Timing and mechanism of ischemic stroke due to extracranial blunt traumatic cerebrovascular injury
| العنوان: | Timing and mechanism of ischemic stroke due to extracranial blunt traumatic cerebrovascular injury |
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| المؤلفون: | Mark R. Harrigan, Limin Zhao, Tracy H. Taylor, Christoph J. Griessenauer, J. Brett Fleming, Luis P. Cava, Andrei V. Alexandrov, Boyd F. Richards, Kristian Barlinn, Joel K. Curé, Duraid Younan |
| المصدر: | Journal of Neurosurgery. 118:397-404 |
| بيانات النشر: | Journal of Neurosurgery Publishing Group (JNSPG), 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | medicine.medical_specialty, Aspirin, medicine.diagnostic_test, business.industry, Trauma center, Digital subtraction angiography, Blunt, Blunt trauma, Internal medicine, Angiography, medicine, Cardiology, cardiovascular diseases, Radiology, business, Prospective cohort study, Cerebral angiography, medicine.drug |
| الوصف: | Object Extracranial cerebrovascular injury is believed to be an important cause of neurological injury in patients who have suffered blunt trauma. The authors sought to determine the timing and mechanisms of ischemic stroke in patients who suffered traumatic cerebrovascular injury (TCVI). Methods This is a prospective study of all patients with TCVI who were admitted to a Level I trauma center during a 28-month period. All patients who suffered blunt trauma and had risk factors for TCVI underwent screening CT angiography (CTA) of the head and neck on admission. All patients with either an ischemic stroke or CTA suggesting TCVI underwent confirmatory digital subtraction angiography (DSA). Patients with DSA-confirmed TCVI were treated with 325 mg aspirin daily; all patients were observed during their hospitalization for the occurrence of new ischemic stroke. In addition, a subset of patients with TCVI underwent transcranial Doppler ultrasonography monitoring for microembolic signals. Results A total of 112 patients had CTA findings suggestive of TCVI; 68 cases were confirmed by DSA. Overall, 7 patients had an ischemic stroke in the territory of the affected artery prior to or during admission. Four of the patients had their event prior to diagnosis with CTA and 2 occurred prior to DSA. In 1 patient the ischemic stroke was found to be due to an extracranial atherosclerotic carotid plaque, and this patient was excluded from further analysis. All patients with ischemic stroke had brain CT findings consistent with an embolic mechanism. Two (8.7%) of 23 monitored patients with TCVI had microembolic signals on transcranial Doppler ultrasonography. Conclusions Most ischemic strokes due to TCVI are embolic in nature and occur prior to screening CTA and initiation of treatment with aspirin. |
| تدمد: | 1933-0693 0022-3085 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::faa7c7a7ced52474155471666e55631fTest https://doi.org/10.3171/2012.11.jns121038Test |
| رقم الانضمام: | edsair.doi...........faa7c7a7ced52474155471666e55631f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19330693 00223085 |
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