التفاصيل البيبلوغرافية
| العنوان: |
Association between the cumulative triglyceride-glucose index and the recurrence of atrial fibrillation after radiofrequency catheter ablation. |
| المؤلفون: |
Qing YAN, Jia-Qi LIANG, Yi-De YUAN, Yuan LI, Jia-Li FAN, Wen-Huan WU, Pan XU, Jia-Hong XUE |
| المصدر: |
Journal of Geriatric Cardiology; Feb2024, Vol. 21 Issue 2, p200-210, 11p |
| مصطلحات موضوعية: |
BLOOD sugar analysis, ATRIAL fibrillation risk factors, RISK assessment, RECEIVER operating characteristic curves, BODY mass index, RESEARCH funding, RETROSPECTIVE studies, DESCRIPTIVE statistics, MANN Whitney U Test, MULTIVARIATE analysis, LACTATE dehydrogenase, LONGITUDINAL method, KAPLAN-Meier estimator, CREATINE kinase, ONE-way analysis of variance, STATISTICS, ATRIAL fibrillation, TRIGLYCERIDES, DISEASE relapse, CATHETER ablation, CONFIDENCE intervals, DATA analysis software, POSTOPERATIVE period, PROPORTIONAL hazards models, MYOCARDIAL depressants, DISEASE risk factors |
| مصطلحات جغرافية: |
CHINA |
| مستخلص: |
BACKGROUND Triglyceride-glucose (TyG) index values are a new surrogate marker for insulin resistance. This study aimed to explore the relationship between cumulative TyG index values and atrial fibrillation (AF) recurrence after radiofrequency catheter ablation (RFCA). METHODS A total of 576 patients with AF who underwent RFCA at the Second Affiliated Hospital of Xi'an Jiaotong University were included in this study. The participants were grouped based on cumulative TyG index values tertiles within 3 months after ablation. Cox regression and restricted cubic spline analyses were used to determine the relationship between cumulative TyG index values and AF recurrence. The predictive value of all risk factors was assessed by receiver operating curve analysis. RESULTS There were 375 patients completed the study (age: 63.23 ± 10.73 years, 64.27% male). The risk of AF recurrence increased with increasing cumulative TyG index values tertiles. After adjusting for potential confounders, patients in the medium cumulative TyG index group [hazard ratio (HR) = 4.949, 95% CI: 1.778-13.778, P = 0.002] and the high cumulative TyG index group (HR = 8.716, 95% CI: 3.371-22.536, P < 0.001) had a higher risk of AF recurrence than those in the low cumulative TyG index group. The restricted cubic spline regression model also showed an increased risk of AF recurrence with increasing cumulative TyG index values. When considering cumulative TyG index values, left atrial diameter, and lactate dehydrogenase levels as a comprehensive factor, the model could effectively predict AF recurrence after RFCA [area under the curve (AUC) = 0.847, 95% CI: 0.797-0.897, P < 0.001]. CONCLUSIONS Cumulative TyG index values were a risk factor for AF recurrence after RFCA. Monitoring longitudinal TyG index values may assist with optimized for risk stratification and outcome prediction for AF recurrence. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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