دورية أكاديمية

Tracheal intubation with rocuronium using a 'modified timing principle'

التفاصيل البيبلوغرافية
العنوان: Tracheal intubation with rocuronium using a 'modified timing principle'
المؤلفون: Min A Kwon, Jaegyok Song, Ju-Ri Kim
المصدر: Korean Journal of Anesthesiology, Vol 64, Iss 3, Pp 218-222 (2013)
بيانات النشر: Korean Society of Anesthesiologists
سنة النشر: 2013
المجموعة: Directory of Open Access Journals: DOAJ Articles
مصطلحات موضوعية: intratracheal, intubation, rocuronium, succinylcholine, Anesthesiology, RD78.3-87.3
الوصف: BackgroundRapid sequence induction (RSI) is indicated in various situations. Succinylcholine has been the muscle relaxant of choice for RSI, and rocuronium has become an alternative medicine for patients who cannot be administered succinylcholine for various reasons. Although rocuronium has the most rapid onset time among non-depolarizing muscle relaxants, the standard dose of rocuronium (0.6 mg/kg) takes 60 seconds to achieve appropriate muscle relaxation. We evaluated intubating conditions using the "modified timing principle" with rocuronium and succinylcholine.MethodsIn this prospective controlled blinded study, all patients received 1.5 µg/kg fentanyl intravenously with preoxygenation for 2 minutes and were randomized to receive 0.6 mg/kg rocuronium followed by 1.5 mg/kg propofol or 1.5 mg/kg propofol and 1.5 mg/kg succinylcholine. The rocuronium group was intubated just after confirming loss of consciousness, and the succinylcholine group was intubated 1 minute after injecting succinylcholine. Intubation condition, timing of events, and complications were recorded.ResultsAll patients were successfully intubated in both groups. Apnea time of the rocuronium group (38.5 seconds) was significantly shorter than that in the succinylcholine group (100.7 seconds). No significant differences were observed in loss of consciousness time or intubation time. The succinylcholine group tended to show better intubation conditions, but no significant difference was observed. None of the patients complained awareness of the intubation procedure or had respiratory difficulty during a postoperative interview.ConclusionsThe modified RSI with rocuronium showed shorter intubation sequence, acceptable intubation conditions, and a similar level of complications compared to those of conventional RSI with succinylcholine.
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 2005-6419
2005-7563
العلاقة: http://ekja.org/upload/pdf/kjae-64-218.pdfTest; https://doaj.org/toc/2005-6419Test; https://doaj.org/toc/2005-7563Test; https://doaj.org/article/05eb1c0281864d059107508d3b02009aTest
DOI: 10.4097/kjae.2013.64.3.218
الإتاحة: https://doi.org/10.4097/kjae.2013.64.3.218Test
https://doaj.org/article/05eb1c0281864d059107508d3b02009aTest
رقم الانضمام: edsbas.659201AE
قاعدة البيانات: BASE
الوصف
تدمد:20056419
20057563
DOI:10.4097/kjae.2013.64.3.218