كتاب
Synthesis of Low Abundant Vitamin D Metabolites and Assaying Their Distribution in Human Serum by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) as a New Tool for Diagnosis and Risk Prediction of Vitamin DRelated Diseases
| العنوان: | Synthesis of Low Abundant Vitamin D Metabolites and Assaying Their Distribution in Human Serum by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) as a New Tool for Diagnosis and Risk Prediction of Vitamin DRelated Diseases |
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| المؤلفون: | Kattner, Lars, Volmer, Dietrich A. |
| المصدر: | https://www.intechopen.com/books/5269Test. |
| بيانات النشر: | IntechOpen |
| سنة النشر: | 2017 |
| المجموعة: | IntechOpen (E-Books) |
| مصطلحات موضوعية: | A Critical Evaluation of Vitamin D - Basic Overview |
| الوصف: | This chapter provides an overview of versatile and efficient chemical syntheses of vitamin D derivatives by application of either linear or convergent synthesis approaches. Synthesis of the most relevant naturally occurring vitamin D metabolites and their deuterated counterparts to use as calibration and reference standards in LC-MS/MS assays is also shown. The chapter then summarizes the most important mass spectrometric approaches to quantify important vitamin D metabolites in human biofluids. In addition, new developments are described that are aimed at the pathobiological interpretation of the measured vitamin D metabolite distributions in various human diseases. |
| نوع الوثيقة: | book part |
| اللغة: | English |
| ردمك: | 978-953-51-3083-3 953-51-3083-8 |
| العلاقة: | https://mts.intechopen.com/articles/show/title/synthesis-of-low-abundant-vitamin-d-metabolites-and-assaying-their-distribution-in-human-serum-by-liTest |
| DOI: | 10.5772/64518 |
| الإتاحة: | https://doi.org/10.5772/64518Test https://mts.intechopen.com/articles/show/title/synthesis-of-low-abundant-vitamin-d-metabolites-and-assaying-their-distribution-in-human-serum-by-liTest |
| حقوق: | https://creativecommons.org/licenses/by/3.0Test/ |
| رقم الانضمام: | edsbas.46E7D89B |
| قاعدة البيانات: | BASE |
| ردمك: | 9789535130833 9535130838 |
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| DOI: | 10.5772/64518 |