المؤلفون: Feduniw, Stepan¹ (AUTHOR), Krupa, Izabela² (AUTHOR), Łagowska, Katarzyna² (AUTHOR), Laudański, Piotr^3,4,5 (AUTHOR), Tabarkiewicz, Jacek^2,6 (AUTHOR), Stawarz, Barbara⁷ (AUTHOR), Raba, Grzegorz⁸ (AUTHOR)

المصدر: Journal of Pregnancy. 5/7/2024, Vol. 2024, p1-10. 10p.

مصطلحات موضوعية: *CANNABINOID receptors, *PREMATURE labor, *PLACENTA, *GENETIC transcription, *CHILDBIRTH

مستخلص: Background: The cannabinoid receptor (CBR) plays a significant role in oogenesis, pregnancy, and childbirth. It might also play a significant role in preterm birth (PTB). The aim of the study was to investigate the association between the expression of the CBR in the placenta and the incidence of PTB. Methods: This prospective, observational, multicentre preliminary study was conducted on placental samples obtained from 109 women. The study included 95 patients hospitalized due to the high risk of PTB. They were divided into two groups: Group 1, where the expression of the CBR1 and CBR1a was analyzed, and Group 2, in which we examined CBR2 expression. The control group, that is, Group 3, consisted of 14 women who delivered at term, and their placentas were tested for the presence of all three receptor types (CBR1, CBR1a, and CBR2). Results: The study used reverse transcription and real-time PCR methods to assess the expression of CBRs in the placental tissues. The expression of the CBR2, CBR1, and CBR1a receptors was significantly lower in the placentas of women after PTB compared to those after term births, p = 0.038 , 0.033, and 0.034, respectively. Conclusions: The presence of CBR mRNA in the human placental tissue was confirmed. The decreased expression of CBRs could serve as an indicator in predicting PTB. [ABSTRACT FROM AUTHOR]

المؤلفون: Liu, Wei^1,2 (AUTHOR), Wu, Yue^1,2 (AUTHOR), Zhang, Na^3,4 (AUTHOR), Liu, Sijin^1,2 (AUTHOR), Zhou, Li^3,4 (AUTHOR)

المصدر: Disease Markers. 8/22/2022, p1-8. 8p.

مصطلحات موضوعية: *PREMATURE labor, *CHILDBIRTH, *IRON metabolism, *FERRITIN, *TRANSFERRIN, *IRON, *ENZYME-linked immunosorbent assay

مستخلص: Background. Increasing evidence reveals that iron deficiency during pregnancy causes adverse pregnancy outcomes. Thus far, the mechanisms underlying iron deficiency-associated preterm birth are mostly limited to animal studies. Whether the suggested mechanisms exist in human requires further investigation. The goal of this study was to characterize the iron metabolism in both the maternal side and fetal side in pregnant women with preterm birth. Methods. Serum and placenta samples were collected from 42 pregnant women divided into four groups according to the gestational week. Indicators of iron metabolism, including serum iron, serum hepcidin, placental tissue iron, ferroportin (FPN), transferrin receptor 1 (TfR1), and ferritin, were surveyed using enzyme-linked immunosorbent assays (Elisa), Western blots, and real-time quantitative polymerase chain reactions (qRT-PCR). Results. Significant reduction of maternal serum iron was observed in women with preterm birth relative to those with full-term birth, indicative of worsen iron deficiency in those mothers with preterm birth. Meanwhile, the maternal hepcidin levels were notably diminished in women with preterm birth, whereas the fetal hepcidin levels were comparable between the two groups. Moreover, the placental iron stores were remarkably reduced in the preterm group, associated with reduced concentration of TfR1 and increased FPN concentration relative to the normal controls. In other words, the ratio of placental FPN mass to TfR1 mass (PIDI index) was strikingly increased in the preterm group. Conclusions. Dysregulated iron homeostasis in both the maternal and fetal sides was implicated in preterm births, and disordered regulations in maintaining the placental iron equilibrium were also presumed to account for the compromised fetal iron supply. [ABSTRACT FROM AUTHOR]

المؤلفون: Alazmah, Abdulfatah

المصدر: Case Reports in Dentistry; 11/23/2020, p1-5, 5p

مصطلحات موضوعية: MIXED dentition, AMELOGENESIS imperfecta, PREMATURE labor, CHILDBIRTH, CHILD development

مستخلص: Preterm birth children comprise about 6% of live births around the world. It is known that premature children exhibit oral anomalies that could affect the function and/or appearance of their dentition in addition to their medical needs. A diagnosis of amelogenesis imperfecta (AI) can present a challenge for both the patient and the treating clinician. This can be more complicated in the case of child treatment, where cooperation and some of the treatment modalities for adults can not be considered. Conventional management of such children is not possible due to the ongoing process of growth and development and the ability of the child to cope with the extensive and lengthy treatment procedure. This article highlights a minimally invasive method for managing AI using adhesive and full-coverage restoration that requires no tooth preparation; this allows the structural integrity of the teeth to be maintained, along with their vitality. As a result, the child will have teeth with better function and aesthetic, to improve eating, appearance, and self-confidence. [ABSTRACT FROM AUTHOR]

: Copyright of Case Reports in Dentistry is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Giraldo, Paulo César, Araújo, Edilson D., Junior, José Eleutério, do Amaral, Rose Luce Gomes, Passos, Mauro R. L., Gonçalves, Ana Katherine

المصدر: Infectious Diseases in Obstetrics & Gynecology; 2012, p1-4, 4p, 2 Charts

مصطلحات موضوعية: GENITOURINARY organ infections, MATERNAL health, PREMATURE labor, DISEASE prevalence, BACTERIAL vaginitis treatment, CHILDBIRTH

مستخلص: Urogenital infections are extremely prevalent during pregnancy and are an important cause of premature labor. However, the prevalence of urogenital infections during childbirth is not well known. Objective. Identify urogenital infections present at the beginning of labor in both full-term and preterm pregnancies. Study Design. Ninety-four women were admitted to the inpatient maternity clinic of the Federal University of Rio Grande do Norte (UFRN). In total, 49 women in preterm labor and 45 women in full-termlabor were included in the study, and samples of urinary, vaginal, and perianalmaterial were collected formicrobiological analysis. Results. The prevalences of general infections in the preterm labor group and the full-term labor group were 49.0% and 53.3% (P = 0.8300), respectively. Urogenital infections in the preterm and full-term labor groups included urinary tract infection in 36.7% and 22.2% of women, vaginal candidiasis in 20.4% and 28.9% of women, bacterial vaginosis in 34.7% and 28.9% of women, and group B streptococcus in 6.1% and 15.6% of women, respectively. Conclusions. Urogenital infections were prevalent in women in preterm labor and full-term labor; however, significant differences between the groups were not observed. [ABSTRACT FROM AUTHOR]

: Copyright of Infectious Diseases in Obstetrics & Gynecology is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

المؤلفون: Göçmen, Ahmet, Fanlıkan, Fatih

المصدر: Case Reports in Obstetrics & Gynecology; 2013, p1-3, 3p

مصطلحات موضوعية: ROBOTICS, SURGICAL robots, CHILDBIRTH, HEALTH outcome assessment, PREMATURE labor, LAPAROSCOPIC surgery

مستخلص: Introduction. To report the robotic-assisted abdominal cerclage performed in two nonpregnant women and the success of live birth outcomes. Presentation of Cases. A 36-year-old woman with a complaint of recurrent second trimester pregnancy losses and a 35-year-old patient with a complaint of preterm deliveries and cervical insufficiency underwent robotic assisted abdominal cervicoisthmic cerclage placement in nonpregnant period. The two patients had spontaneous pregnancy after the robotic-assisted abdominal cerclage and delivered healthy infants. Discussion. The limitations of traditional laparoscopic abdominal cerclage have been accomplished with robotic surgery advantages especially intuitivemovements and increased range of motion. There are only a few studies in the literature including robotic assisted abdominal cerclage in nonpregnant women, and only five successful live birth outcomes were reported. In this paper, we reported the sixth and seventh cases of achieved live pregnancy after robotic assisted abdominal cerclage in the literature. Conclusion. Robotic assisted abdominal cerclage is a good alternative surgical method with successful pregnancy outcomes. [ABSTRACT FROM AUTHOR]

: Copyright of Case Reports in Obstetrics & Gynecology is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)