نتائج البحث

1

Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma

المؤلفون: Edmund Kwok-Kwan Tung, Yu-Man Tsui, Karen Man-Fong Sze, Terence Kin Wah Lee, Daniel W.H. Ho, Irene Oi-Lin Ng

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Male, sphere formation, Dishevelled Proteins, Gene Expression, Receptors, G-Protein-Coupled, Mice, 0302 clinical medicine, Protein Phosphatase 1, Tumor Cells, Cultured, Medicine, Phosphorylation, chemistry.chemical_classification, Gene knockdown, Wnt/β-catenin, biology, Protein Stability, Liver Neoplasms, Wnt signaling pathway, Middle Aged, Dishevelled, Ubiquitin ligase, Oncology, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Female, Signal transduction, Research Paper, Protein Binding, Signal Transduction, Adult, Carcinoma, Hepatocellular, Ubiquitin-Protein Ligases, Protein Serine-Threonine Kinases, Models, Biological, 03 medical and health sciences, Cell Line, Tumor, Animals, Humans, Aged, business.industry, Cancer, Protein phosphatase 1, medicine.disease, Repressor Proteins, Disease Models, Animal, 030104 developmental biology, chemistry, post-translational modification, Immunology, biology.protein, Cancer research, tumorigenicity, business, Carrier Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90204d510d6b56ec2bbe3a312bf1843bTest
http://europepmc.org/articles/PMC5503623Test

2

RORα and RORγ expression inversely correlates with human melanoma progression

المؤلفون: Anna A. Brożyna, Wojciech Jóźwicki, Cezary Skobowiat, Andrzej Slominski, Anton M. Jetten

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Oncology, Keratinocytes, Male, Pathology, Skin Neoplasms, vitamin D, Disease, 0302 clinical medicine, Medicine, Neoplasm Metastasis, RORα, RORγ, Skin, Aged, 80 and over, Melanoma, Nuclear Receptor Subfamily 1, Group F, Member 1, Middle Aged, Nuclear Receptor Subfamily 1, Group F, Member 3, Tumor Pathology, 3. Good health, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Disease Progression, Melanocytes, Female, Research Paper, Adult, medicine.medical_specialty, Tumor suppressor gene, 03 medical and health sciences, Young Adult, Internal medicine, Cell Line, Tumor, Vitamin D and neurology, melanoma, Humans, melanocytic nevi, neoplasms, Nevus, Aged, Cell Proliferation, Neoplasm Staging, Retrospective Studies, business.industry, Gene Expression Profiling, Cancer, medicine.disease, 030104 developmental biology, Human melanoma, business, Biomedical sciences, Follow-Up Studies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933ad3c78fc52973fd2c2caf813dd945Test
http://europepmc.org/articles/PMC5325362Test

3

Next-generation sequencing reveals somatic mutations that confer exceptional response to everolimus

المصدر: Oncotarget
ResearcherID

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Somatic cell, Tuberous Sclerosis Complex 1 Protein, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Class Ib Phosphatidylinositol 3-Kinase, Genetics, Aged, 80 and over, BAP1, Neurofibromin 1, TOR Serine-Threonine Kinases, Lacrimal Apparatus, High-Throughput Nucleotide Sequencing, Sarcoma, Middle Aged, Kidney Neoplasms, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, mTOR, Female, medicine.drug, Research Paper, Adult, medicine.medical_specialty, Class I Phosphatidylinositol 3-Kinases, Antineoplastic Agents, Adenocarcinoma, Polymorphism, Single Nucleotide, DNA sequencing, 03 medical and health sciences, Young Adult, Stomach Neoplasms, Internal medicine, Tuberous Sclerosis Complex 2 Protein, medicine, Humans, Everolimus, Thyroid Neoplasms, Carcinoma, Renal Cell, PI3K/AKT/mTOR pathway, Predictive biomarker, Aged, business.industry, Tumor Suppressor Proteins, Head and neck cancer, Cancer, medicine.disease, TSC1, 030104 developmental biology, NF1, Drug Resistance, Neoplasm, Mutation, next-generation sequencing, Tumor Suppressor Protein p53, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029b1d948f0ecf95f7548daf9ddc13d6Test
http://europepmc.org/articles/PMC4891139Test

4

TRIB1 promotes colorectal cancer cell migration and invasion through activation MMP-2 via FAK/Src and ERK pathways

المؤلفون: Xiangning Meng, Donglin Sun, Jing Bai, Feng Chen, Haiming Sun, Chunyu Zhang, Bo Pang, Wenjing Sun, Jingshu Geng, Nan Wu, Yuhui Wang, Dandan Tong, Yan Jin, Songbin Fu

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, Colorectal cancer, Gene Expression, migration, Metastasis, Ectopic Gene Expression, 0302 clinical medicine, Cell Movement, Medicine, Neoplasm Metastasis, MMP-2, TRIB1, Intracellular Signaling Peptides and Proteins, Cell migration, Middle Aged, invasion, src-Family Kinases, Oncology, 030220 oncology & carcinogenesis, Matrix Metalloproteinase 2, Female, Colorectal Neoplasms, Proto-oncogene tyrosine-protein kinase Src, Research Paper, Adult, MAP Kinase Signaling System, Protein Serine-Threonine Kinases, 03 medical and health sciences, colorectal carcinoma, Cell Line, Tumor, Cell Adhesion, Gene silencing, Humans, neoplasms, Aged, Cell Proliferation, Neoplasm Staging, Oncogene, business.industry, Gene Amplification, Cancer, medicine.disease, digestive system diseases, 030104 developmental biology, Focal Adhesion Kinase 1, Cancer research, Neoplasm Grading, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5084566612368ae15d583e9fcaa6c0Test
http://europepmc.org/articles/PMC5564616Test

5

ROR1 expression as a biomarker for predicting prognosis in patients with colorectal cancer

المؤلفون: Jian-Kang Zhou, Chenglin Guo, Lunxu Liu, Xuesha Liu, Yu-Zhu Zheng, Qiheng Gou, Carlo M. Croce, Yong Peng, Rui Ma

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Oncology, Adult, Male, medicine.medical_specialty, Pathology, Colorectal cancer, colorectal cancer, Kaplan-Meier Estimate, Receptor Tyrosine Kinase-like Orphan Receptors, Metastasis, receptor-tyrosine-kinase-like orphan receptor 1, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Thoracic Oncology, medicine, Biomarkers, Tumor, Humans, prognostic factor, Survival analysis, Aged, Neoplasm Staging, Aged, 80 and over, Tissue microarray, tissue microarray, business.industry, Proportional hazards model, Cancer, Middle Aged, medicine.disease, Prognosis, Up-Regulation, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 030220 oncology & carcinogenesis, Lymphatic Metastasis, immunohistochemistry, Biomarker (medicine), Female, business, Colorectal Neoplasms, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a706d4787ef6529236eeb667834529Test
http://europepmc.org/articles/PMC5464834Test

6

Identification of DBCCR1 as a suppressor in the development of lung cancer that is associated with increased DNA methyltransferase 1

المؤلفون: Jinjun Ye, Jingyuan Zhang, Ying Fang, Jifeng Feng, Guoren Zhou, Zhi Zhang, Lei Sun

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Adult, DNA (Cytosine-5-)-Methyltransferase 1, Male, Lung Neoplasms, tumor suppressor, DNA methyltransferase, Down-Regulation, Cell Cycle Proteins, Nerve Tissue Proteins, Epigenesis, Genetic, 03 medical and health sciences, 0302 clinical medicine, Cell Movement, Cell Line, Tumor, medicine, Humans, Epigenetics, Lung cancer, Aged, Neoplasm Staging, Bladder cancer, epigenetics, business.industry, DBCCR1, Tumor Suppressor Proteins, Cancer, DNA Methylation, Middle Aged, medicine.disease, Survival Analysis, Up-Regulation, Gene Expression Regulation, Neoplastic, lung cancer, 030104 developmental biology, Oncology, Tumor progression, A549 Cells, 030220 oncology & carcinogenesis, DNA methylation, Cancer cell, DNMT1, Cancer research, CpG Islands, Female, business, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c54318690853f93a896eec662433b9c1Test
http://europepmc.org/articles/PMC5464830Test

7

Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX

المؤلفون: Aesun Shin, Seong Geun Kim, Jung Ah Hwang, Seung-Hyun Hong, Yeon-Su Lee, Hyuk Chan Kwon, Sung Yong Oh

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Oncology, Male, Organoplatinum Compounds, medicine.medical_treatment, Leucovorin, Kaplan-Meier Estimate, polymorphism, Receptor, IGF Type 1, Insulin-like growth factor, 0302 clinical medicine, FOLFOX, Gene Frequency, Antineoplastic Combined Chemotherapy Protocols, Insulin-Like Growth Factor I, education.field_of_study, Hazard ratio, Middle Aged, Oxaliplatin, Treatment Outcome, 030220 oncology & carcinogenesis, Female, Fluorouracil, medicine.drug, Research Paper, Adult, medicine.medical_specialty, Genotype, Population, Single-nucleotide polymorphism, Polymorphism, Single Nucleotide, insulin-like growth factor, 03 medical and health sciences, Young Adult, Stomach Neoplasms, Internal medicine, medicine, Humans, Genetic Predisposition to Disease, education, Aged, Gynecology, Chemotherapy, business.industry, gastric cancer, Cancer, Receptors, Somatomedin, medicine.disease, 030104 developmental biology, Multivariate Analysis, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7233e8362870f42755d3f08d630e23b9Test
http://europepmc.org/articles/PMC5058750Test

8

EZH2 promotes cell migration and invasion but not alters cell proliferation by suppressing E-cadherin, partly through association with MALAT-1 in pancreatic cancer

المؤلفون: Weifeng Song, Feng Jiao, Liwei Wang, Lei Wang, Ting Han, Cuncun Yuan, Hai Hu, Ziliang Jin

المصدر: Oncotarget

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Pathology, medicine.medical_specialty, cell migration, pancreatic cancer, enhancer of zeste homolog 2, macromolecular substances, Kaplan-Meier Estimate, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Antigens, CD, Cell Movement, Pancreatic cancer, medicine, Gene silencing, Humans, Enhancer of Zeste Homolog 2 Protein, Neoplasm Invasiveness, Aged, Cell Proliferation, Gene knockdown, long non-coding RNA, Cell growth, business.industry, EZH2, Cancer, Middle Aged, medicine.disease, Cadherins, metastasis associated lung adenocarcinoma transcript 1, Gene Expression Regulation, Neoplastic, Pancreatic Neoplasms, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Adenocarcinoma, Female, RNA, Long Noncoding, business, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8b579ff2f7f4eb649def047aeedc6fTest
http://europepmc.org/articles/PMC4905466Test

9

Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC

المؤلفون: Silvia Basato, Andromachi Kotsafti, Francesca Erroi, Ignazio Castagliuolo, Melania Scarpa, Renata D'Incà, Carlo Castoro, Massimo Rugge, Paola Brun, Imerio Angriman, Marco Scarpa

المصدر: Oncotarget

مصطلحات موضوعية: Male, Colorectal cancer, Carcinogenesis, Gastroenterology, DNA Methyltransferase 3A, 0302 clinical medicine, Intestinal mucosa, Surgical oncology, DNA (Cytosine-5-)-Methyltransferases, Intestinal Mucosa, Promoter Regions, Genetic, DNA Modification Methylases, Middle Aged, Cadherins, Ulcerative colitis, Oncology, 030220 oncology & carcinogenesis, DNA methylation, Colonic Neoplasms, Adenocarcinoma, 030211 gastroenterology & hepatology, Female, MutL Protein Homolog 1, Research Paper, Adult, DNA (Cytosine-5-)-Methyltransferase 1, medicine.medical_specialty, Adolescent, Colon, Adenomatous Polyposis Coli Protein, 03 medical and health sciences, Young Adult, Internal medicine, medicine, Biomarkers, Tumor, Humans, RNA, Messenger, Aged, APC, Biomarker, Promoter methylation, business.industry, Tumor Suppressor Proteins, Cancer, DNA Methylation, medicine.disease, digestive system diseases, Core Binding Factor Alpha 3 Subunit, DNA Repair Enzymes, Dysplasia, Colitis, Ulcerative, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4fd9027568ef04fcd4412c201fb273Test
http://hdl.handle.net/11577/3187226Test

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