دورية أكاديمية
Effects and Mechanisms of Five Psoralea Prenylflavonoids on Aging-Related Diseases
| العنوان: | Effects and Mechanisms of Five Psoralea Prenylflavonoids on Aging-Related Diseases |
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| المؤلفون: | Yi-Ting Zhou, Lin Zhu, Yunyun Yuan, Shuang Ling, Jin-Wen Xu |
| المصدر: | Oxidative Medicine and Cellular Longevity, Vol 2020 (2020) |
| بيانات النشر: | Hindawi Limited |
| سنة النشر: | 2020 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Cytology, QH573-671 |
| الوصف: | During the aging process, senescent cells gradually accumulate in the organs; they secrete proinflammatory cytokines and other factors, collectively known as the senescence-associated secretory phenotype (SASP). SASP secretions contribute to “inflammaging,” which is a state of chronic, systemic, sterility, low-grade inflammatory microenvironment and a key risk factor in the development of aging-related diseases. Fructus psoraleae is a traditional Chinese medical herb best known for delaying aging and treating osteoporosis. Prenylflavonoids from fructus psoraleae are the main bioactive compounds responsible for its pharmacological applications, such as beaching, bavachinin, bavachalcone, isobavachalcone, and neobavaisoflavone. In previous decades, there have been some promising studies on the pharmacology of fructus psoraleae. Here, we focus on the anti-inflammatory and antiaging diseases of five psoralea prenylflavonoids, such as cardiovascular protection, diabetes and obesity intervention, neuroprotection, and osteoporosis, and discuss the mechanism of these active ingredients for better understanding the material basis and drug application of fructus psoraleae in Chinese medicine. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1942-0900 1942-0994 |
| العلاقة: | http://dx.doi.org/10.1155/2020/2128513Test; https://doaj.org/toc/1942-0900Test; https://doaj.org/toc/1942-0994Test; https://doaj.org/article/44518d194ba04c62be5ebe52c7282c53Test |
| DOI: | 10.1155/2020/2128513 |
| الإتاحة: | https://doi.org/10.1155/2020/2128513Test https://doaj.org/article/44518d194ba04c62be5ebe52c7282c53Test |
| رقم الانضمام: | edsbas.91C004B9 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 19420900 19420994 |
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| DOI: | 10.1155/2020/2128513 |