دورية أكاديمية
Minimally Invasive Methods for Staging in Lung Cancer: Systematic Review and Meta-Analysis
| العنوان: | Minimally Invasive Methods for Staging in Lung Cancer: Systematic Review and Meta-Analysis |
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| المؤلفون: | Labarca, Gonzalo, Aravena, Carlos, Ortega, Francisco, Arenas, Alex, Majid, Adnan, Folch, Erik, Mehta, Hiren, Jantz, Michael, Fernández-Bussy, Sebastián |
| بيانات النشر: | Hindawi Publishing Corp. |
| سنة النشر: | 2016 |
| المجموعة: | Repositorio Universidad del Desarrollo (UDD) |
| مصطلحات موضوعية: | Endobronchial ultrasound (EBUS), Endoscopic ultrasound (EUS), Mediastinal staging, meta-analysis |
| الوصف: | Introduction. Endobronchial ultrasound (EBUS) is a procedure that provides access to the mediastinal staging; however, EBUS cannot be used to stage all of the nodes in the mediastinum. In these cases, endoscopic ultrasound (EUS) is used for complete staging. Objective. To provide a synthesis of the evidence on the diagnostic performance of EBUS + EUS in patients undergoing mediastinal staging. Methods. Systematic review and meta-analysis to evaluate the diagnostic yield of EBUS + EUS compared with surgical staging. Two researchers performed the literature search, quality assessments, data extractions, and analyses. We produced a meta-analysis including sensitivity, specificity, and likelihood ratio analysis. Results. Twelve primary studies (1515 patients) were included; two were randomized controlled trials (RCTs) and ten were prospective trials. The pooled sensitivity for combined EBUS + EUS was 87% (CI 84–89%) and the specificity was 99% (CI 98–100%). For EBUS + EUS performed with a single bronchoscope group, the sensitivity improved to 88% (CI 83.1–91.4%) and specificity improved to 100% (CI 99-100%). Conclusion. EBUS + EUS is a highly accurate and safe procedure. The combined procedure should be considered in selected patients with lymphadenopathy noted at stations that are not traditionally accessible with conventional EBUS. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | Labarca G, Aravena C, Ortega F, Arenas A, Majid A, Folch E, Mehta HJ, Jantz MA, Fernandez-Bussy S. Minimally Invasive Methods for Staging in Lung Cancer: Systematic Review and Meta-Analysis. Pulm Med. 2016;2016:1024709.; http://hdl.handle.net/11447/1544Test; http://dx.doi.org/10.1155/2016/1024709Test |
| DOI: | 10.1155/2016/1024709 |
| الإتاحة: | https://doi.org/10.1155/2016/1024709Test http://hdl.handle.net/11447/1544Test |
| رقم الانضمام: | edsbas.B0E29061 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1155/2016/1024709 |
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