كتاب
Network Meta-Analysis
| العنوان: | Network Meta-Analysis |
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| المؤلفون: | Watt J., Del Giovane C. |
| المساهمون: | Watt, J., Del Giovane, C. |
| بيانات النشر: | Humana Press Inc. |
| سنة النشر: | 2022 |
| المجموعة: | Archivio della ricerca dell'Università di Modena e Reggio Emilia (Unimore: IRIS) |
| مصطلحات موضوعية: | Consistency, Direct treatment comparison, Homogeneity, Indirect treatment comparison, Mixed treatment comparison, Network connectivity, Network meta-analysi, Pairwise meta-analysi, Systematic review, Transitivity |
| الوصف: | There are often multiple potential interventions to treat a disease; therefore, we need a method for simultaneously comparing and ranking all of these available interventions. In contrast to pairwise meta-analysis, which allows for the comparison of one intervention to another based on head-to-head data from randomized trials, network meta-analysis (NMA) facilitates simultaneous comparison of the efficacy orsafety of multiple interventions that may not have been directly compared in a randomized trial. NMAs help researchers study important and previously unanswerable questions, which have contributed to a rapid rise in the number of NMA publications in the biomedical literature. However, the conduct and interpretation of NMAs are more complex than pairwise meta-analyses: there are additional NMA model assumptions (i.e., network connectivity, homogeneity, transitivity, and consistency) and outputs (e.g., network plots and surface under the cumulative ranking curves [SUCRAs]). In this chapter, we will: (1) explore similarities and differences between pairwise and network meta-analysis; (2) explain the differences between direct, indirect, and mixed treatment comparisons; (3) describe how treatment effects are derived from NMA models; (4) discuss key criteria predicating completion of NMA; (5) interpret NMA outputs; (6) discuss areas of ongoing methodological research in NMA; (7) outline an approach to conducting a systematic review and NMA; (8) describe common problems that researchers encounter when conducting NMAs and potential solutions; and (9) outline an approach to critically appraising a systematic review and NMA. |
| نوع الوثيقة: | book part |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/isbn/978-1-0716-1565-2; info:eu-repo/semantics/altIdentifier/isbn/978-1-0716-1566-9; info:eu-repo/semantics/altIdentifier/pmid/34550592; ispartofbook:Methods in Molecular Biology; volume:2345; firstpage:187; lastpage:201; serie:METHODS IN MOLECULAR BIOLOGY; http://hdl.handle.net/11380/1279449Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85116093437 |
| DOI: | 10.1007/978-1-0716-1566-9_12 |
| الإتاحة: | https://doi.org/10.1007/978-1-0716-1566-9_12Test http://hdl.handle.net/11380/1279449Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.96604F5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/978-1-0716-1566-9_12 |
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