يعرض 1 - 10 نتائج من 5,615 نتيجة بحث عن '"GROWTH FACTOR"', وقت الاستعلام: 1.04s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Different EGF ‐induced receptor dimer conformations for signaling and internalization

    المؤلفون: Haubrich, Jordi, Zwier, Jurriaan, Charrier-Savournin, Fabienne, Prézeau, Laurent, Pin, Jean‐philippe

    المساهمون: Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Cisbio Bioassays Codolet, France (Innovation Management / CbB), ANR-18-CE11-0004,DynaMuR2,Dynamique structurale d'un RCPG dimérique en molécule unique(2018), ANR-10-LABX-0053,MAbImprove,Optimization of therapeutic monoclonal antibodies development Better antibodies, better developed AND better used(2010)

    المصدر: ISSN: 0892-6638.

    مصطلحات موضوعية: TK inhibitors, activation, conformation, epidermal growth factor receptor, internalization, [SDV]Life Sciences [q-bio], [SDV.BC]Life Sciences [q-bio]/Cellular Biology, [SDV.CAN]Life Sciences [q-bio]/Cancer

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38071470; hal-04472295; https://hal.science/hal-04472295Test; https://hal.science/hal-04472295/documentTest; https://hal.science/hal-04472295/file/Haubrich%20Article%20EGFR%20FASEBJ2024.pdfTest; PUBMED: 38071470

    الإتاحة: https://doi.org/10.1096/fj.202301209RTest
    https://hal.science/hal-04472295Test
    https://hal.science/hal-04472295/documentTest
    https://hal.science/hal-04472295/file/Haubrich%20Article%20EGFR%20FASEBJ2024.pdfTest

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  2. 2
    دورية أكاديمية
    Clinical and molecular analysis of lung cancers associated with fibrosing interstitial lung disease

    المؤلفون: Héluain, Valentin, Prévot, Grégoire, Cabarrou, Bastien, Calvayrac, Olivier, Taranchon- Clermont, Estelle, Didier, Alain, Tabourier-Gouin, Sandrine, Milia, Julie, Mazières, Julien

    المساهمون: Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: EISSN: 2590-0412 ; Respiratory Medicine and Research ; https://cnrs.hal.science/hal-04308863Test ; Respiratory Medicine and Research, 2023, 83, pp.100946. ⟨10.1016/j.resmer.2022.100946⟩

    مصطلحات موضوعية: IPF, Idiopathic Pulmonary Fibrosis, CTD-ILD, ILD associated with Connective Tissue Disease, SSC, Systemic Sclerosis, UIP, Usual Interstitial Pneumonia, NSIP, Non-Specific Interstitial Pneumonia, CI, Confidence Interval, NR, Not Reached, TMB, Tumour Mutational Burden, TGF-b, Transforming Growth Factor beta, PDGFR, Platelet Derived Growth Factor Receptor, FGFR, Fibroblast Growth Factor Receptor, EGFR, Epidermal Growth Factor Receptor, MAPK, Mitogen Activated Protein Kinases, ERBB2, Erythroblastic Oncogene B2, PI3K/AKT, Phosphoinositide 3 Kinase/Protein Kinase B

    العلاقة: hal-04308863; https://cnrs.hal.science/hal-04308863Test; https://cnrs.hal.science/hal-04308863/documentTest; https://cnrs.hal.science/hal-04308863/file/Clinical%20and%20Molecular%20Analysis%20of%20Lung%20cancers%20associated%20with%20fibrosing%20interstitial%20lung%20disease_non-edited.pdfTest

    الإتاحة: https://doi.org/10.1016/j.resmer.2022.100946Test
    https://cnrs.hal.science/hal-04308863Test
    https://cnrs.hal.science/hal-04308863/documentTest
    https://cnrs.hal.science/hal-04308863/file/Clinical%20and%20Molecular%20Analysis%20of%20Lung%20cancers%20associated%20with%20fibrosing%20interstitial%20lung%20disease_non-edited.pdfTest

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  3. 3
    دورية أكاديمية
    Acromegalic Cardiomyopathy: An Entity on its own? The Effects of GH and IGF-I Excess and Treatment on Cardiovascular Risk Factors

    المؤلفون: Wolf, Peter, Maione, Luigi, Kamenický, Peter, Chanson, Philippe

    المساهمون: BioTechMed-Graz, Graz University of Technology Graz (TU Graz)-Karl-Franzens-Universität Graz-Medical University Graz, Physiologie et physiopathologie endocriniennes (PHYSENDO), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris-Saclay, Signalisation Hormonale, Physiopathologie Endocrinienne et Métabolique, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hôpital Bicêtre AP-HP, Le Kremlin-Bicêtre, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), AP-HP. Université Paris Saclay

    المصدر: ISSN: 0188-4409 ; Archives of Medical Research ; https://hal.science/hal-04503406Test ; Archives of Medical Research, 2023, 54, ⟨10.1016/j.arcmed.2023.102921⟩.

    مصطلحات موضوعية: Acromegaly Growth hormone Insulin-like growth factor I IGF-I Myocardial hypertrophy Cardiomyopathy Pituitary, Acromegaly, Growth hormone, Insulin-like growth factor I, IGF-I, Myocardial hypertrophy, Cardiomyopathy, Pituitary, [SDV]Life Sciences [q-bio]

    العلاقة: hal-04503406; https://hal.science/hal-04503406Test; https://hal.science/hal-04503406/documentTest; https://hal.science/hal-04503406/file/1-s2.0-S0188440923001595-main.pdfTest

    الإتاحة: https://doi.org/10.1016/j.arcmed.2023.102921Test
    https://hal.science/hal-04503406Test
    https://hal.science/hal-04503406/documentTest
    https://hal.science/hal-04503406/file/1-s2.0-S0188440923001595-main.pdfTest

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  4. 4
    دورية أكاديمية
    Engineering of a Bispecific Nanofitin with Immune Checkpoint Inhibitory Activity Conditioned by the Cross-Arm Binding to EGFR and PDL1

    المؤلفون: Jacquot, Perrine, Muñoz-Garcia, Javier, Fleury, Maurine, Cochonneau, Denis, Gaussin, Rémi, Enouf, Elise, Roze, Caroline, Ollivier, Emilie, Cinier, Mathieu, Heymann, Dominique

    المساهمون: Unité en Sciences Biologiques et Biotechnologies de Nantes (US2B), Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Affilogic SAS, Institut de Cancérologie de l'Ouest Angers/Nantes (UNICANCER/ICO), UNICANCER, AFFILOGIC

    المصدر: ISSN: 2218-273X ; Biomolecules ; https://inserm.hal.science/inserm-04056943Test ; Biomolecules, 2023, 13, ⟨10.3390/biom13040636⟩.

    مصطلحات موضوعية: Jacquot, P. Muñoz-Garcia, J. Fleury, M. Cochonneau, D. Gaussin, R. Enouf, E. Roze, C. Ollivier, E. Cinier, M. Heymann, D epidermal growth factor receptor (EGFR) programmed cell death ligand 1 (PDL1) bispecific Nanofitin tumor specific immune checkpoint inhibitor (ICI), Muñoz-Garcia, Fleury, Cochonneau, Gaussin, Enouf, Roze, Ollivier, Cinier, Heymann, D epidermal growth factor receptor (EGFR), programmed cell death ligand 1 (PDL1), bispecific Nanofitin, tumor specific, immune checkpoint inhibitor (ICI), [SDV]Life Sciences [q-bio]

    العلاقة: inserm-04056943; https://inserm.hal.science/inserm-04056943Test; https://inserm.hal.science/inserm-04056943/documentTest; https://inserm.hal.science/inserm-04056943/file/Jacquot%20et%20al%20Biomolecules%202022.pdfTest

    الإتاحة: https://doi.org/10.3390/biom13040636Test
    https://inserm.hal.science/inserm-04056943Test
    https://inserm.hal.science/inserm-04056943/documentTest
    https://inserm.hal.science/inserm-04056943/file/Jacquot%20et%20al%20Biomolecules%202022.pdfTest

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  5. 5
    دورية أكاديمية
    EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection

    المؤلفون: Capper, David, Reifenberger, Guido, French, Pim, J, Schweizer, Leonille, Weller, Michael, Touat, Mehdi, Niclou, Simone, P, Euskirchen, Philipp, Haberler, Christine, Hegi, Monika, E, Brandner, Sebastian, Le Rhun, Emilie, Rudà, Roberta, Sanson, Marc, Tabatabai, Ghazaleh, Sahm, Felix, Wen, Patrick, Y, Wesseling, Pieter, Preusser, Matthias, van den Bent, Martin, J

    المساهمون: Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: ISSN: 1522-8517.

    مصطلحات موضوعية: Adults, EANO, Guideline, Glioma, Targeted treatments, cancer, central nervous system neoplasms, epidermal growth factor receptors, fibroblast growth factor receptors, neoplasms, braf gene, ros protein, standard of care, cyclin-dependent kinase 4, tumor mutation burden, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36632791; hal-04531041; https://hal.sorbonne-universite.fr/hal-04531041Test; https://hal.sorbonne-universite.fr/hal-04531041/documentTest; https://hal.sorbonne-universite.fr/hal-04531041/file/noad008.pdfTest; PUBMED: 36632791; PUBMEDCENTRAL: PMC10158123

    الإتاحة: https://doi.org/10.1093/neuonc/noad008Test
    https://hal.sorbonne-universite.fr/hal-04531041Test
    https://hal.sorbonne-universite.fr/hal-04531041/documentTest
    https://hal.sorbonne-universite.fr/hal-04531041/file/noad008.pdfTest

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  6. 6
    دورية أكاديمية
    High and low permeability of human pluripotent stem cell–derived blood–brain barrier models depend on epithelial or endothelial features

    المؤلفون: Girard, Stéphane, D, Julien-Gau, Ingrid, Molino, Yves, Combes, Benjamin, F, Greetham, Louise, Khrestchatisky, Michel, Nivet, Emmanuel

    المساهمون: Institut de neurophysiopathologie (INP), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: ISSN: 0892-6638.

    مصطلحات موضوعية: Ac-LDL, acetylated low-density lipoprotein BBB, blood-brain barrier bFGF, basic fibroblast growth factor BMP4, bone morphogenic protein 4 BMVEC, brain microvascular endothelial cells BSA, bovine serum albumin CNS, central nervous system CspA, cyclosporin A EC, endothelial cell ECEM, endothelial cell expansion medium ECIM, endothelial cell induction medium ECM, extracelullar matrix EpC, epithelial cell FPKM, fragment per kilobase million GSK3β, glycogen synthase kinase 3 beta HBMVECs, human brain microvascular endothelial cells hiPSCs, human-induced pluripotent stem cells HUVECs, human umbilical vein endothelial cells LY, lucifer yellow MACS, magnetic activated cell sorting NVU, neurovascular unit Pe, permeability Pr-1, protocol 1 PSCs, pluripotent stem cells RA, retinoic acid RPKM, read per kilobase million TEER, trans-endothelial electrical resistance TGFβ, transforming growth factor beta TNF-α, tumor necrosis factor-alpha UM

    العلاقة: hal-04300615; https://hal.science/hal-04300615Test; https://hal.science/hal-04300615/documentTest; https://hal.science/hal-04300615/file/The%20FASEB%20Journal%20-%202023%20-%20Girard%20-%20High%20and%20low%20permeability%20of%20human%20pluripotent%20stem%20cell%20derived%20blood%20brain%20barrier.pdfTest

    الإتاحة: https://doi.org/10.1096/fj.202201422RTest
    https://hal.science/hal-04300615Test
    https://hal.science/hal-04300615/documentTest
    https://hal.science/hal-04300615/file/The%20FASEB%20Journal%20-%202023%20-%20Girard%20-%20High%20and%20low%20permeability%20of%20human%20pluripotent%20stem%20cell%20derived%20blood%20brain%20barrier.pdfTest

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  7. 7
    تقرير
    The clathrin adaptor AP-1B independently controls proliferation and differentiation in the mammalian intestine

    المؤلفون: Duclos, Maela, Bourdais, Anne, Nicolle, Ophélie, Michaux, Grégoire, Bidaud-Meynard, Aurélien

    المساهمون: Institut de Génétique et Développement de Rennes (IGDR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

    المصدر: https://hal.science/hal-04271854Test ; 2023.

    مصطلحات موضوعية: EGF Epidermal Growth Factor, polarised sorting, AP-1B, intestine, proliferation, differentiation AP-1B, Adaptor protein-subunit µ2/µ1B, EGF, Epidermal Growth Factor, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], [SDV.BC.BC]Life Sciences [q-bio]/Cellular Biology/Subcellular Processes [q-bio.SC]

    العلاقة: hal-04271854; https://hal.science/hal-04271854Test; https://hal.science/hal-04271854/documentTest; https://hal.science/hal-04271854/file/2023.05.12.540539v1.full%281%29.pdfTest; BIORXIV: 2023.05.12.540539

    الإتاحة: https://hal.science/hal-04271854Test
    https://hal.science/hal-04271854/documentTest
    https://hal.science/hal-04271854/file/2023.05.12.540539v1.full%281%29.pdfTest

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  8. 8
    دورية أكاديمية
    FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias

    المؤلفون: Shi, Ming-Jun, Fontugne, Jacqueline, Moreno-Vega, Aura, Meng, Xiang-Yu, Groeneveld, Clarice, Dufour, Florent, Kamoun, Aurélie, Viborg Lindskrog, Sia, Cabel, Luc, Krucker, Clémentine, Rapinat, Audrey, Dunois-Larde, Claire, Lepage, May-Linda, Chapeaublanc, Elodie, Levrel, Olivier, Dixon, Victoria, Lebret, Thierry, Almeida, Anna, de Reynies, Aurélien, Rochel, Natacha, Dyrskjøt, Lars, Allory, Yves, Radvanyi, François, Bernard-Pierrot, Isabelle

    المساهمون: Biologie Cellulaire et Cancer, Institut Curie Paris -Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Université Paris-Saclay, Institut Curie Paris, Hôpital Foch Suresnes, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: ISSN: 0302-2838.

    مصطلحات موضوعية: Bladder cancer, Fibroblast growth factor receptor 3, Androgen receptor, Estrogen receptor, Sex bias, Mouse model, Luminal tumors, Tyrosine kinase receptor, [SDV.CAN]Life Sciences [q-bio]/Cancer, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], [SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology

    العلاقة: hal-04274196; https://hal.science/hal-04274196Test; https://hal.science/hal-04274196/documentTest; https://hal.science/hal-04274196/file/EurUrol2023.pdfTest

    الإتاحة: https://doi.org/10.1016/j.eururo.2022.09.030Test
    https://hal.science/hal-04274196Test
    https://hal.science/hal-04274196/documentTest
    https://hal.science/hal-04274196/file/EurUrol2023.pdfTest

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  9. 9
    دورية أكاديمية
    Identification of Paired-related Homeobox Protein 1 as a key mesenchymal transcription factor in pulmonary fibrosis

    المؤلفون: Marchal-Duval, Emmeline, Homps-Legrand, Méline, Froidure, Antoine, Jaillet, Madeleine, Ghanem, Mada, Lou, Deneuville, Justet, Aurélien, Maurac, Arnaud, Vadel, Aurelie, Fortas, Emilie, Cazes, Aurelie, Joannes, Audrey, Giersh, Laura, Mal, Herve, Mordant, Pierre, Piolot, Tristan, Truchin, Marin, Mounier, Carine, Schirduan, Ksenija, Korfei, Martina, Gunther, Andreas, Mari, Bernard, Jaschinski, Frank, Crestani, Bruno, Mailleux, Arnaud

    المساهمون: Physiopathologie et Epidémiologie des Maladies Respiratoires (PHERE (UMR_S_1152 / U1152)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), AP-HP - Hôpital Bichat - Claude Bernard Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique EHESP (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Centre interdisciplinaire de recherche en biologie (CIRB), Labex MemoLife, École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Collège de France (CdF (institution))-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris Sciences et Lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA), Equipe de recherche sur les relations matrice extracellulaire-cellules (ERRMECe), Fédération INSTITUT DES MATÉRIAUX DE CERGY-PONTOISE (I-MAT), CY Cergy Paris Université (CY)-CY Cergy Paris Université (CY), Justus-Liebig-Universität Gießen = Justus Liebig University (JLU)

    المصدر: EISSN: 2050-084X ; eLife ; https://univ-rennes.hal.science/hal-04164616Test ; eLife, 2023, 12, pp.e79840. ⟨10.7554/eLife.79840⟩

    مصطلحات موضوعية: TGF beta pathway, cell biology, fibroblasts, fibrosis, human, lung, mouse, transcription factors, MESH: Mice, MESH: Animals, MESH: Humans, MESH: Transcription Factors, MESH: Cell Proliferation, MESH: Idiopathic Pulmonary Fibrosis, MESH: Transforming Growth Factor beta, MESH: Homeodomain Proteins, MESH: Protein Phosphatase 2C, [SDV.BC]Life Sciences [q-bio]/Cellular Biology

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37261432; hal-04164616; https://univ-rennes.hal.science/hal-04164616Test; https://univ-rennes.hal.science/hal-04164616/documentTest; https://univ-rennes.hal.science/hal-04164616/file/Marchal-Duval%20et%20al_elife-79840-v2.pdfTest; PUBMED: 37261432; PUBMEDCENTRAL: PMC10275639

    الإتاحة: https://doi.org/10.7554/eLife.79840Test
    https://univ-rennes.hal.science/hal-04164616Test
    https://univ-rennes.hal.science/hal-04164616/documentTest
    https://univ-rennes.hal.science/hal-04164616/file/Marchal-Duval%20et%20al_elife-79840-v2.pdfTest

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  10. 10
    دورية أكاديمية
    TGFβ inhibition and mesenchymal to epithelial transition initiation by Xenopus egg extract: first steps towards early reprogramming in fish somatic cell

    المؤلفون: Chenais, Nathalie, Le Cam, Aurélie, Guillet, Brigitte, Lareyre, Jean-Jacques, Labbé, Catherine

    المساهمون: Laboratoire de Physiologie et Génomique des Poissons = Fish Physiology and Genomics Institute (LPGP), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université de Rennes (UR), INRAE U3E, (ANR-11-INBS-0003), Centre National de la Recherche Scientifique, CNRS, ANR-11-INBS-0003,CRB-Anim,Réseau de Centres de Ressources Biologiques pour les animaux domestiques(2011)

    المصدر: ISSN: 2045-2322.

    مصطلحات موضوعية: Animals, Cell Differentiation, Cells, Cultured, Cellular Reprogramming, Epithelial-Mesenchymal Transition, Mammals, Transforming Growth Factor beta, Xenopus laevis, animal, cell culture, epithelial mesenchymal transition, genetics, mammal, metabolism, nuclear reprogramming, [SDE]Environmental Sciences

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37339990; hal-04283845; https://hal.science/hal-04283845Test; https://hal.science/hal-04283845/documentTest; https://hal.science/hal-04283845/file/s41598-023-36354-3.pdfTest; PUBMED: 37339990; WOS: 001063223800011

    الإتاحة: https://doi.org/10.1038/s41598-023-36354-3Test
    https://hal.science/hal-04283845Test
    https://hal.science/hal-04283845/documentTest
    https://hal.science/hal-04283845/file/s41598-023-36354-3.pdfTest

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