المؤلفون: Mustafá, Emilio, Cordisco González, Santiago, Damian, Marjorie, Cantel, Sonia, Denoyelle, Severine, Wagner, Renaud, Schiöth, Helgi, Fehrentz, Jean-Alain, Banères, Jean-Louis, Perelló, Mario, Raingo, Jesica

المساهمون: Instituto Multidisciplinario de Biología Celular La Plata (IMBICE), Consejo Nacional de Investigaciones Científicas y Técnicas Buenos Aires (CONICET)-Universidad Nacional de la Plata Argentine (UNLP)-Comisión de Investigaciones Científicas Buenos Aires (CIC), Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Uppsala University Hospital, Sechenov First Moscow State Medical University

المصدر: ISSN: 1663-9812 ; Frontiers in Pharmacology ; https://hal.science/hal-03382623Test ; Frontiers in Pharmacology, 2021, 12, pp.712437. ⟨10.3389/fphar.2021.712437⟩.

مصطلحات موضوعية: Cav2.2, GPCR, Constitutive activity, Dopamine receptor, Ghrelin receptor, Heterodimerization, [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34447311; hal-03382623; https://hal.science/hal-03382623Test; https://hal.science/hal-03382623/documentTest; https://hal.science/hal-03382623/file/fphar-12-712437.pdfTest; PUBMED: 34447311; PUBMEDCENTRAL: PMC8383165

الإتاحة: https://doi.org/10.3389/fphar.2021.712437Test
https://hal.science/hal-03382623Test
https://hal.science/hal-03382623/documentTest
https://hal.science/hal-03382623/file/fphar-12-712437.pdfTest

المؤلفون: Zindel, Diana, Mensat, Patrick, Vol, Claire, Homayed, Zeinab, Charrier‐savournin, Fabienne, Trinquet, Eric, Banères, Jean‐louis, Pin, Jean-Philippe, Pannequin, Julie, Roux, Thomas, Dupuis, Elodie, Prézeau, Laurent

المساهمون: Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Cisbio Bioassays, Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0892-6638.

مصطلحات موضوعية: inverse agonist, constitutive activity, cellular signaling, Hippo pathway, Ghrelin receptor, MESH: Activating Transcription Factor 6, MESH: Cell Cycle Proteins, MESH: Receptors, G-Protein-Coupled, MESH: Transcription Factors, MESH: GTP-Binding Protein alpha Subunits, G12-G13, Gq-G11, MESH: Gene Expression Regulation, MESH: HEK293 Cells, MESH: Humans, MESH: Phosphorylation, MESH: Protein-Serine-Threonine Kinases, [SDV]Life Sciences [q-bio], [SDV.BC]Life Sciences [q-bio]/Cellular Biology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34114695; hal-03263933; https://hal.science/hal-03263933Test; https://hal.science/hal-03263933/documentTest; https://hal.science/hal-03263933/file/211118-Zindel-FASEB%20J-2021-HAL%20%281%29.pdfTest; PUBMED: 34114695

الإتاحة: https://doi.org/10.1096/fj.202002159RTest
https://hal.science/hal-03263933Test
https://hal.science/hal-03263933/documentTest
https://hal.science/hal-03263933/file/211118-Zindel-FASEB%20J-2021-HAL%20%281%29.pdfTest

المؤلفون: Chebani, Yacine, Marion, Candice, Zizzari, Philippe, Chettab, Khadidja, Pastor, Marie, Korostelev, Marie, Geny, David, Epelbaum, Jacques, Tolle, Virginie, Morisset-Lopez, Séverine, Pantel, Jacques

المساهمون: Centre de Psychiatrie et Neurosciences (U894), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Mécanismes Adaptatifs et Evolution (MECADEV), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Centre de biophysique moléculaire (CBM), Université d'Orléans (UO)-Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Vanderbilt University School of Medicine Nashville, INSERM et FRM-Institut Danone

المصدر: ISSN: 1937-9145.

مصطلحات موضوعية: Obesity, Ghrelin/physiology, Arrestin, Ghrelin receptor, Mutation Analysis, G protein coupled receptor GPCR, Phosphorylation sites, Food intake, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/27095593; inserm-01463897; https://inserm.hal.science/inserm-01463897Test; https://inserm.hal.science/inserm-01463897/documentTest; https://inserm.hal.science/inserm-01463897/file/aae0374_ArticleContent_v13_proofs_FOR%20HAL.pdfTest; PUBMED: 27095593

الإتاحة: https://doi.org/10.1126/scisignal.aae0374Test
https://inserm.hal.science/inserm-01463897Test
https://inserm.hal.science/inserm-01463897/documentTest
https://inserm.hal.science/inserm-01463897/file/aae0374_ArticleContent_v13_proofs_FOR%20HAL.pdfTest

المؤلفون: Mear, Yves, Enjalbert, Alain, Thirion, Sylvie

المساهمون: Centre de recherche en neurobiologie - neurophysiologie de Marseille (CRN2M), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 1662-4548.

مصطلحات موضوعية: ghrelin receptor, GPCR, constitutive activity, signaling pathway, PLC, β-arrestin, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/23754971; hal-00966209; https://hal.science/hal-00966209Test; https://hal.science/hal-00966209/documentTest; https://hal.science/hal-00966209/file/fnins-07-00087.pdfTest; PUBMED: 23754971

الإتاحة: https://doi.org/10.3389/fnins.2013.00087Test
https://hal.science/hal-00966209Test
https://hal.science/hal-00966209/documentTest
https://hal.science/hal-00966209/file/fnins-07-00087.pdfTest

المؤلفون: Garcia, Edwin, Heude, Barbara, Petry, Clive, Gueorguiev, Maria, Hassan-Smith, Zaki, Spanou, Antigoni, Ring, Susan, Dunger, David, Wareham, Nicholas, Sandhu, Manjinder, Ong, Ken, Korbonits, Marta

المساهمون: Department of Endocrinology, John Vane Science Center-Barts and the London Medical School, Medical Research Concil Epidemiology Unit, Institute of Medical Science, Recherche en épidémiologie et biostatistique, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), Faculté de médecine, Université Paris-Sud - Paris 11 (UP11), Department of Paediatrics, University of Cambridge UK (CAM), Department of Social Medicine, University of Bristol Bristol

المصدر: ISSN: 0021-972X.

مصطلحات موضوعية: ghrelin receptor, body mass index, ghrelin, gene, growth, ALSPAC, Ely Study, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/18647811; inserm-00311659; https://www.hal.inserm.fr/inserm-00311659Test; https://www.hal.inserm.fr/inserm-00311659/documentTest; https://www.hal.inserm.fr/inserm-00311659/file/PapierEPubEhead.pdfTest; https://www.hal.inserm.fr/inserm-00311659/file/inserm-00311659_edited.pdfTest; PUBMED: 18647811

الإتاحة: https://doi.org/10.1210/jc.2008-0366Test
https://www.hal.inserm.fr/inserm-00311659Test
https://www.hal.inserm.fr/inserm-00311659/documentTest
https://www.hal.inserm.fr/inserm-00311659/file/PapierEPubEhead.pdfTest
https://www.hal.inserm.fr/inserm-00311659/file/inserm-00311659_edited.pdfTest

المؤلفون: Maingot, Mathieu, Blayo, Anne-Laure, Denoyelle, Severine, M’kadmi, Céline, Damian, Marjorie, Mary, Sophie, Gagne, Didier, Sanchez, Pierre, Aicher, Babette, Schmidt, Peter, Müller, Gilbert, Teifel, Michael, Günther, Eckhard, Marie, Jacky, Banères, Jean-Louis, Martinez, Jean, Fehrentz, Jean-Alain

المساهمون: Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Aeterna-Zentaris

المصدر: ISSN: 0960-894X ; Bioorganic and Medicinal Chemistry Letters ; https://hal.science/hal-02871896Test ; Bioorganic and Medicinal Chemistry Letters, 2016, 26 (10), pp.2408-2412. ⟨10.1016/j.bmcl.2016.04.003⟩.

مصطلحات موضوعية: Antagonist, Chirality, Ghrelin receptor (GHS-R1a), Inverse agonist, Structural modulation, 1 2 4-Triazole scaffold, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/27072910; hal-02871896; https://hal.science/hal-02871896Test; PUBMED: 27072910

الإتاحة: https://doi.org/10.1016/j.bmcl.2016.04.003Test
https://hal.science/hal-02871896Test

المؤلفون: Blayo, Anne-Laure, Maingot, Mathieu, Aicher, Babette, M'Kadmi, Céline, Schmidt, Peter, Müller, Gilbert, Teifel, Michael, Günhter, Eckhard, Gagne, Didier, Denoyelle, Séverine, Martinez, Jean, Fehrentz, Jean-Alain

المساهمون: Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Aeterna-Zentaris, Grant BDI021121

المصدر: ISSN: 0960-894X ; Bioorganic and Medicinal Chemistry Letters ; https://hal.science/hal-01090274Test ; Bioorganic and Medicinal Chemistry Letters, 2015, 25 (1), pp.20-24. ⟨10.1016/j.bmcl.2014.11.031⟩ ; http://www.sciencedirect.com/science/article/pii/S0960894X14012153Test.

مصطلحات موضوعية: 4-Triazole scaffold, Structural modulation, GHS-R1a, ghrelin receptor, Antagonists, SAR study, [CHIM.ORGA]Chemical Sciences/Organic chemistry

العلاقة: hal-01090274; https://hal.science/hal-01090274Test

الإتاحة: https://doi.org/10.1016/j.bmcl.2014.11.031Test
https://hal.science/hal-01090274Test

المؤلفون: Céline M'Kadmi, Peter Schmidt, Eckhard Günther, Anne-Laure Blayo, Mathieu Maingot, Michael Teifel, Jean Martinez, Gilbert Müller, Babette Aicher, Jean-Alain Fehrentz, Didier Gagne, Séverine Denoyelle

المساهمون: Institut des Biomolécules Max Mousseron [Pôle Chimie Balard] (IBMM), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), AEterna Zentaris Gmbh, Grant BDI021121

المصدر: Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2015, 25 (1), pp.20-24. ⟨10.1016/j.bmcl.2014.11.031⟩

مصطلحات موضوعية: ghrelin receptor, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Growth hormone, 01 natural sciences, Biochemistry, GHS-R1a, Cell Line, Structural modulation, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Drug Discovery, Pyridine, Moiety, Animals, Humans, Receptor, Receptors, Ghrelin, Molecular Biology, 030304 developmental biology, 0303 health sciences, 010405 organic chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Organic Chemistry, 4-Triazole scaffold, Biological activity, Triazoles, In vitro, 0104 chemical sciences, 3. Good health, SAR study, chemistry, Molecular Medicine, Ghrelin, Antagonists, Lead compound, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4361224b8765441c6dfbe5027681ad5eTest
https://hal.archives-ouvertes.fr/hal-01090274Test

المؤلفون: Bibian, Mathieu, Blayo, Anne-Laure, Moulin, Aline, Martinez, Jean, Fehrentz, Jean-Alain

المساهمون: Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0040-4039.

مصطلحات موضوعية: heterocycles, silver, 4-triazole, scale-up, enantiopure, pharmacological in-vitro, ghrelin receptor, vivo evaluations, triazole derivatives, inhibitors, antagonists, ligands, [CHIM.ORGA]Chemical Sciences/Organic chemistry

الوقت: 0040-4039

العلاقة: hal-00485739; https://hal.science/hal-00485739Test

الإتاحة: https://doi.org/10.1016/j.tetlet.2010.03.037Test
https://hal.science/hal-00485739Test

المؤلفون: Moulin, Aline, Demange, L., Ryan, J., M'Kadmi, Celine, Galleyrand, Jean-Claude, Martinez, Jean, Fehrentz, Jean-Alain

المساهمون: Institut des Biomolécules Max Mousseron Pôle Chimie Balard (IBMM), Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0960-894X ; Bioorganic and Medicinal Chemistry Letters ; https://hal.science/hal-00420056Test ; Bioorganic and Medicinal Chemistry Letters, 2008, 18 (1), pp.164-168. ⟨10.1016/j.bmcl.2007.10.113⟩.

مصطلحات موضوعية: bond, agonist, antagonist, ghrelin, growth-hormone secretagogue, peptide, ghs-rla, 4-triazole, trisubstituted 1, 4-triazoles, ghrelin receptor ligands, [CHIM.ORGA]Chemical Sciences/Organic chemistry

العلاقة: hal-00420056; https://hal.science/hal-00420056Test

الإتاحة: https://doi.org/10.1016/j.bmcl.2007.10.113Test
https://hal.science/hal-00420056Test