The functional neuroanatomy of verbal memory in Alzheimer’s disease: [18F]-Fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) correlates of recency and recognition memory
| العنوان: | The functional neuroanatomy of verbal memory in Alzheimer’s disease: [18F]-Fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) correlates of recency and recognition memory |
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| المؤلفون: | Adam M. Staffaroni, M. Mandelkern, Rebecca J. Melrose, David L. Sultzer, Dylan G. Harwood, Hannah Riskin-Jones, Lorraine P. Leskin |
| المصدر: | Journal of Clinical and Experimental Neuropsychology. 39:682-693 |
| بيانات النشر: | Informa UK Limited, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.diagnostic_test, Recall, 05 social sciences, medicine.disease, Verbal learning, behavioral disciplines and activities, 050105 experimental psychology, Serial position effect, 03 medical and health sciences, Clinical Psychology, 0302 clinical medicine, Neurology, Positron emission tomography, medicine, Dementia, 0501 psychology and cognitive sciences, Orbitofrontal cortex, Neurology (clinical), Verbal memory, Psychology, Neuroscience, 030217 neurology & neurosurgery, Recognition memory |
| الوصف: | Introduction: The objective of this study was to distinguish the functional neuroanatomy of verbal learning and recognition in Alzheimer’s disease (AD) using the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) Word Learning task. Method: In 81 Veterans diagnosed with dementia due to AD, we conducted a cluster-based correlation analysis to assess the relationships between recency and recognition memory scores from the CERAD Word Learning Task and cortical metabolic activity measured using [18F]-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET). Results: AD patients (Mini-Mental State Examination, MMSE mean = 20.2) performed significantly better on the recall of recency items during learning trials than of primacy and middle items. Recency memory was associated with cerebral metabolism in the left middle and inferior temporal gyri and left fusiform gyrus (p |
| تدمد: | 1744-411X 1380-3395 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::786f3f9a300d125291744cff26399476Test https://doi.org/10.1080/13803395.2016.1255312Test |
| رقم الانضمام: | edsair.doi...........786f3f9a300d125291744cff26399476 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1744411X 13803395 |
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