رسالة جامعية
Mechanisms Governing Mesothelial Clearance by Ovarian Cancer Spheroids
| العنوان: | Mechanisms Governing Mesothelial Clearance by Ovarian Cancer Spheroids |
|---|---|
| المؤلفون: | Davidowitz, Rachel Alexis |
| مرشدي الرسالة: | Brugge, Joan S. |
| بيانات النشر: | Harvard University, 2013. |
| سنة النشر: | 2013 |
| المجموعة: | Harvard University |
| Original Material: | Davidowitz, Rachel Alexis. 2013. Mechanisms Governing Mesothelial Clearance by Ovarian Cancer Spheroids. Doctoral dissertation, Harvard University. |
| مصطلحات موضوعية: | Cellular biology, Biology, Cancer, mesothelium, Metastasis, Ovarian |
| الوصف: | Metastatic dissemination of ovarian tumors involves the invasion of multi-cellular tumor cell clusters into the mesothelial cell lining of organs in the peritoneal cavity. We developed an in vitro assay that models this initial step of ovarian cancer metastasis to investigate the mechanisms of invasion. Pre-clustered ovarian cancer multicellular spheroids are incubated with GFP-expressing mesothelial monolayers and the extent of mesothelial invasion is monitored by time-lapse video microscopy. |
| Original Identifier: | oai:dash.harvard.edu:1/11157454 |
| نوع الوثيقة: | Thesis or Dissertation |
| الإتاحة: | http://dissertations.umi.com/gsas.harvard:10719Test http://nrs.harvard.edu/urn-3:HUL.InstRepos:11157454Test |
| رقم الانضمام: | edsndl.harvard.edu.oai.dash.harvard.edu.1.11157454 |
| قاعدة البيانات: | Networked Digital Library of Theses & Dissertations |
| الوصف غير متاح. |