Electrophysiological Insights into Three Modalities of Left Bundle Branch Area Pacing in Patients Indicated for Pacing Therapy
| العنوان: | Electrophysiological Insights into Three Modalities of Left Bundle Branch Area Pacing in Patients Indicated for Pacing Therapy |
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| المؤلفون: | Xia Sheng, Min Wang, Yiwen Pan, Jiefang Zhang, Guosheng Fu |
| المصدر: | International Heart Journal. 62:78-86 |
| بيانات النشر: | International Heart Journal (Japanese Heart Journal), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Heart Ventricles, Bundle-Branch Block, Ventricular Septum, 030204 cardiovascular system & hematology, Electrocardiography, 03 medical and health sciences, QRS complex, 0302 clinical medicine, Heart Conduction System, Internal medicine, Outcome Assessment, Health Care, Left bundle branch, Humans, Medicine, In patient, Prospective Studies, 030212 general & internal medicine, Aged, Procedure time, Aged, 80 and over, Heart Failure, Modalities, business.industry, Cardiac Pacing, Artificial, General Medicine, Middle Aged, medicine.disease, Electrophysiological Phenomena, Electrophysiology, Ventricular activation, Echocardiography, Heart failure, Cardiology, Female, Cardiac Electrophysiology, Cardiology and Cardiovascular Medicine, business, Follow-Up Studies |
| الوصف: | Left bundle branch pacing (LBBP) has been adopted as a new pacing therapy whether in routine pacing or patients with heart failure, but the criteria for a completely captured LBBP are too complicated and have a low success rate in routine clinical practice.Consecutive patients with pacing therapy indications were enrolled. Left bundle branch area pacing (LBBAP) was conducted, and the presence of LBB potential, paced QRS duration, stimulus to left ventricular activation time (Stim-LVAT), and LBB potential to left ventricular activation time (LBB po-LVAT) were determined and utilized to characterize LBBAP modalities. Pacing parameters and safety were assessed at 6-month follow-up. LBBAP succeeded in 95.6% of patients (103/106) who completed the 6-month follow-up. Complete LBBP was achieved in 21 (20%) patients, characterized with a short Stim-LVAT equal to LBB po-LVAT. Incomplete LBBP was achieved in 58 (56%) patients with a short Stim-LVAT equal to LBB po-LVAT at a high pacing output and a relatively longer Stim-LVAT at a low pacing output. Deep septal pacing (DSP) characterized with no LBB potential and a longer Stim-LVAT (83.3 ± 7.7 ms) than that in LBBP (71.37 ± 7.1 ms, P < 0.01 versus DSP) was observed in 24 (23%) patients. Complete LBBP had a longer total procedure time and longer fluoroscopic time than the other two groups.This study describes the similarities and differences in electrophysiological characteristics and the possible mechanisms of the different types of LBBAP, classified into 3 modalities in routine clinical practice, each with narrow paced QRS duration and stable parameters, indicating LBBAP can be a near-physiological pacing modality. |
| تدمد: | 1349-3299 1349-2365 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36cc97638c226335b53bb409b2f94c7Test https://doi.org/10.1536/ihj.20-490Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....f36cc97638c226335b53bb409b2f94c7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13493299 13492365 |
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