Optical coherence tomography angiography in retinal diseases
| العنوان: | Optical coherence tomography angiography in retinal diseases |
|---|---|
| المؤلفون: | Kakarla V. Chalam, Kumar Sambhav |
| المصدر: | Journal of Ophthalmic & Vision Research, Vol 11, Iss 1, Pp 84-92 (2016) Journal of Ophthalmic & Vision Research |
| بيانات النشر: | Knowledge E, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.medical_specialty, genetic structures, Review Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, lcsh:Ophthalmology, Ophthalmology, Medicine, Optical Coherence Tomography Angiography (OCTA), Retinal Vascular Occlusion, Diabetic Retinopathy, medicine.diagnostic_test, business.industry, Retinal, Blood flow, Diabetic retinopathy, Macular degeneration, medicine.disease, Fluorescein angiography, Age Related Macular Degeneration, Choroidal Neovascularization, eye diseases, Split-spectrum Amplitude Decorrelation Angiography (SSADA), Choroidal neovascularization, chemistry, lcsh:RE1-994, Angiography, 030221 ophthalmology & optometry, Optometry, medicine.symptom, business, 030217 neurology & neurosurgery |
| الوصف: | Optical coherence tomography angiography (OCTA) is a new, non-invasive imaging system that generates volumetric data of retinal and choroidal layers. It has the ability to show both structural and blood flow information. Split-spectrum amplitude-decorrelation angiography (SSADA) algorithm (a vital component of OCTA software) helps to decrease the signal to noise ratio of flow detection thus enhancing visualization of retinal vasculature using motion contrast. Published studies describe potential efficacy for OCTA in the evaluation of common ophthalmologic diseases such as diabetic retinopathy, age related macular degeneration (AMD), retinal vascular occlusions and sickle cell disease. OCTA provides a detailed view of the retinal vasculature, which allows accurate delineation of microvascular abnormalities in diabetic eyes and vascular occlusions. It helps quantify vascular compromise depending upon the severity of diabetic retinopathy. OCTA can also elucidate the presence of choroidal neovascularization (CNV) in wet AMD. In this paper, we review the knowledge, available in English language publications regarding OCTA, and compare it with the conventional angiographic standard, fluorescein angiography (FA). Finally, we summarize its potential applications to retinal vascular diseases. Its current limitations include a relatively small field of view, inability to show leakage, and tendency for image artifacts. Further larger studies will define OCTA's utility in clinical settings and establish if the technology may offer a non-invasive option of visualizing the retinal vasculature, enabling us to decrease morbidity through early detection and intervention in retinal diseases. |
| اللغة: | English |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8684341e4e322282128ff95911e3c4b3Test http://www.jovr.org/article.asp?issn=2008-322X;year=2016;volume=11;issue=1;spage=84;epage=92;aulast=ChalamTest |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8684341e4e322282128ff95911e3c4b3 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |