دورية أكاديمية
Development and Validation of a Spike Detection and Classification Algorithm Aimed at Implementation on Hardware Devices
| العنوان: | Development and Validation of a Spike Detection and Classification Algorithm Aimed at Implementation on Hardware Devices |
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| المؤلفون: | E. Biffi, D. Ghezzi, A. Pedrocchi, G. Ferrigno |
| المصدر: | Computational Intelligence and Neuroscience, Vol 2010 (2010) |
| بيانات النشر: | Hindawi Limited |
| سنة النشر: | 2010 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Computer applications to medicine. Medical informatics, R858-859.7, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| الوصف: | Neurons cultured in vitro on MicroElectrode Array (MEA) devices connect to each other, forming a network. To study electrophysiological activity and long term plasticity effects, long period recording and spike sorter methods are needed. Therefore, on-line and real time analysis, optimization of memory use and data transmission rate improvement become necessary. We developed an algorithm for amplitude-threshold spikes detection, whose performances were verified with (a) statistical analysis on both simulated and real signal and (b) Big O Notation. Moreover, we developed a PCA-hierarchical classifier, evaluated on simulated and real signal. Finally we proposed a spike detection hardware design on FPGA, whose feasibility was verified in terms of CLBs number, memory occupation and temporal requirements; once realized, it will be able to execute on-line detection and real time waveform analysis, reducing data storage problems. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1687-5265 1687-5273 |
| العلاقة: | http://dx.doi.org/10.1155/2010/659050Test; https://doaj.org/toc/1687-5265Test; https://doaj.org/toc/1687-5273Test; https://doaj.org/article/95d68a0e3d554c54abb9bf9ae43f2f3cTest |
| DOI: | 10.1155/2010/659050 |
| الإتاحة: | https://doi.org/10.1155/2010/659050Test https://doaj.org/article/95d68a0e3d554c54abb9bf9ae43f2f3cTest |
| رقم الانضمام: | edsbas.8E732C41 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 16875265 16875273 |
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| DOI: | 10.1155/2010/659050 |