Clinical Outcome in Male Patients With Detrusor Overactivity With Impaired Contractility
| العنوان: | Clinical Outcome in Male Patients With Detrusor Overactivity With Impaired Contractility |
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| المؤلفون: | Shuo Liu, Vincent Tse, Lewis Chan |
| المصدر: | International Neurourology Journal International Neurourology Journal, Vol 18, Iss 3, Pp 133-137 (2014) |
| بيانات النشر: | Korean Continence Society, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Adrenergic alpha-antagonists, medicine.medical_specialty, Urology, Urodynamic studies, lcsh:RC870-923, urologic and male genital diseases, Contractility, Overactive urinary bladder, Cholinergic antagonists, Lower urinary tract symptoms, Medicine, Adrenergic alpha-Antagonists, Gynecology, urogenital system, business.industry, lcsh:Diseases of the genitourinary system. Urology, medicine.disease, female genital diseases and pregnancy complications, Cholinergic Antagonists, Urodynamics, Neurology, Male patient, Original Article, Neurology (clinical), business |
| الوصف: | Purpose To review the clinical outcomes of patients with voiding dysfunction who have detrusor overactivity with impaired contractility (DOIC) diagnosed with urodynamic studies. Methods Urodynamic reports from 2005 to 2009 were reviewed, and 54 male patients had findings consistent with DOIC. Patients with acontractile or neuropathic bladders were excluded. Clinical outcomes were obtained from patient records. Results Of 54 men, 8 presented with voiding symptoms, 17 had storage symptoms, and 29 had mixed symptoms. Twenty-two had a previous transurethral resection of the prostate. The median follow-up was 12 months. Four patients received no intervention. Two patients were taught intermittent self-catheterization. Five patients underwent surgery to reduce outlet resistance and all reported improvement. Forty-three patients were started on pharmacotherapy; symptomatic improvement was reported by 9 of 16 patients commenced on anticholinergics alone, 6 of 16 on alpha-blockers alone, and 4 of 5 treated with a combination of alpha-blockers and anticholinergics. Eleven patients experienced no difference on pharmacotherapy and 2 reported deterioration. One patient developed acute urinary retention (18 months after commencing treatment with alpha-blockers). No patient had urosepsis. Conclusions Anticholinergics and alpha-blockers appear to be safe in patients with DOIC. The risk of urinary retention and sepsis is low. The majority of patients report symptomatic benefit from either drugs or surgical treatment. |
| تدمد: | 2093-6931 2093-4777 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e16616a478870043d46849a54c782b2Test https://doi.org/10.5213/inj.2014.18.3.133Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....5e16616a478870043d46849a54c782b2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20936931 20934777 |
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