دورية أكاديمية
Effects of intranasal estradiol treatment on serum lipoprotein(a) and lipids in hysterectomized women
| العنوان: | Effects of intranasal estradiol treatment on serum lipoprotein(a) and lipids in hysterectomized women |
|---|---|
| المؤلفون: | H Kiran, G Kiran, Ekerbiçer, Hasan Çetin, M Kilinc |
| المساهمون: | Kiran, H, Kiran, G, Ekerbicer, HC, Kilinc, M, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Ekerbiçer, Hasan Çetin |
| بيانات النشر: | KARGER |
| سنة النشر: | 2004 |
| الوصف: | The aim of the present study was to evaluate the effects of intranasal estradiol on lipid metabolism and lipoprotein(a)[Lp(a)] levels. A prospective comparative study was designed: 49 hysterectomized, healthy postmenopausal women received intranasal 17beta-estradiol (E-2; 300 mug/day). Blood samples were collected at baseline and at the end of the 3 and 6 months of therapy. After 6 months, the serum levels of total cholesterol, LDL-cholesterol and triglycerides did not show any significant change with intranasal 17beta-E-2 therapy. HDL-cholesterol levels at 3 and 6 months of treatment were significantly increased compared with baseline levels (p=0.031, p=0.000, respectively). There was a significant change in serum Lp(a) levels at the 6th month (p=0.003) but not at the 3rd month (p=0.183) compared with the baseline levels. Further studies are needed to detect whether these changes are significant and permanent or not. Copyright (C) 2004 S. Karger AG, Basel. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0378-7346 |
| العلاقة: | Kiran, H; Kiran, G; Ekerbicer, HC; Kilinc, M; (2004). Effects of intranasal estradiol treatment on serum lipoprotein(a) and lipids in hysterectomized women. , 57, 195-191; https://doi.org/10.1159/000076627Test; https://hdl.handle.net/20.500.12619/66690Test; 57; 191; 195; WOS:000221244900003 |
| DOI: | 10.1159/000076627 |
| الإتاحة: | https://doi.org/20.500.12619/66690Test https://doi.org/10.1159/000076627Test https://hdl.handle.net/20.500.12619/66690Test |
| رقم الانضمام: | edsbas.B99D3F8C |
| قاعدة البيانات: | BASE |
| تدمد: | 03787346 |
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| DOI: | 10.1159/000076627 |