A Review of the Imaging Techniques for Measuring Kidney and Cyst Volume in Establishing Autosomal Dominant Polycystic Kidney Disease Progression
| العنوان: | A Review of the Imaging Techniques for Measuring Kidney and Cyst Volume in Establishing Autosomal Dominant Polycystic Kidney Disease Progression |
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| المؤلفون: | Magistroni R., Corsi C., Martí T., Torra R. |
| المصدر: | AMERICAN JOURNAL OF NEPHROLOGY r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname |
| بيانات النشر: | KARGER, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | kidney, diagnostic imaging, genotype, Review, computer assisted tomography, Predictive Value of Tests, x-ray computed tomography, Image Processing, Computer-Assisted, Humans, human, procedures, nuclear magnetic resonance imaging, end stage renal disease, pathophysiology, Ultrasonography, clinical article, Clinical Trials as Topic, predictive value, literature, echography, imaging, clinical trial (topic), organ size, chronic kidney failure, Polycystic Kidney, Autosomal Dominant, Prognosis, Magnetic Resonance Imaging, image processing, kidney polycystic disease, age, priority journal, tumor volume, disease exacerbation, stereology, Disease Progression, Kidney Failure, Chronic, pathology, measurement accuracy, Tomography, X-Ray Computed |
| الوصف: | Background: Autosomal dominant polycystic kidney disease (ADPKD) is the commonest inherited renal disorder; it is defined by progressive renal cyst formation and subsequent renal enlargement that leads to end-stage renal disease. Until recently, only symptomatic treatments for ADPKD existed. However, therapies that address the underlying pathophysiology of ADPKD are now available and accurate identification of the rate of disease progression is essential. Summary: Published data on the different imaging modalities for measuring kidney and cyst volumes in ADPKD are reviewed. The advantages and drawbacks of the different techniques for calculating kidney volume from renal imaging are also examined, including the use of manual planimetry, stereology, and the ellipsoid equation, as well as the prospect of semi- and fully automatic techniques. The translation of these approaches into clinical practice and their role in informing treatment decisions is discussed. Key Messages: These new therapies require the accurate monitoring of disease progression, which along with diagnosis and prognosis, relies on the effective use of renal imaging techniques. There is growing support for the use of total kidney volume as a measure of cyst burden and as a prognostic predictor of renal function in ADPKD, showing promise as a marker of disease progression. © 2018 S. Karger AG, Basel. Copyright: All rights reserved. |
| تدمد: | 0250-8095 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::ee8eb36fcd8418084053f6aa394486a1Test https://www.scopus.com/inward/record.uri?eid=2-s2.0-85051747544&doi=10.1159/000491022&partnerID=40&md5=1b54955aa03d5e72f72f69c9330c90f9Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.RECOLECTA.....ee8eb36fcd8418084053f6aa394486a1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 02508095 |
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