Acquired Coagulation Factor V Inhibitor That Was Successfully Treated with Oral Corticosteroid Therapy
| العنوان: | Acquired Coagulation Factor V Inhibitor That Was Successfully Treated with Oral Corticosteroid Therapy |
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| المؤلفون: | Hiromichi Bamba, Minami Nakagawa, Masaki Iwasa, Kousuke Hiroe, Katsuyuki Kito, Rie Osaki, Akira Andoh, Masahiro Kawahara, Kazuki Kakuda, Osamu Inatomi, Yoshihiro Yokota, Shigeki Sakai |
| المصدر: | Internal Medicine. 60:2663-2666 |
| بيانات النشر: | Japanese Society of Internal Medicine, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, pancreatic cancer, Factor V inhibitor, Oral prednisolone, Gastroenterology, corticosteroids, Adrenal Cortex Hormones, Pancreatic cancer, Internal medicine, Internal Medicine, medicine, Humans, Blood Coagulation, factor V inhibitor, Aged, Blood Coagulation Factor Inhibitors, biology, business.industry, Factor V, General Medicine, Coagulation factor V, medicine.disease, Coagulation, Corticosteroid therapy, biology.protein, Female, Blood Coagulation Tests, Antibody, Coagulation factor V inhibitor, business |
| الوصف: | Acquired coagulation factor V (FV) inhibitors are rare disorders in which antibodies against FV develop under various conditions. We herein report the case of a 71-year-old woman with FV inhibitor during radiochemotherapy for pancreatic cancer. Multiple purpuras suddenly appeared on her bilateral upper limbs with prolonged coagulation data (APTT 97.3 seconds). The FV activity was less than 3% and the FV inhibitor was positive (1.7 B.U./mL). Oral prednisolone induced a rapid normalization of the coagulation data and FV activity and a rapid disappearance of FV inhibitor within 7 days. Early diagnosis and treatment may therefore be important in cases of FV inhibitor. |
| تدمد: | 1349-7235 0918-2918 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d0c32a4b1d148e103410a4c30390c3Test https://doi.org/10.2169/internalmedicine.7453-21Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....07d0c32a4b1d148e103410a4c30390c3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13497235 09182918 |
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