دورية أكاديمية
An Estimation of Five-decade Long Monkeypox Case Fatality Rate: Systematic Review and Meta-analysis
| العنوان: | An Estimation of Five-decade Long Monkeypox Case Fatality Rate: Systematic Review and Meta-analysis |
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| المؤلفون: | Md. Aminul Islam, Tanvir Ahammed, Syed Toukir Ahmed Noor, Mohammad Nayeem Hasan, M. Nazmul Hoque, Ananda Tiwari, Harapan Harapan, Kuldeep Dhama, Tofazzal Islam, Prosun Bhattacharya |
| المصدر: | Journal of Pure and Applied Microbiology, Vol 16, Iss suppl 1, Pp 3036-3047 (2022) |
| بيانات النشر: | Journal of Pure and Applied Microbiology, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Microbiology |
| مصطلحات موضوعية: | monkeypox disease (mpxd), monkeypox virus (mpxv), zoonotic disease, case fatality rate (cfr), systematic review, meta-analysis, Microbiology, QR1-502 |
| الوصف: | On July 23, 2022 the World Health Organization (WHO) has announced the Monkeypox disease (MPXD) as a worldwide public health issue. This study conducts a systematic review and meta-analysis to determine the overall case fatality rate (CFR) of MPXD worldwide during 1970–2022. The tenure-tracked MPXD outbreaks associated with CFR were calculated based on available published data from six different periods (i.e., 1970-79, 1980-89, 1990-99, 2000-09, 2010-19, and 2000-2022). A total of 229 peer-reviewed accessible articles were investigated, of which, 17 articles met the inclusion and exclusion criteria. Most of the studies on MPXD CFR were published in the Democratic Republic of the Congo (DRC) providing 47% of data for the current meta-analysis. The overall pooled CFR of MPXD was 4.14% (range: 0.62% – 9.51%) during 1970–2022. In this study, total of 379 death cases were found from published MPXV based research articles where the pooled estimate CFR was 1.87%. The pooled CFR was higher during the earlier outbreak of the MPXD such as 10.71% in 1970-1979. With the progress of time, the CFR from MPXD followed a decreasing trend and reached 5.38% in 1980-1999 and 4.45% in 2000-2022. Young male children aged< 10 years were found to experience the worst outcome with a CFR of >73.0%. This is the first meta-analysis using 52 years of data which indicates that the CFR of MPXV is decreasing from previous years. The findings of this meta-analysis might be paramount for the policymakers to tackle MPXD and minimize the overall CFR of MPXD through strategic actions. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0973-7510 2581-690X |
| العلاقة: | https://microbiologyjournal.org/an-estimation-of-five-decade-long-monkeypox-case-fatality-rate-systematic-review-and-meta-analysisTest/; https://doaj.org/toc/0973-7510Test; https://doaj.org/toc/2581-690XTest |
| DOI: | 10.22207/JPAM.16.SPL1.16 |
| الوصول الحر: | https://doaj.org/article/f74a6cf56bf74cfd95854389d4e8faf9Test |
| رقم الانضمام: | edsdoj.f74a6cf56bf74cfd95854389d4e8faf9 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 09737510 2581690X |
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| DOI: | 10.22207/JPAM.16.SPL1.16 |