التفاصيل البيبلوغرافية
| العنوان: |
Expression of synapsin I gene in primary cultures of differentiating rat cortical neurons |
| المؤلفون: |
A. Cestelli, Massimo Coppolino, Maria Scaturro, Giovanni Savettieri, Daniele Castiglia, Maria Monte, Italia Di Liegro, Giuseppe Salemi, Tommaso Nastasi |
| المساهمون: |
Di Liegro, I., Savettieri, G., Coppolino, M., Scaturro, M., Monte, M., Nastasi, T., Salemi, G., Castiglia, D., Cestelli, A. |
| بيانات النشر: |
Kluwer Academic Publishers-Plenum Publishers, 1995. |
| سنة النشر: |
1995 |
| مصطلحات موضوعية: |
Gene isoform, medicine.medical_specialty, Synapsin I, Time Factors, Transcription, Genetic, Blotting, Western, synapsin I, Gene Expression, Biology, Biochemistry, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Fetus, Internal medicine, Settore BIO/10 - Biochimica, Gene expression, medicine, Animals, RNA, Messenger, Neurotransmitter, Cells, Cultured, Cell Nucleus, Cerebral Cortex, Neurons, Messenger RNA, Neuroscience (all), Cell Differentiation, General Medicine, Synapsin, Blotting, Northern, Synapsins, thyroid hormone, Rats, Cell biology, Kinetics, medicine.anatomical_structure, Endocrinology, nervous system, chemistry, Neuronal differentiation, Synaptic plasticity, Triiodothyronine, Settore MED/26 - Neurologia, Neuron |
| الوصف: |
Synapsin I is a neuron-specific protein which is present in two isoforms, Ia and Ib. In the last few years this protein has been demonstrated to play a central role in the regulation of neurotransmitter release and synaptic plasticity. In this paper the developmental expression of this protein has been investigated in primary neuronal cultures from fetal rat brain cortices. The presence of thyroid hormone in the culture medium stimulates an early expression of the protein without exerting any effect at the level of mRNA transcription and accumulation. These observations implicate a T3-dependent regulation of this neuron-specific gene at the level of mRNA translation. © 1995 Plenum Publishing Corporation. |
| اللغة: |
English |
| الوصول الحر: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f13d2071cb0f7062f0b81f7e9bb4ae7Test
http://hdl.handle.net/10447/207617Test |
| حقوق: |
CLOSED |
| رقم الانضمام: |
edsair.doi.dedup.....4f13d2071cb0f7062f0b81f7e9bb4ae7 |
| قاعدة البيانات: |
OpenAIRE |
