المؤلفون: Heikkinen, Sami, Huber, Nadine, Katisko, Kasper, Kokkola, Tarja, Hartikainen, Paivi, Kruger, Johanna, Leinonen, Ville, Korhonen, Ville E., Herukka, Sanna-Kaisa, Remes, Anne M., Borroni, Barbara, Alberici, Antonella, Libri, Ilenia, Solje, Eino, Haapasalo, Annakaisa

المساهمون: Department of Neurosciences, Faculty of Medicine, Clinicum

مصطلحات موضوعية: Biomarker, C9orf72, Grn, Mapt, Tdp-43, cathepsin S, Diagnostics, Frontotemporal dementia, Proteinopathy, Tau, 3112 Neurosciences

وصف الملف: application/pdf

العلاقة: Heikkinen , S , Huber , N , Katisko , K , Kokkola , T , Hartikainen , P , Kruger , J , Leinonen , V , Korhonen , V E , Herukka , S-K , Remes , A M , Borroni , B , Alberici , A , Libri , I , Solje , E & Haapasalo , A 2023 , ' Serum Cathepsin S Levels Do Not Show Alterations in Different Clinical, Neuropathological, or Genetic Subtypes of Frontotemporal Dementia Patients nor in Comparison to Healthy Control Individuals ' , Journal of Alzheimer's Disease , vol. 93 , no. 2 , pp. 395-401 . https://doi.org/10.3233/JAD-221060Test; e49253ab-c09f-4fc6-b09e-d2df0016ab48; http://hdl.handle.net/10138/571125Test; 000989648900001

الإتاحة: http://hdl.handle.net/10138/571125Test

المؤلفون: Heikkinen, Sami, Huber, Nadine, Katisko, Kasper, Kokkola, Tarja, Hartikainen, Päivi, Krüger, Johanna, Leinonen, Ville, Korhonen, Ville E, Herukka, Sanna-Kaisa, Remes, Anne M, Borroni, Barbara, Alberici, Antonella, Libri, Ilenia, Solje, Eino, Haapasalo, Annakaisa

المساهمون: Kliininen lääketiede, A.I. Virtanen -instituutti

مصطلحات موضوعية: biomarker, cathepsin S, C9orf72, diagnostics, frontotemporal dementia, GRN, MAPT, proteinopathy, tau, TDP-43

وصف الملف: 395-401

العلاقة: Journal of Alzheimer's disease; https://doi.org/10.3233/JAD-221060Test; 93; https://erepo.uef.fi/handle/123456789/30066Test

الإتاحة: https://doi.org/10.3233/JAD-221060Test
https://erepo.uef.fi/handle/123456789/30066Test

المؤلفون: Hannonen, Sanna, Andberg, Sami, Kärkkäinen, Virve, Rusanen, Minna, Lehtola, Juha-Matti, Saari, Toni, Korhonen, Ville, Hokkanen, Laura, Hallikainen, Merja, Hänninen, Tuomo, Leinonen, Ville, Kaarniranta, Kai, Bednarik, Roman, Koivisto, Anne M.

المساهمون: Department of Psychology and Logopedics, University of Helsinki, Department of Neurosciences, HUS Neurocenter, Neurologian yksikkö, Geriatrian yksikkö

مصطلحات موضوعية: Alzheimer's disease, biomarker, CERAD, eye tracking, King-Devick, mild cognitive impairment, saccadic eye movements, CERAD NEUROPSYCHOLOGICAL BATTERY, KING-DEVICK TEST, ASSOCIATION WORKGROUPS, DIAGNOSTIC GUIDELINES, NATIONAL INSTITUTE, RECOMMENDATIONS, DEMENTIA, ALLELE, 3112 Neurosciences, 3124 Neurology and psychiatry, 515 Psychology, Neuropsychology

وصف الملف: application/pdf

العلاقة: We are deeply grateful to all of the study participants. We also thank BEGAD research project study nurses Ulla Vanhanen, Kati Monttinen, and Kristiina Holopainen for recruiting the study participants. We thank biostatistician Tuomas Selander for help with the statistical analysis. This work was supported by Juho and Lempi Pitkanen Foundation.; Hannonen , S , Andberg , S , Kärkkäinen , V , Rusanen , M , Lehtola , J-M , Saari , T , Korhonen , V , Hokkanen , L , Hallikainen , M , Hänninen , T , Leinonen , V , Kaarniranta , K , Bednarik , R & Koivisto , A M 2022 , ' Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer's Disease ' , Journal of Alzheimer's Disease , vol. 88 , no. 2 , pp. 609-618 . https://doi.org/10.3233/JAD-215551Test; ORCID: /0000-0001-8342-9248/work/117173311; cf23b6b3-9995-43a9-a640-5ab028bd110c; http://hdl.handle.net/10138/346799Test; 000828034300020

الإتاحة: http://hdl.handle.net/10138/346799Test

المؤلفون: Lukkarinen, Heikki, Tesseur, Ina, Pemberton, Darrel, Van der Ark, Peter, Timmers, Maarten, Slemmon, Randy, Janssens, Luc, Streffer, Johannes, Van Nueten, Luc, Bottelbergs, Astrid, Rauramaa, Tuomas, Koivisto, Anne M., Herukka, Sanna-Kaisa, Korhonen, Ville E., Junkkari, Antti, Hiltunen, Mikko, Engelborghs, Sebastiaan, Blennow, Kaj, Zetterberg, Henrik, Kolb, Hartmuth C., Leinonen, Ville

المساهمون: Department of Neurosciences, University of Helsinki, Geriatrian yksikkö, Helsinki University Hospital Area

مصطلحات موضوعية: A beta(42), biomarkers, idiopathic normal pressure hydrocephalus, neurofilament light, neurogranin, P-tau, T-tau, CORTICAL BRAIN BIOPSY, ALZHEIMERS-DISEASE, CSF BIOMARKERS, PROTEIN NEUROGRANIN, PHOSPHORYLATED TAU, SYNAPTIC PROTEIN, AMYLOID-BETA, DIAGNOSIS, INCREASE, Neurosciences, Neurology and psychiatry

وصف الملف: application/pdf

العلاقة: We would like to acknowledge Marita Parviainen, RN, for assistance and cognitive testing. The study was funded by Janssen R-D, a division of Janssen Pharmaceutica NV, Kuopio University Hospital VTR (#5252614) fund and Sigrid Juselius Foundation. HZ is a Wallenberg Scholar supported by grants from the Swedish Research Council (#2018-02532), the European Research Council (#681712), Swedish State Support for Clinical Research (#ALFGBG-720931), the Alzheimer Drug Discovery Foundation (ADDF), USA (#201809-2016862), and the UK Dementia Research Institute at UCL. KB is supported by the Swedish Research Council (#2017-00915), the Alz-heimer Drug Discovery Foundation (ADDF), USA (#RDAPB-201809-2016615), the Swedish Alzhei-mer Foundation (#AF-742881), Hj?rnfonden, Sweden (#FO2017-0243), the Swedish state under the agreement between the Swedish government and the County Councils, the ALF-agreement (#ALFGBG-715986), and European Union Joint Program for Neurodegenerative Disorders (JPND2019-466-236). We would like to acknowledge Marita Parviainen, RN, for assistance and cognitive testing. The study was funded by Janssen R&D, a division of Janssen Pharmaceutica NV, Kuopio University Hospital VTR (#5252614) fund and Sigrid Juselius Foundation. HZ is a Wallenberg Scholar supported by grants from the Swedish Research Council (#2018-02532), the European Research Council (#681712), Swedish State Support for Clinical Research (#ALFGBG-720931), the Alzheimer Drug Discovery Foundation (ADDF), USA (#201809-2016862), and the UK Dementia Research Institute at UCL. KB is supported by the Swedish Research Council (#2017-00915), the Alzheimer Drug Discovery Foundation (ADDF), USA (#RDAPB-201809-2016615), the Swedish Alzheimer Foundation (#AF-742881), Hjärnfonden, Sweden (#FO2017-0243), the Swedish state under the agreement between the Swedish government and the County Councils, the ALF-agreement (#ALFGBG-715986), and European Union Joint Program for Neurodegenerative Disorders (JPND2019-466-236).; Lukkarinen , H , Tesseur , I , Pemberton , D , Van der Ark , P , Timmers , M , Slemmon , R , Janssens , L , Streffer , J , Van Nueten , L , Bottelbergs , A , Rauramaa , T , Koivisto , A M , Herukka , S-K , Korhonen , V E , Junkkari , A , Hiltunen , M , Engelborghs , S , Blennow , K , Zetterberg , H , Kolb , H C & Leinonen , V 2021 , ' Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus ' , Journal of Alzheimer's Disease , vol. 80 , no. 4 , pp. 1629-1642 . https://doi.org/10.3233/JAD-201361Test; http://hdl.handle.net/10138/331743Test; b44c09e8-f378-4b9d-b8d0-f55a3cdd882b; 000642444400027

الإتاحة: http://hdl.handle.net/10138/331743Test

المؤلفون: Katisko, Kasper, Kokkonen, Nina, Krüger, Johanna, Hartikainen, Päivi, Koivisto, Anne, Helisalmi, Seppo, Korhonen, Ville, Kokki, Merja, Tuusa, Jussi, Herukka, Sanna-Kaisa, Solje, Eino, Haapasalo, Annakaisa, Tasanen, Kaisa, Remes, Anne

المساهمون: School of Medicine / Clinical Medicine, A.I. Virtanen -instituutti

مصطلحات موضوعية: autoantibody, bullous pemphigoid, C9orf72, comorbidity, dementia, frontotemporal dementia, immunology

وصف الملف: 743-750

العلاقة: Journal of Alzheimer's Disease; http://dx.doi.org/10.3233/JAD-180624Test; 66; https://erepo.uef.fi/handle/123456789/7917Test

الإتاحة: https://doi.org/10.3233/JAD-180624Test
https://erepo.uef.fi/handle/123456789/7917Test

المؤلفون: Rostalski, Hannah, Korhonen, Ville, Kuulasmaa, Teemu, Solje, Eino, Krüger, Johanna, Gen, Finn, Kaivola, Karri, Eide, Per Kristian, Lambert, Jean-Charles, Julkunen, Valtteri, Tienari, Pentti, Remes, Anne, Leinonen, Ville, Hiltunen, Mikko, Haapasalo, Annakaisa

المساهمون: Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 (RID-AGE), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille)

المصدر: ISSN: 1387-2877 ; Journal of Alzheimer's Disease ; https://hal.science/hal-04277993Test ; Journal of Alzheimer's Disease, 2021, 83 (3), pp.1325-1332. ⟨10.3233/JAD-210599⟩.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

العلاقة: hal-04277993; https://hal.science/hal-04277993Test

الإتاحة: https://doi.org/10.3233/JAD-210599Test
https://hal.science/hal-04277993Test

المؤلفون: Ylä-Herttuala, Salla, Hakulinen, Mikko, Poutiainen, Pekka, Laitinen, Tiina M., Koivisto, Anne M., Remes, Anne M., Hallikainen, Merja, Lehtola, Juha-Matti, Saari, Toni, Korhonen, Ville, Könönen, Mervi, Vanninen, Ritva, Mussalo, Hanna, Laitinen, Tomi, Mervaala, Esa, Castelo-Branco, Miguel

المصدر: Journal of Alzheimer's Disease; 2020, Vol. 79 Issue 1, p153-161, 9p

مصطلحات موضوعية: SLEEP apnea syndromes, CEREBRAL amyloid angiopathy, OLDER patients, ALZHEIMER'S disease, GLUCOSE metabolism, MAGNETIC resonance imaging, SEVERITY of illness index, AMINES, RADIOPHARMACEUTICALS, DEOXY sugars, CEREBRAL cortex, PEPTIDES, THIAZOLES

المؤلفون: Jääskeläinen, Olli, Solje, Eino, Hall, Anette, Katisko, Kasper, Korhonen, Ville, Tiainen, Mika, Kangas, Antti J., Helisalmi, Seppo, Pikkarainen, Maria, Koivisto, Anne, Hartikainen, Päivi, Hiltunen, Mikko, Ala-Korpela, Mika, Soininen, Hilkka, Soininen, Pasi, Haapasalo, Annakaisa, Remes, Anne M., Herukka, Sanna-Kaisa

المصدر: Journal of Alzheimer's Disease; 2019, Vol. 72 Issue 1, p127-137, 11p

مصطلحات موضوعية: FRONTOTEMPORAL lobar degeneration, HIGH density lipoproteins, NUCLEAR magnetic resonance spectroscopy, CHOLESTEROL, ALZHEIMER'S disease, LIPOPROTEIN A, HDL cholesterol, RESEARCH, DNA, RESEARCH methodology, RETROSPECTIVE studies, EVALUATION research, MEDICAL cooperation, COMPARATIVE studies, RESEARCH funding, LONGITUDINAL method

المؤلفون: Luikku, Antti J., Hall, Anette, Nerg, Ossi, Koivisto, Anne M., Hiltunen, Mikko, Helisalmi, Seppo, Herukka, Sanna-Kaisa, Junkkari, Antti, Sutela, Anna, Kojoukhova, Maria, Korhonen, Ville, Mattila, Jussi, Lötjönen, Jyrki, Rummukainen, Jaana, Alafuzoff, Irina, Jääskeläinen, Juha E., Remes, Anne M., Solomon, Alina, Kivipelto, Miia, Soininen, Hilkka

المصدر: Journal of Alzheimer's Disease; 2019, Vol. 71 Issue 4, p1233-1243, 11p

مصطلحات موضوعية: ALZHEIMER'S patients, HYDROCEPHALUS, RECEIVER operating characteristic curves, ALZHEIMER'S disease, BRAIN diseases

المؤلفون: Benussi, Luisa, Katisko, Kasper, Helisalmi, Seppo, Remes, Anne M., Hartikainen, Päivi, Koivisto, Anne M., Herukka, Sanna-Kaisa, Solje, Eino, Kokkonen, Nina, Tuusa, Jussi, Tasanen, Kaisa, Krüger, Johanna, Korhonen, Ville E., Kokki, Merja, Haapasalo, Annakaisa

المصدر: Journal of Alzheimer's Disease; 2018, Vol. 66 Issue 2, p743-750, 8p

مصطلحات موضوعية: FRONTOTEMPORAL lobar degeneration, BULLOUS pemphigoid, IMMUNOLOGY, EPIDEMIOLOGY, AUTOANTIBODIES, ANTIGENS, COLLAGEN, COMPARATIVE studies, DNA, RESEARCH methodology, MEDICAL cooperation, RESEARCH, EVALUATION research

مصطلحات جغرافية: FINLAND