التفاصيل البيبلوغرافية
| العنوان: |
Renal Denervation for the Treatment of Hypertension: Making a New Start, Getting It Right |
| المؤلفون: |
Martin B. Leon, Michael A. Weber, Ajay Kirtane, David E. Kandzari, Raymond R. Townsend, Laura Mauri |
| المصدر: |
J Clin Hypertens (Greenwich) |
| بيانات النشر: |
John Wiley and Sons Inc., 2015. |
| سنة النشر: |
2015 |
| مصطلحات موضوعية: |
medicine.medical_specialty, Future studies, Renin secretion, Endocrinology, Diabetes and Metabolism, Central nervous system, Kidney, Internal medicine, Internal Medicine, medicine, Humans, In patient, Treatment Failure, Sympathectomy, Randomized Controlled Trials as Topic, Denervation, business.industry, Editorials, Clinical trial, medicine.anatomical_structure, Hypertension, Cardiology, Catheter Ablation, Cardiology and Cardiovascular Medicine, business, Sodium retention |
| الوصف: |
The renal nerves contribute to hypertension through effects in the kidney that enhance sodium retention and renin secretion, and by effects in the central nervous system that increase systemic sympathetic activity. Therefore, targeting the renal nerves provides a logical basis for treating hypertension. Several trials of renal denervation––achieved by applying radiofrequency energy through catheters placed in the renal arteries–– have been completed. Clinical results have been inconsistent, however, partly because of factors related to the ablation technique and partly because these studies have been performed in patients with the inadequately defined clinical condition of “treatment-resistant hypertension.” This statement now explains our conclusion that future studies of renal denervation should be guided by the established randomized, controlled clinical trial designs used for studying antihypertensive drugs and other treatments for hypertension. © 2015 Wiley Periodicals, Inc. |
| اللغة: |
English |
| الوصول الحر: |
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441ce9537fd40a1e7b073eeb05a0187bTest
https://europepmc.org/articles/PMC8032088Test/ |
| حقوق: |
OPEN |
| رقم الانضمام: |
edsair.doi.dedup.....441ce9537fd40a1e7b073eeb05a0187b |
| قاعدة البيانات: |
OpenAIRE |
