinely perform multiple samples of fungal and mycobacterial cultures, as well as bacterial cultures, We recently have used sonicate culture to identify causative pathogens by disrupting biofilms since 2017. We compared the results of a culture method using sonication with those yielded by the conventional tissue culture method, for patients with suspected PJIs and we examined the utility of routine fungal cultures in PJI diagnosis. 방법: We performed a retrospective review of patients who visited our clinic under suspicion of orthopedic-related infection from 2017 to 2021 and underwent surgery to remove the prosthesis component. A modified clinical criterion consisting of the presence of sinus ducts, histological findings and purulence around the prostheses was used to compare the efficacy of micro-biological studies. We also reviewed the number of fungal samples performed and culture positivity rates. 결과: There were 175 patients with suspected PJI within the study period. Sonicate fluid cultures were positive in 101 patients (57.7%). For periprosthetic tissue cultures, 93 of 175 (53.1%) were positive. Sonicate fluid culture showed higher sensitivity and lower specificity compared to periprosthetic tissue culture (58.43 vs. 54.22% and 55.56 and 66.67, respectively). In particular, pathogen identification was possible in 13 cases through combining culture methods. In addition, a total of 613 fungal cultures were performed in 175 cases, of which 10 cases were cultured in both bacterial and fungal cultures. 결론: Sonicate fluid culture aided in pathogen identification and appropriate antimicrobial treatment against the causative organisms in chronic indolent infection. Moreover, all 10 cases of proven fungal prosthetic joint infection were cultured in both fungal cultures and conventional bacterial cultures, suggesting that routine fungal cultures should not be performed. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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