Comparison of Globus Pallidus Interna and Subthalamic Nucleus in Deep Brain Stimulation for Parkinson Disease: An Institutional Experience and Review
| العنوان: | Comparison of Globus Pallidus Interna and Subthalamic Nucleus in Deep Brain Stimulation for Parkinson Disease: An Institutional Experience and Review |
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| المؤلفون: | Shilpa Chitnis, Umar Yazdani, Svjetlana Miocinovic, Richard B. Dewey, Neepa Patel, Shazia Mirza |
| المصدر: | Parkinson's Disease, Vol 2017 (2017) Parkinson's Disease |
| بيانات النشر: | Hindawi Limited, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | medicine.medical_specialty, Parkinson's disease, Deep brain stimulation, medicine.medical_treatment, Neuroscience (miscellaneous), Review Article, Disease, Multidisciplinary team, lcsh:RC346-429, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, Quality of life (healthcare), medicine, In patient, 030212 general & internal medicine, lcsh:Neurology. Diseases of the nervous system, business.industry, medicine.disease, nervous system diseases, Psychiatry and Mental health, Subthalamic nucleus, nervous system, Neurology (clinical), business, 030217 neurology & neurosurgery, Globus pallidus interna |
| الوصف: | Deep Brain Stimulation (DBS) has revolutionized the lives of patients of Parkinson disease, offering therapeutic options to those not benefiting entirely from medications alone. With its proven track record of outperforming the best medical management, the goal is to unlock the full potential of this therapy. Currently, the Globus Pallidus Interna (GPi) and Subthalamic Nucleus (STN) are both viable targets for DBS, and the choice of site should focus on the constellation of symptoms, both motor and nonmotor, which are key determinants to quality of life. Our article sheds light on the specific advantages and drawbacks of the two sites, highlighting the need for matching the inherent properties of a target with specific desired effects in patients. UT Southwestern Medical Center has a robust and constantly evolving DBS program and the narrative from our center provides invaluable insight into the practical realities of DBS. The ultimate decision in selecting a DBS target is complex, ideally made by a multidisciplinary team, tailored towards each patient’s profile and their expectations, by drawing upon scientific evidence coupled with experience. Ongoing research is expanding our knowledge base, which should be dynamically incorporated into an institute’s DBS paradigm to ensure that patients receive the optimal therapy. |
| تدمد: | 2042-0080 2090-8083 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ff641fbe743dcf8a28b3b4816d9c94Test https://doi.org/10.1155/2017/3410820Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....01ff641fbe743dcf8a28b3b4816d9c94 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20420080 20908083 |
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