Tirofiban combined with heparin’s effect and safety in the treatment of mild to moderate acute ischemic stroke
| العنوان: | Tirofiban combined with heparin’s effect and safety in the treatment of mild to moderate acute ischemic stroke |
|---|---|
| المؤلفون: | Qingping Gong, Shengqi Fu, Weili He, Tao Qiu, Ming Chen, Xiaoyan Dai, Linming Huang, Qin Luo, Mingjin Wang, Hua Xiao, Changqing Li, Xiaoyong Deng, Juan Wang |
| المصدر: | Neurological Research. 43:220-224 |
| بيانات النشر: | Informa UK Limited, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Adult, Male, 0301 basic medicine, medicine.medical_specialty, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Humans, Medicine, Acute ischemic stroke, Aged, Ischemic Stroke, Aspirin, Heparin, business.industry, fungi, food and beverages, General Medicine, Tirofiban, Middle Aged, Clopidogrel, Treatment Outcome, 030104 developmental biology, Neurology, Cardiology, Female, Neurology (clinical), business, Platelet Aggregation Inhibitors, 030217 neurology & neurosurgery, medicine.drug |
| الوصف: | Tirofiban can be used to treat patients with acute ischemic stroke (AIS), this study was to evaluate the efficacy and safety of tirofiban combined with heparin in the treatment of mild to moderate AIS. A total of 98 patients with mild to moderate AIS randomly were divided into 2 groups within 48 h: the treatment group treated with tirofiban and, and the control group treated with aspirin + clopidogrel. The treatment group was given the same scheme as the control group after the treatment of tirofiban combined with heparin for 48 h. It was found that, compared with the control group, a significant decreased National Institute of Health stroke scale (NIHSS) was found in 48 h and 14 d, especially to the Barthel index (BI) in the treatment group (P 0.05). Furthermore, Modified Rankin Scale (MRS, ≤2) in the treatment group was significantly upregulated in 90 d (P 0.05). However, there were no significant differences in the adverse drug reactions between the two groups. It was indicated that nerve function and long-term prognosis in patients undergoing heparin for mild to moderate AIS were obviously improved than the control group. |
| تدمد: | 1743-1328 0161-6412 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67493f192f44abe6789b9ded8217e8dTest https://doi.org/10.1080/01616412.2020.1839690Test |
| رقم الانضمام: | edsair.doi.dedup.....d67493f192f44abe6789b9ded8217e8d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 17431328 01616412 |
|---|