دورية أكاديمية

Magnetically-refreshable receptor platform structures for reusable nano-biosensor chips.

التفاصيل البيبلوغرافية
العنوان: Magnetically-refreshable receptor platform structures for reusable nano-biosensor chips.
المؤلفون: Haneul Yoo, Dong Jun Lee, Dong-guk Cho, Juhun Park, Ki Wan Nam, Young Tak Cho, Jae Yeol Park, Xing Chen, Seunghun Hong
المصدر: Nanotechnology; 1/29/2016, Vol. 27 Issue 4, p1-1, 1p
مصطلحات موضوعية: BIOSENSORS, CHEMICAL reactions, MOLECULAR physics, DEBYE length, ELECTROCHEMISTRY
مستخلص: We developed a magnetically-refreshable receptor platform structure which can be integrated with quite versatile nano-biosensor structures to build reusable nano-biosensor chips. This structure allows one to easily remove used receptor molecules from a biosensor surface and reuse the biosensor for repeated sensing operations. Using this structure, we demonstrated reusable immunofluorescence biosensors. Significantly, since our method allows one to place receptor molecules very close to a nano-biosensor surface, it can be utilized to build reusable carbon nanotube transistor-based biosensors which require receptor molecules within a Debye length from the sensor surface. Furthermore, we also show that a single sensor chip can be utilized to detect two different target molecules simply by replacing receptor molecules using our method. Since this method does not rely on any chemical reaction to refresh sensor chips, it can be utilized for versatile biosensor structures and virtually-general receptor molecular species. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:09574484
DOI:10.1088/0957-4484/27/4/045502