كتاب
Mass Spectrometry for Cancer Biomarkers
| العنوان: | Mass Spectrometry for Cancer Biomarkers |
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| المؤلفون: | Albulescu, Radu, Petrescu, Andrei Jose, Sarbu, Mirela, Grigore, Alice, Ica, Raluca, Munteanu, Cristian V. A., Albulescu, Adrian, Militaru, Ioana V., Zamfir, Alina-Diana, Petrescu, Stefana, Tanase, Cristiana |
| المصدر: | https://www.intechopen.com/books/6914Test. |
| بيانات النشر: | IntechOpen |
| سنة النشر: | 2019 |
| المجموعة: | IntechOpen (E-Books) |
| مصطلحات موضوعية: | Proteomics Technologies and Applications |
| الوصف: | Cancer is considered as the second cause of morbidity and also mortality, after cardiovascular diseases. Despite the immense progress in efficacious biomarkers made in the present time, there are very few of them that can timely detect cancers or that can predict treatment outcomes or stratify patients according to their response to the treatment. Among other modern instruments involved in the research of this disease, proteomics emerged strongly, since it analyzes the “molecular effectors.” Although it has some setbacks (like the lack of amplification of the signal), it is however one of the best means of investigating the presence and causes and predicting the evolution patterns of the disease. This chapter describes briefly pre-analytical (pre-MS steps), the main concepts, and the MS equipment used for such applications, followed by the presentation of several proteomic applications in melanoma, glioblastoma, pancreatic cancer, and colon cancer. |
| نوع الوثيقة: | book part |
| اللغة: | English |
| ردمك: | 978-1-78984-610-2 1-78984-610-2 |
| العلاقة: | https://mts.intechopen.com/articles/show/title/mass-spectrometry-for-cancer-biomarkersTest |
| DOI: | 10.5772/intechopen.85609 |
| الإتاحة: | https://doi.org/10.5772/intechopen.85609Test https://mts.intechopen.com/articles/show/title/mass-spectrometry-for-cancer-biomarkersTest |
| حقوق: | https://creativecommons.org/licenses/by/3.0Test/ |
| رقم الانضمام: | edsbas.D2E8EE64 |
| قاعدة البيانات: | BASE |
| ردمك: | 9781789846102 1789846102 |
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| DOI: | 10.5772/intechopen.85609 |