دورية أكاديمية

DIASTOLIC DYSSYNCHRONY IN ACUTE ST SEGMENT ELEVATION MYOCARDIAL INFARCTION AND RELATIONSHIP WITH FUNCTIONAL RECOVERY OF LEFT VENTRICLE.

التفاصيل البيبلوغرافية
العنوان: DIASTOLIC DYSSYNCHRONY IN ACUTE ST SEGMENT ELEVATION MYOCARDIAL INFARCTION AND RELATIONSHIP WITH FUNCTIONAL RECOVERY OF LEFT VENTRICLE.
المؤلفون: TURAN, BURAK, DASLI, TOLGA, ERKOL, AYHAN, ERDEN, ISMAIL, BA$ARAN, YELDA
المصدر: Journal of Cardiovascular Ultrasound; Sep2016, Vol. 24 Issue 3, p208-214, 7p
مصطلحات موضوعية: MYOCARDIAL infarction, LEFT heart ventricle
مستخلص: BACKGROUND: Incidence of diastolic dyssynchrony (DD) and its impact on functional recovery of left ventricle (LV) after ST segment elevation myocardial infarction (STEMI) is not known. METHODS: Consecutive patients with STEMI who underwent successful revascularization were prospectively enrolled. Echcxrardiography with tissue Doppler imaging was performed within 48 hours of admission and at 6 months. LV end-diastolic volume index (EDVI),end-systolic volume index (ESVI), ejection fraction (EF), and left atrial volume index (LAVI) were calculated. Diastolic delay was calculated from onset of QRS complex to peak of E wave in tissue Doppler image and presented as maximal temporal difference between peak early diastolic velocity of 6 basal segments of LV (TeDiff). Study patients were compared with demographically matched control group. RESULTS: Forty eight consecutive patients (55 ± 10 years, 88% male) and 24 controls (56 ± 6 years, 88% male) were included. TeDiff was higher in STEMI than in controls (35.9 ± 19.9 ms vs. 26.3 ± 6.8 ms, J? = 0.025). Presence of DD was higher in STEMI than controls (58% vs. 33%, P = 0.046) according to calculated cut-off value (> 29 ms). There was no correlation between TeDiff and change in EDVI, ESVI, and LAVI at 6 months, however TeDiff and change in EF at 6 months was positively correlated (r = 0328, p = 0.023). Patients with baseline DD experienced remodeling less frequently compared to patients without baseline DD (11% vs. U p = 0.040) during follow-up. CONCLUSION: STEMI disrupts diastolic synchronicity of LV. However, DD during acute phase of STEMI is associated with better recovery of LV thereafter. This suggests that DD is associated with peri-infarct stunned myocardium that is salvaged with primary intervention as well as infarct size. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:19754612
DOI:10.4250/jcu.2016.24.3.208