دورية أكاديمية

Aortic Isthmus Flow Recording Predicts the Outcome of the Recipient Twin after Laser Coagulation in Twin-Twin Transfusion Syndrome.

التفاصيل البيبلوغرافية
العنوان: Aortic Isthmus Flow Recording Predicts the Outcome of the Recipient Twin after Laser Coagulation in Twin-Twin Transfusion Syndrome.
المؤلفون: Leduc, France1, Delabaere, amélie1, Gendron, Roxanne1, Fuchs, Florent1, Wavrant, Sandrine1, Raboisson, Marie-Josée1, Fouron, Jean-Claude1, audibert, François1 francois.audibert@umontreal.ca, Delabaere, Amélie (AUTHOR), Raboisson, Marie-Josée (AUTHOR), Audibert, François (AUTHOR)
المصدر: Fetal Diagnosis & Therapy. Aug2018, Vol. 44 Issue 2, p135-141. 7p.
مصطلحات موضوعية: *FETOFETAL transfusion, *LASER coagulation, *FETAL echocardiography, *GESTATIONAL age, *DOPPLER velocimetry, *AORTA physiology, *AORTA, *BLOOD flow measurement, *COMPARATIVE studies, *DOPPLER echocardiography, *FETOSCOPY, *HEMODYNAMICS, *MEDICAL lasers, *RESEARCH methodology, *MEDICAL cooperation, *PERINATAL death, *RESEARCH, *TWINS, *EVALUATION research, *TREATMENT effectiveness, *PREDICTIVE tests, *SURGERY
مستخلص: Introduction: The objective was to assess the prognostic value of the systolic flow through the aortic isthmus in monochorionic pregnancies complicated by twin-twin transfusion syndrome (TTTS) treated by placental laser ablation.Material and Methods: Fetal echocardiography and outcome data of 105 cases of TTTS treated by laser photocoagulation of placental anastomoses were reviewed. Hemodynamic parameters were collected before and after treatment. The isthmic systolic index (ISI) was calculated as the peak systolic velocity/systolic nadir ratio.Results: A total of 105 laser coagulations were studied. Fetal echocardiography pre- and post-laser were available in 68 cases, including 55 with data on aortic isthmic Doppler. Survival rates were 17, 22, and 61% for 0, 1, or 2 twins, respectively. At least 1 twin was delivered alive in 83% of the pregnancies. The mean gestational age at surgery was 21 weeks (range 16-26). Median ISI values were similar for donor and recipient twins, before and after laser ablation (all p > 0.05). A lower recipient ISI before laser was related to early recipient demise within 24 h (p = 0.04).Discussion: A lower ISI before placental laser ablation for TTTS is associated with postoperative demise of the recipient twin. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:10153837
DOI:10.1159/000479736