Localized intrahepatic IgG4-related sclerosing cholangitis (IgG4-SC) as an additional type of IgG4-SC: a systematic analysis of 12 cases
| العنوان: | Localized intrahepatic IgG4-related sclerosing cholangitis (IgG4-SC) as an additional type of IgG4-SC: a systematic analysis of 12 cases |
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| المؤلفون: | Xiangwu Zheng, Kuvaneshan Ramen, Xiao-ke Ji, Yunfeng Shan, Xiuling Wu, Qiqiang Zeng, Zhengping Yu, Zhichao Mo, Qiyu Zhang, Mengtao Zhou |
| المصدر: | Scandinavian Journal of Gastroenterology. 53:312-318 |
| بيانات النشر: | Informa UK Limited, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Abdominal pain, Cholangitis, Sclerosing, Gastroenterology, Cholangiocarcinoma, Diagnosis, Differential, 03 medical and health sciences, 0302 clinical medicine, Cholangiography, Internal medicine, parasitic diseases, medicine, Humans, Diagnostic Errors, Aged, Disease entity, medicine.diagnostic_test, business.industry, fungi, Middle Aged, Abdominal Pain, Jaundice, Obstructive, Bile Ducts, Intrahepatic, Bile Duct Neoplasms, Immunoglobulin G, 030220 oncology & carcinogenesis, Female, 030211 gastroenterology & hepatology, Obstructive jaundice, medicine.symptom, business |
| الوصف: | IgG4-related sclerosing cholangitis (IgG4-SC), a recently defined disease entity, has been classified into four types based on the stricture regions revealed by cholangiography. However, localized intrahepatic IgG4-SC is not included into the classification. This study aimed to analyze and characterize localized intrahepatic IgG4-SC and justify the inclusion of this type into the classification.PubMed and Embase were searched for studies published from March 2001 to June 2017 reporting localized intrahepatic IgG4-SC. Data were obtained and analyzed from the included articles.Twelve cases of localized intrahepatic IgG4-SC were included. All patients were adults with the median age of 73 years (range 46-78), and had a male preponderance (88.9%). The most common clinical presentation was obstructive jaundice (50%), abdominal pain (25%) and absence of symptoms (25%). On imaging and macroscopically, localized intrahepatic IgG4-SC presented with three subtypes, i.e., mass-forming (n = 6, 50%), stricture (n = 5, 41.7%) and periductal infiltrating (n = 1, 8.3%) subtypes. Among the eight cases with diagnoses reported, six patients were misdiagnosed as intrahepatic cholangiocarcinoma; one was diagnosed as hepatic mass and one as IgG4-SC before biopsy or operation. Information on treatment was available on 10 cases; eight underwent surgical resection, one received steroid treatment alone and one underwent endoscopic biliary drainage. No relapse was noted in patients with surgical resection during a period of followed up.The localized intrahepatic IgG4-SC presents with mass-forming, stricture and periductal infiltrating subtypes, and should be recognized as an additional type of IgG4-SC according to the cholangiographic classification or anatomic site. |
| تدمد: | 1502-7708 0036-5521 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6507d4513903c7ef5551a24ac02f194Test https://doi.org/10.1080/00365521.2018.1424233Test |
| رقم الانضمام: | edsair.doi.dedup.....b6507d4513903c7ef5551a24ac02f194 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15027708 00365521 |
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