دورية أكاديمية
Prodromal Alzheimer's Disease Presenting as Cerebral Amyloid Angiopathy-Related Inflammation with Spontaneous Amyloid-Related Imaging Abnormalities and High Cerebrospinal Fluid Anti-Aβ Autoantibodies
| العنوان: | Prodromal Alzheimer's Disease Presenting as Cerebral Amyloid Angiopathy-Related Inflammation with Spontaneous Amyloid-Related Imaging Abnormalities and High Cerebrospinal Fluid Anti-Aβ Autoantibodies |
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| المؤلفون: | PIAZZA, FABRIZIO, Boncoraglio, G, Savoiardo, M, Farina, L, DI FRANCESCO, JACOPO COSIMO, Prioni, S, Tagliavini, F, Parati, E, Giaccone, G. |
| المساهمون: | Piazza, F, Boncoraglio, G, Savoiardo, M, Farina, L, DI FRANCESCO, J, Prioni, S, Tagliavini, F, Parati, E, Giaccone, G |
| بيانات النشر: | IOS Press NL |
| سنة النشر: | 2015 |
| المجموعة: | Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive) |
| مصطلحات موضوعية: | Alzheimer's disease, amyloid-related imaging abnormalitie, anti-Aβ autoantibodie, cerebral amyloid angiopathy, cerebral amyloid angiopathy-related inflammation, subarachnoid hemorrhage, MED/46 - SCIENZE TECNICHE DI MEDICINA DI LABORATORIO |
| الوصف: | Cerebral amyloid angiopathy-related inflammation (CAA-ri), a rare form of vasculitis associated with amyloid-β (Aβ) deposition in vessel walls, has been proposed as a spontaneous human model of the amyloid-related imaging abnormalities (ARIA) occurring after anti-Aβ immunotherapy for the treatment of Alzheimer's disease (AD). We describe a case of a patient with biopsy-proven CAA-ri and prodromal AD, confirmed by means of neuropsychological examination after 20 months follow-up, presenting with ARIA and high levels of cerebrospinal fluid anti-Aβ autoantibodies. This case further supports the analogies between the inflammatory response driven by anti-Aβ immunotherapy and that spontaneously occurring in CAA-ri. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | STAMPA |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/25537009; info:eu-repo/semantics/altIdentifier/wos/WOS:000351583900004; volume:45; issue:2; firstpage:363; lastpage:367; numberofpages:5; journal:JOURNAL OF ALZHEIMER'S DISEASE; https://hdl.handle.net/10281/61983Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84925347817 |
| DOI: | 10.3233/JAD-142376 |
| الإتاحة: | https://doi.org/10.3233/JAD-142376Test https://hdl.handle.net/10281/61983Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.E33B649 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3233/JAD-142376 |
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