Stiff-Man Syndrome Associated with Antecedent Myasthenia Gravis and Organ-Specific Autoimmunopathy
| العنوان: | Stiff-Man Syndrome Associated with Antecedent Myasthenia Gravis and Organ-Specific Autoimmunopathy |
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| المؤلفون: | Yoshiteru Takiguchi, Yoshiyuki Yamaguchi, Akira Sato, Yoshihiro Takemura, Mamoru Narimatsu, Yoshimasa Aso, Toshihiko Inukai |
| المصدر: | Internal Medicine. 36:308-311 |
| بيانات النشر: | Japanese Society of Internal Medicine, 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | Adult, musculoskeletal diseases, Pathology, medicine.medical_specialty, animal structures, Antecedent (logic), Glutamate decarboxylase, Stiff-Person Syndrome, Thyroiditis, Autoimmune Diseases, Cerebrospinal fluid, Immunopathology, Diabetes mellitus, Myasthenia Gravis, Internal Medicine, medicine, Humans, Autoimmune disease, business.industry, Thyroiditis, Autoimmune, General Medicine, equipment and supplies, medicine.disease, Myasthenia gravis, Diabetes Mellitus, Type 1, Immunology, Female, business |
| الوصف: | We describe a case of stiff-man syndrome accompanied by diabetes mellitus, Hashimoto's thyroiditis and the antecedent myasthenia gravis. The diagnosis of stiff-man syndrome was made based on not only clinical findings and the characteristic electromyographic pattern but also the presence of antibodies to glutamic acid decarboxylase in the serum and cerebrospinal fluid. Stiff-man syndrome is known to be associated with organ-specific autoimmunopathy including insulin-dependent diabetes mellitus. The present case is the first one that stiff-man syndrome was preceded by myasthenia gravis of organ-specific autoimmunopathy. Stiff-man syndrome in the present case probably represents the one of fully expressed manifestations from the broad spectrum of organ-specific autoimmunopathy caused by the loss of self-tolerance. |
| تدمد: | 1349-7235 0918-2918 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d440be2951f5ce65e89fc66c681b797Test https://doi.org/10.2169/internalmedicine.36.308Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8d440be2951f5ce65e89fc66c681b797 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13497235 09182918 |
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