المؤلفون: Rosain, Jérémie, Neehus, Anna-Lena, Manry, Jérémy, Yang, Rui, Le Pen, Jérémie, Daher, Wassim, Liu, Zhiyong, Chan, Yi-Hao, Tahuil, Natalia, Türel, Özden, Bourgey, Mathieu, Ogishi, Masato, Doisne, Jean-Marc, Izquierdo, Helena, M, Shirasaki, Takayoshi, Le Voyer, Tom, Guérin, Antoine, Bastard, Paul, Moncada-Vélez, Marcela, Han, Ji, Eun, Khan, Taushif, Rapaport, Franck, Hong, Seon-Hui, Cheung, Andrew, Haake, Kathrin, Mindt, Barbara, C, Pérez, Laura, Philippot, Quentin, Lee, Danyel, Zhang, Peng, Rinchai, Darawan, Al Ali, Fatima, Ahmad Ata, Manar, Mahmoud, Rahman, Mahbuba, Peel, Jessica, N, Heissel, Søren, Molina, Henrik, Kendir-Demirkol, Yasemin, Bailey, Rasheed, Zhao, Shuxiang, Bohlen, Jonathan, Mancini, Mathieu, Seeleuthner, Yoann, Roelens, Marie, Lorenzo, Lazaro, Soudée, Camille, Paz, María, Elvira Josefina, González, María, Laura, Jeljeli, Mohamed, Soulier, Jean, Romana, Serge, L’honneur, Anne-Sophie, Materna, Marie, Martínez-Barricarte, Rubén, Pochon, Mathieu, Oleaga-Quintas, Carmen, Michev, Alexandre, Migaud, Mélanie, Lévy, Romain, Alyanakian, Marie-Alexandra, Rozenberg, Flore, Croft, Carys, A, Vogt, Guillaume, Emile, Jean-François, Kremer, Laurent, Ma, Cindy, S, Fritz, Jörg, H, Lemon, Stanley, M, Spaan, András, N, Manel, Nicolas, Abel, Laurent, Macdonald, Margaret, R, Boisson-Dupuis, Stéphanie, Marr, Nico, Tangye, Stuart, G, Di Santo, James, P, Zhang, Qian, Zhang, Shen-Ying, Rice, Charles, M, Béziat, Vivien, Lachmann, Nico, Langlais, David, Casanova, Jean-Laurent, Gros, Philippe, Bustamante, Jacinta

المساهمون: Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Medizinische Hochschule Hannover = Hannover Medical School (MHH), St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller University New York, Institut de Recherche en Infectiologie de Montpellier (IRIM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Yong Loo Lin School of Medicine Singapore, Hospital del Niño Jesus, San Miguel de Tucumán, Bezmiâlem Vakıf Üniversitesi, McGill University = Université McGill Montréal, Canada, Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Institut Curie Paris, University of North Carolina System (UNC), Garvan Institute of medical research, The University of Sydney, Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Universidad de Antioquia = University of Antioquia Medellín, Colombia, East China Normal University Shangaï (ECNU), Sidra Medicine Doha, Qatar, “Juan Pedro Garrahan” National Hospital of Pediatrics, Buenos Aires, Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Hôpital Cochin AP-HP, Hopital Saint-Louis AP-HP (AP-HP), Vanderbilt University Medical Center Nashville, Vanderbilt University Nashville, Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP), Hôpital Ambroise Paré AP-HP, Université de Montpellier (UM), Howard Hughes Medical Institute (HHMI), The Laboratory of Human Genetics of Infectious Diseases is supported in part by grants from Inserm, Paris Cité University, the St. Giles Foundation, The Rockefeller University, the Center for Clinical and Translational Science (UL1TR001866), the National Center for Research Resources and the National Center for Advancing Sciences, the National Institutes of Health (NIH), (R01AI095983, R01AI088364, R01AI163029, and U19AI162568), the National Institute of Allergy and Infectious Diseases, the French National Research Agency (ANR) under the “Investments for the future” program (ANR-10-IAHU-01), the Integrative Biology of Emerging Infectious Diseases Laboratory of Excellence (ANR-10-LABX-62-IBEID), the French Foundation for Medical Research (FRM) (EQU201903007798), the ANRS Nord-Sud (ANRS-COV05), ANRS (ECTZ170784-ANRS0073), GENVIR (ANR-20-CE93-003), GENMSMD (ANR-16-CE17-0005-01), AABIFNCOV (ANR-20-CO11-0001), GenMIS-C (ANR-21-COVR-0039), SUNLIVE (ANR-19-CE15-0012-01), MAFMACRO (ANR-22-CE92-0008) grants, Ecos-NORD (ECOS N°C19S01), the Fisher Center for Alzheimer's Research Foundation, the Meyer Foundation, the JPB Foundation, the European Union’s Horizon 2020 research and innovation program (824110, EASI-Genomics), the Square Foundation, Grandir–Fonds de solidarité pour l’Enfance, the Fondation du Souffle, the SCOR Corporate Foundation for Science, the French Ministry of Higher Education, Research, and Innovation (MESRI-COVID-19), and REACTing-INSERM. The Laboratory of Virology and Infectious Disease was supported in part by the NIH (R01AI091707-10 to C.M.R.). J.L.P. was supported by the Francois Wallace Monahan Postdoctoral Fellowship at The Rockefeller University and the European Molecular Biology Organization Long-Term Fellowship (ALTF 380-2018). N. Marr was supported by Sidra Medicine and the Qatar National Research Fund (NPRP9-251-3-045). The Yale Center for Mendelian Genomics (UM1HG006504) was funded by the National Human Genome Research Institute, the Yale GSP Coordinating Center (U24 HG008956), and the Yale High-Performance Computing Center (S10OD018521). This research was partly supported by Calcul Québec, Compute Canada Canadian Institutes of Health Research (CIHR) Project Grant to D. Langlais. (#168959) and a CIHR Foundation Grant (to P.G.). D. Langlais was also supported by an FRQS Chercheur-Boursier Junior 1 Award and the Calgary Foundation for Innovation John R. Evans Leaders Fund. P.G. is supported by a Distinguished James McGill Professorship award from McGill University. S.M.L is supported by the NIH: R01-AI103083 and R01-AI150095. J.R. was supported by poste d’accueil Inserm”. J.R., P.B., and T.L.V were supported by the MD-PhD program of the Imagine Institute by the Bettencourt Schueller Foundation. N.L received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (852178 grant), German Research Foundation,(DFG) under Germany’s Excellence Strategy—EXC 2155—project number 390874280 and REBIRTH “Förderung aus Mitteln des Niedersächsischen Vorab”. A.-L.N. was supported by the international PhD program of the Imagine Institute, by the Bettencourt Schueller Foundation and the fin de thèse FRM program (FDT202204015102). R.Y. was supported by the Sackler Center for Biomedicine and Nutrition, the Shapiro-Silverberg Fund for the Advancement of Translational Research at the Center for Clinical and Translational Science of the Rockefeller University, and the Research Grant Program from the Immune Deficiency Foundation. D. Lee. was supported by FRMfellowship (FDM202006011282). C.S.M was supported by an Early-Mid Career Research Fellowship from the Department of Health of the New South Wales Government of Australia. S.G.T was supported by an NHMRC Leadership 3 Investigator Grant (1176665) and NHMRC grant (1113904). M.O. was supported by the David Rockefeller Graduate Program, the Funai Foundation for Information Technology, the Honjo International Scholarship Foundation, and the New York Hideyo Noguchi Memorial Society. This work was supported by grants from ANRS (ECTZ118797), Sidaction (20-2-AEQ-12822-2), and FRM (EQU202103012774) to N. Manel, and H.I. was supported by fellowships from Institut Curie, Seneca Foundation (20941/PD/18), and ANRS (ECTZ171453). A.N.S. was supported in part by the European Union’s Horizon 2020 research and innovation program (789645 Marie Sklodowska-Curie grant). Y.-H.C. is supported by an A∗STAR International Fellowship. J. Bohlen is an EMBO postdoctoral fellow. We thank the NIH Tetramer Core Facility (NTCF) for providing the 5-OP-RU-loaded MR1 tetramer, which was developed jointly with Dr. James McCluskey, Dr. Jamie Rossjohn, and Dr. David Fairlie., ANR-10-IAHU-0001,Imagine,Institut Hospitalo-Universitaire Imagine(2010), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-16-CE17-0005,GENMSMD,Dissection génétique de la Susceptibilité Mendélienne aux infections mycobactériennes chez l'homme(2016), ANR-20-CO11-0001,AABIFNCOV,Bases génétiques et immunologiques des auto-anticorps contre les interférons de type I prédisposant aux formes sévères de COVID-19.(2020), ANR-21-COVR-0039,GenMIS-C,Recherche des Déficits immunitaires innées monogéniques prédisposant au syndrome inflammatoire multisystémique chez l'enfant.(2021), ANR-19-CE15-0012,SUNLIVE,Variabilité structurale et fonctionnelle des lipides complexes chez les mycobactéries : de l'assemblage de la paroi à la physiopathologie et virulence(2019), ANR-22-CE92-0008,MAFMACRO,Genetic predisposition and the role of myeloid cells in the susceptibility to mycobacterial infection(2022), European Project: 824110,H2020-INFRAIA-2018-1,EASI-Genomics(2019)

المصدر: ISSN: 0092-8674.

مصطلحات موضوعية: inborn errors of immunity, Mycobacterium, interferon-γ, interferon-stimulated gene, IRF1, viruses, macrophages, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36736301; info:eu-repo/grantAgreement//824110/EU/European Advanced infraStructure for Innovative Genomics/EASI-Genomics; pasteur-04130575; https://pasteur.hal.science/pasteur-04130575Test; https://pasteur.hal.science/pasteur-04130575/documentTest; https://pasteur.hal.science/pasteur-04130575/file/1-s2.0-S0092867422015811-main.pdfTest; PUBMED: 36736301; PUBMEDCENTRAL: PMC9907019

الإتاحة: https://doi.org/10.1016/j.cell.2022.12.038Test
https://pasteur.hal.science/pasteur-04130575Test
https://pasteur.hal.science/pasteur-04130575/documentTest
https://pasteur.hal.science/pasteur-04130575/file/1-s2.0-S0092867422015811-main.pdfTest

المؤلفون: Lorin, Valerie, Fernández, Ignacio, Masse-Ranson, Guillemette, Bouvin-Pley, Mélanie, Molinos-Albert, Luis, M., Planchais, Cyril, Hieu, Thierry, Péhau-Arnaudet, Gérard, Hrebík, Dominik, Girelli-Zubani, Giulia, Fiquet, Oriane, Guivel-Benhassine, Florence, Sanders, Rogier, W., Walker, Bruce, D., Schwartz, Olivier, Scheid, Johannes, F., Dimitrov, Jordan, D., Plevka, Pavel, Braibant, Martine, Seaman, Michael, S., Bontems, François, Di Santo, James, P., Rey, Félix, A., Mouquet, Hugo

المساهمون: Immunologie humorale - Humoral Immunology, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Virologie Structurale, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Morphogénèse et antigénicité du VIH, des Virus des Hépatites et Emergents (MAVIVHe), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Imagopole (CITECH), Institut Pasteur Paris (IP), Microscopie Ultrastructurale (Plate-forme), Masaryk University Brno (MUNI), Virus et Immunité - Virus and immunity (CNRS-UMR3569), University of Amsterdam Amsterdam = Universiteit van Amsterdam (UvA), Weill Medical College of Cornell University New York, Massachusetts General Hospital Boston, Harvard Medical School Boston (HMS), Rockefeller University New York, Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Beth Israel Deaconess Medical Center Boston (BIDMC), Institut de Chimie des Substances Naturelles (ICSN), Institut de Chimie - CNRS Chimie (INC-CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), The NanoImaging Core was created with the help of a grant from the French Government’s Investissements d’Avenir program (EQUIPEX CACSICE - Centre d’analyse de systèmes complexes dans les environnements complexes, ANR-11-EQPX-0008). We thank the NIH AIDS Reagent Program (Division of AIDS, National Institute of Allergy and Infectious Diseases, NIH) for contributing to reagents and the Agence National de Recherche sur le SIDA et les hépatites virales (ANRS) for an equipment grant support. The Biomics platform is supported by France Génomique (ANR-10-INBS-09-09) and IBISA. I. Fernández and C. Planchais were recipients of an ANRS postdoctoral fellowship. The J.P. Di Santo laboratory received support from the Vaccine Research Institute (Créteil, France). H. Mouquet received core grants from the Institut Pasteur, Institut national de la santé et de la recherche médicale, and the Milieu Intérieur Program (ANR-10-LABX-69-01). This work was supported by the European Research Council Seventh Framework Program (ERC-2013-StG 337146), and by Gilead Sciences HIV Cure Grants (#00397)., ANR-11-EQPX-0008,CACSICE,Centre d'analyse de systèmes complexes dans les environnements complexes(2011), ANR-10-INBS-0009,France Génomique,Organisation et montée en puissance d'une Infrastructure Nationale de Génomique(2010), ANR-10-LABX-0069,MILIEU INTERIEUR,GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE(2010), European Project: 337146,EC:FP7:ERC,ERC-2013-StG,HUMANTIVIRUSES(2014)

المصدر: ISSN: 0022-1007.

مصطلحات موضوعية: [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35230385; info:eu-repo/grantAgreement/EC/FP7/337146/EU/Human Antibody Responses to Viruses/HUMANTIVIRUSES; pasteur-03654254; https://pasteur.hal.science/pasteur-03654254Test; https://pasteur.hal.science/pasteur-03654254/documentTest; https://pasteur.hal.science/pasteur-03654254/file/jem_20212045.pdfTest; PUBMED: 35230385; PUBMEDCENTRAL: PMC8932546

الإتاحة: https://doi.org/10.1084/jem.20212045Test
https://pasteur.hal.science/pasteur-03654254Test
https://pasteur.hal.science/pasteur-03654254/documentTest
https://pasteur.hal.science/pasteur-03654254/file/jem_20212045.pdfTest

المؤلفون: Gransagne, Marion, Aymé, Gabriel, Brier, Sébastien, Chauveau-Le Friec, Gaëlle, Meriaux, Véronique, Nowakowski, Mireille, Déjardin, François, Levallois, Sylvain, Dias de Melo, Guilherme, Donati, Flora, Prot, Matthieu, Brûlé, Sébastien, Raynal, Bertrand, Bellalou, Jacques, Goncalves, Pedro, Montagutelli, Xavier, Di Santo, James, P, Lazarini, Françoise, England, Patrick, Petres, Stéphane, Escriou, Nicolas, Lafaye, Pierre

المساهمون: Département de Santé Globale - Department Global Health, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Ingénierie des Anticorps (plate-forme) - Antibody Engineering (Platform), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Plateforme Technologique de RMN Biologique et HDX-MS - Biological NMR and HDX-MS Technological Platform, Plateforme technologique Production et purification de protéines recombinantes – Production and Purification of Recombinant Proteins Technological Platform (PPR), Biologie des Infections - Biology of Infection, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Lyssavirus, épidémiologie et neuropathologie - Lyssavirus Epidemiology and Neuropathology, Génétique Moléculaire des Virus à ARN - Molecular Genetics of RNA Viruses (GMV-ARN (UMR_3569 / U-Pasteur_2)), Centre National de Référence des virus des infections respiratoires (dont la grippe) - National Reference Center Virus Influenzae Paris (CNR - laboratoire coordonnateur), Génomique évolutive des virus à ARN - Evolutionary genomics of RNA viruses, Biophysique Moléculaire (plateforme) - Molecular Biophysics (platform), Immunité Innée - Innate Immunity, Génétique de la souris - Mouse Genetics, Perception et Mémoire / Perception and Memory, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), P. G. and J. P. D. received support from the ANR grant “COVARIMM.”We want to thank Nicolas Wolff and Baptiste Colcombet-Cazenave for their technical help for the production of the different VHHs. The strain BetaCoV/France/IDF0372/2020 was supplied by the National Reference Centre for Respiratory Viruses hosted by Institut Pasteur (Paris, France) and headed by Pr. Sylvie van der Werf. The human sample from which strain BetaCoV/France/IDF0372/2020 was isolated was provided by Dr X. Lescure and Pr. Y. Yazdanpanah from the Bichat Hospital, Paris, France. Moreover, the strain BetaCoV/France/IDF0372/2020 was supplied through the European Virus Archive goes Global (Evag) platform, a project that has received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No 653316. We are grateful to the National Reference Center for Respiratory Viruses for providing the variants of concern used in mouse experiments, to Sylvie van der Werf and Etienne Simon-Lorière for support and scientific advice, and to Grégory Jouvion for histological evaluation. We thank the Institut Pasteur Histology platform for histological slides preparation. Mouse experiments on variants of concern were supported by ANR grants HUMOCID (ANR-20-COVI-0028-01) and IBEID (ANR-10-LABX-62-IBEID) and by the EU Horizon 2020 RECOVER project (No. 101003589). The authors would like to thank the DIM 1HEALTH région Ile-de-France scheme for funding the Centrifection project that allowed to purchase the Optima ultracentrifuge. The CACSICE Equipex ANR-11-EQPX-0008 is acknowledged., ANR-20-COVI-0053,CoVarImm,Variation de la réponse immune systémique et muqueuse pendant l'infection par le SRAS-CoV-2 et la convalescence(2020), ANR-20-COVI-0028,HuMoCID,Développement de modèles murins de COVID-19(2020), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-11-EQPX-0008,CACSICE,Centre d'analyse de systèmes complexes dans les environnements complexes(2011), European Project: 653316,H2020,H2020-INFRAIA-2014-2015,EVAg(2015)

المصدر: ISSN: 0021-9258.

مصطلحات موضوعية: COVID-19, antibody engineering, diagnostic, hydrogen-deuterium exchange, immunochemistry, nanobodies, nucleoprotein, phage display, single domain antibodies, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34678315; info:eu-repo/grantAgreement//653316/EU/European Virus Archive goes global/EVAg; pasteur-03524979; https://pasteur.hal.science/pasteur-03524979Test; https://pasteur.hal.science/pasteur-03524979/documentTest; https://pasteur.hal.science/pasteur-03524979/file/VHH%20anti%20SARS-CoV2%20nucleoprotein%20Lafaye%20JBC%20%281%29.pdfTest; PUBMED: 34678315; PUBMEDCENTRAL: PMC8526496

الإتاحة: https://doi.org/10.1016/j.jbc.2021.101290Test
https://pasteur.hal.science/pasteur-03524979Test
https://pasteur.hal.science/pasteur-03524979/documentTest
https://pasteur.hal.science/pasteur-03524979/file/VHH%20anti%20SARS-CoV2%20nucleoprotein%20Lafaye%20JBC%20%281%29.pdfTest

المؤلفون: Croft, Carys, A, Thaller, Anna, Marie, Solenne, Doisne, Jean-Marc, Surace, Laura, Yang, Rui, Puel, Anne, Bustamante, Jacinta, Casanova, Jean-Laurent, Di Santo, James, P.

المساهمون: Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Rockefeller University New York, Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Howard Hughes Medical Institute (HHMI), Funding was provided by Institut Pasteur, the Institut National de la Santé et de la Recherche Médicale (Inserm), the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (695467 – ILC_REACTIVITY), the National Institute of Allergy and Infectious Diseases, NIH (R01AI095983) and the French National Research Agency (ANR) GENMSMD (ANR-16-CE17-0005-01) to J.P.D. C.A.C. is enrolled in the Pasteur-Paris University (PPU) International PhD Program that receives funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement #665807, from the Labex Revive (10-LABX-0073), Institut Pasteur and the Fondation ARC. A.T. received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement #765104., We are indebted to the patients and their families for their essential collaboration. We thank members on Innate Immunity Unit for the helpful discussions, and the Center for Translational Science (CRT)- Cytometry and Biomarkers Unit of Technology and Service (CB UTechS) at Institut Pasteur for their technical support., ANR-16-CE17-0005,GENMSMD,Dissection génétique de la Susceptibilité Mendélienne aux infections mycobactériennes chez l'homme(2016), ANR-10-LABX-0073,REVIVE,Stem Cells in Regenerative Biology and Medicine(2010), European Project: 695467,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ILC_REACTIVITY(2016)

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: MESH: Cell Differentiation, MESH: Humans, MESH: Immunity, Innate, MESH: Interleukin-23, MESH: Killer Cells, Natural, MESH: Lymphocytes, MESH: Lymphoid Progenitor Cells, MESH: Nuclear Receptor Subfamily 1, Group F, Member 3, MESH: Receptors, Notch, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35896601; info:eu-repo/grantAgreement//695467/EU/Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease/ILC_REACTIVITY; pasteur-04130561; https://pasteur.hal.science/pasteur-04130561Test; https://pasteur.hal.science/pasteur-04130561/documentTest; https://pasteur.hal.science/pasteur-04130561/file/s41467-022-32089-3.pdfTest; PUBMED: 35896601; PUBMEDCENTRAL: PMC9329340

الإتاحة: https://doi.org/10.1038/s41467-022-32089-3Test
https://pasteur.hal.science/pasteur-04130561Test
https://pasteur.hal.science/pasteur-04130561/documentTest
https://pasteur.hal.science/pasteur-04130561/file/s41467-022-32089-3.pdfTest

المؤلفون: de Cevins, Camille, Luka, Marine, Smith, Nikaïa, Meynier, Sonia, Magérus, Aude, Carbone, Francesco, García-Paredes, Víctor, Barnabei, Laura, Batignes, Maxime, Boullé, Alexandre, Stolzenberg, Marie-Claude, Pérot, Brieuc, P., Charbit, Bruno, Fali, Tinhinane, Pirabakaran, Vithura, Sorin, Boris, Riller, Quentin, Abdessalem, Ghaith, Beretta, Maxime, Grzelak, Ludivine, Goncalves, Pedro, Di Santo, James, P., Mouquet, Hugo, Schwartz, Olivier, Zarhrate, Mohammed, Parisot, Mélanie, Bole-Feysot, Christine, Masson, Cécile, Cagnard, Nicolas, Corneau, Aurélien, Brunaud, Camille, Zhang, Shen-Ying, Casanova, Jean-Laurent, Bader-Meunier, Brigitte, Haroche, Julien, Melki, Isabelle, Lorrot, Mathie, Oualha, Mehdi, Moulin, Florence, Bonnet, Damien, Belhadjer, Zahra, Leruez, Marianne, Allali, Slimane, Gras-Leguen, Christèle, de Pontual, Loïc, Study Group, Pediatric-Biocovid, Fischer, Alain, Duffy, Darragh, Rieux-Laucat, Fredéric, Toubiana, Julie, Ménager, Mickaël

المساهمون: Inflammatory Responses and Transcriptomic Networks in diseases (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Sanofi Aventis R&D Chilly-Mazarin, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Immunologie Translationnelle - Translational Immunology lab, Institut Pasteur Paris (IP), Immunogenetics of pediatric autoimmune diseases (Equipe Inserm U1163), Cytometrie et Biomarqueurs – Cytometry and Biomarkers (UTechS CB), Immunologie humorale - Humoral Immunology, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Virus et Immunité - Virus and immunity (CNRS-UMR3569), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Immunité Innée - Innate Immunity, Structure Fédérative de Recherche Necker (UAR 3633 / US24), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Cytométrie Pitié-Salpêtrière (PASS-CYPS), Unité Mixte de Service Production et Analyse de données en Sciences de la vie et en Santé (PASS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Human genetics of infectious diseases : Mendelian predisposition (Equipe Inserm U1163), Rockefeller University New York, Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre d'Immunologie et des Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), CHU Pitié-Salpêtrière AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), AP-HP Hôpital universitaire Robert-Debré Paris, Université Paris Cité (UPCité), CHU Trousseau APHP, Centre d’Investigation Clinique de Nantes (CIC Nantes), Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Hôpital Jean Verdier AP-HP, Université Paris 13 (UP13), Collège de France (CdF (institution)), Biodiversité et Epidémiologie des Bactéries pathogènes - Biodiversity and Epidemiology of Bacterial Pathogens, ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018), ANR-17-EURE-0013,GENE,Génétique et Epigénétique Nouvelle Ecole(2017), ANR-18-RHUS-0010,ATRACTION,Autoimmunity/inflammation Through Rnaseq Analysis at the single Cell level for Therapeutic Innovation(2018)

المصدر: ISSN: 2666-6340 ; Med ; https://hal.sorbonne-universite.fr/hal-03590894Test ; Med, 2021, 2 (9), pp.1072-1092.e7. ⟨10.1016/j.medj.2021.08.002⟩.

مصطلحات موضوعية: COVID-19, SARS-CoV-2, scRNA-seq, MIS-C, PIMS-TS, Kawasaki Disease, myocarditis, TNF-α and NF-κB signaling, lack of responses to type I and type II IFN secretion, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34414385; hal-03590894; https://hal.sorbonne-universite.fr/hal-03590894Test; https://hal.sorbonne-universite.fr/hal-03590894/documentTest; https://hal.sorbonne-universite.fr/hal-03590894/file/S2666634021002877.pdfTest; PII: S2666-6340(21)00287-7; PUBMED: 34414385; PUBMEDCENTRAL: PMC8363470

الإتاحة: https://doi.org/10.1016/j.medj.2021.08.002Test
https://hal.sorbonne-universite.fr/hal-03590894Test
https://hal.sorbonne-universite.fr/hal-03590894/documentTest
https://hal.sorbonne-universite.fr/hal-03590894/file/S2666634021002877.pdfTest

المؤلفون: Smith, Nikaïa, Goncalves, Pedro, Charbit, Bruno, Grzelak, Ludivine, Beretta, Maxime, Planchais, Cyril, Bruel, Timothée, Rouilly, Vincent, Bondet, Vincent, Hadjadj, Jérôme, Yatim, Nader, Pere, Helene, Merkling, Sarah, H., Ghozlane, Amine, Kernéis, Solen, Rieux-Laucat, Frederic, Terrier, Benjamin, Schwartz, Olivier, Mouquet, Hugo, Duffy, Darragh, Di Santo, James, P.

المساهمون: Immunologie Translationnelle - Translational Immunology lab, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Cytometrie et Biomarqueurs – Cytometry and Biomarkers (UTechS CB), Virus et Immunité - Virus and immunity (CNRS-UMR3569), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Paris Cité (UPCité), Immunologie humorale - Humoral Immunology, Datactix, Service de médecine interne et centre de référence des maladies rares CHU Cochin, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Immunogenetics of pediatric autoimmune diseases (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Interactions Virus-Insectes - Insect-Virus Interactions (IVI), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Hôpital Cochin AP-HP, Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Epidémiologie et modélisation de la résistance aux antimicrobiens - Epidemiology and modelling of bacterial escape to antimicrobials (EMAE), Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), This study was supported by grants from the Institut Pasteur (CoVarImm) and from the Agence National de la Recherche (ANR-flash COVID-19, to D.D. and J.P.D.), and by the Laboratoire d’Excellence ‘Milieu Intérieur’ (grant no. ANR-10-LABX-69-01) and the Fonds IMMUNOV, for Innovation in Immunopathology. N.S. is a recipient of the Pasteur-Roux-Cantarini Fellowship., We thank the UTechS CB of the Center for Translational Research, Institut Pasteur for supporting Luminex and Simoa analysis. We thank L. Motreff and L. Ma (Biomics Platform supported by France Génomique, ANR-10-INBS-09-09), IBISA and the Illumina COVID-19 Projects’ offer for microbial sequencing. We thank the Bioinformatics and Biostatistics HUB, Institut Pasteur for the assistance with the 16S rRNA-sequencing data analysis. We acknowledge all health-care workers involved in the diagnosis and treatment of patients in Cochin Hospital, especially C. Azoulay, L. Beaudeau, E. Canoui, P. Cohen, A. Contejean, B. Dunogué, D. Journois, P. Legendre, J. Marey and A. Régent., ANR-20-COVI-0053,CoVarImm,Variation de la réponse immune systémique et muqueuse pendant l'infection par le SRAS-CoV-2 et la convalescence(2020), ANR-10-LABX-0069,MILIEU INTERIEUR,GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE(2010)

المصدر: ISSN: 1529-2908.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34471264; pasteur-03384279; https://pasteur.hal.science/pasteur-03384279Test; https://pasteur.hal.science/pasteur-03384279/documentTest; https://pasteur.hal.science/pasteur-03384279/file/Distinct_systemic_and_mucosal_immune_responses_dur.pdfTest; PUBMED: 34471264

الإتاحة: https://doi.org/10.1038/s41590-021-01028-7Test
https://pasteur.hal.science/pasteur-03384279Test
https://pasteur.hal.science/pasteur-03384279/documentTest
https://pasteur.hal.science/pasteur-03384279/file/Distinct_systemic_and_mucosal_immune_responses_dur.pdfTest

المؤلفون: Monel, Blandine, Planas, Delphine, Grzelak, Ludivine, Smith, Nikaïa, Robillard, Nicolas, Staropoli, Isabelle, Goncalves, Pedro, Porrot, Françoise, Guivel-Benhassine, Florence, Guinet, Nathalie Demory, Rodary, Julien, Puech, Julien, Euzen, Victor, Bélec, Laurent, Orvoen, Galdric, Nunes, Léa, Moulin, Véronique, Fourgeaud, Jacques, Wack, Maxime, Imbeaud, Sandrine, Campagne, Pascal, Duffy, Darragh, Di Santo, James, P., Bruel, Timothée, Péré, Hélène, Veyer, David, Schwartz, Olivier

المساهمون: Virus et Immunité - Virus and immunity (CNRS-UMR3569), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Vaccine Research Institute Créteil, France (VRI), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université Paris Cité (UPCité), Immunologie Translationnelle - Translational Immunology lab, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Hôpital Européen Georges Pompidou APHP (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Hôpital Vaugirard-Gabriel Pallez, Hôpital Corentin Celton Issy-les-Moulineaux, Laboratoire de Virologie CHU Necker, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Necker - Enfants Malades AP-HP, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Work in OS lab is funded by Institut Pasteur, Urgence COVID-19 Fundraising Campaign of Institut Pasteur, ANRS, the Vaccine Research Institute (ANR-10-LABX-77), Labex IBEID (ANR-10-LABX-62-IBEID), ANR/FRM Flash Covid PROTEO-SARS-CoV-2 and IDISCOVR, Fondation pour la Recherche Médicale. DP is supported by the Vaccine Research Institute. LG is supported by the French Ministry of Higher Education, Research and Innovation. DD and JDS are funded by the ANR-20-COVI-0053 grant., We thank Maaran Michael Rajah, Nicoletta Casartelli, Michael White and Jeremy Dufloo for discussion and critical reading of the manuscript. We thank AGEPS, Assistance Publique - Hôpitaux de Paris, for providing the RDTs. We thank the patients who participated in the study, the clinical staff involved in their management, Théo Hirsch for stimulating discussions. We thank members of the Virus and Immunity Unit for discussion and help, Nathalie Aulner and the UtechS Photonic BioImaging (UPBI) core facility (Institut Pasteur), a member of the France BioImaging network, for image acquisition and analysis, and Cyril Planchais & Hugo Mouquet for the kind gift of mAb48., ANR-10-LABX-0077,VRI,Initiative for the creation of a Vaccine Research Institute(2010), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-20-COVI-0059,PROTEO-SARS-CoV-2,Protéomique du SARS-CoV-2(2020), ANR-20-COVI-0053,CoVarImm,Variation de la réponse immune systémique et muqueuse pendant l'infection par le SRAS-CoV-2 et la convalescence(2020)

المصدر: ISSN: 2352-3964 ; EBioMedicine ; https://hal.sorbonne-universite.fr/hal-03408666Test ; EBioMedicine, 2021, 73, pp.103637. ⟨10.1016/j.ebiom.2021.103637⟩.

مصطلحات موضوعية: COVID-19, SARS-CoV-2, Nasal swabs, variants, infectious particles, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34678613; hal-03408666; https://hal.sorbonne-universite.fr/hal-03408666Test; https://hal.sorbonne-universite.fr/hal-03408666/documentTest; https://hal.sorbonne-universite.fr/hal-03408666/file/PIIS2352396421004308.pdfTest; PUBMED: 34678613; PUBMEDCENTRAL: PMC8526063

الإتاحة: https://doi.org/10.1016/j.ebiom.2021.103637Test
https://hal.sorbonne-universite.fr/hal-03408666Test
https://hal.sorbonne-universite.fr/hal-03408666/documentTest
https://hal.sorbonne-universite.fr/hal-03408666/file/PIIS2352396421004308.pdfTest

المؤلفون: Surace, Laura, Doisne, Jean-Marc, Croft, Carys, A, Thaller, Anna, Escoll, Pedro, Marie, Solenne, Petrosemoli, Natalia, Guillemot, Vincent, Dardalhon, Valerie, Topazio, Davide, Cama, Antonia, Buchrieser, Carmen, Taylor, Naomi, Amit, Ido, Musumeci, Olimpia, Di Santo, James, P

المساهمون: Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), École Doctorale Bio Sorbonne Paris Cité Paris (ED562 - BioSPC), Université Sorbonne Paris Cité (USPC)-Université Paris Cité (UPCité), Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria, Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Department of Otolaryngology, Ospedale “Giuseppe Mazzini” di Teramo, Department of Maxillofacial and Otolaryngology, Hospital "Floraspe Renzetti", Department of Immunology Rehovot, Israël, Weizmann Institute of Science Rehovot, Israël, Department of Clinical and Experimental Medicine Messina, Italy, University of Messina, The Innate Immunity Unit is supported by grants from the Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur, the Agence National pour le Recherche (ANR) and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation program (695467, ILC_REACTIVITY). A.T. is supported by European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement no. 765104. C.B.’s group was supported by the Fondation pour la Recherche Médicale (FRM) grant no. EQU201903007847 and the grant no. ANR-10-LABX-62-IBEID. L.S. was supported by an SNSF-Early PostDoc. Mobility fellowship and a Marie Curie grant (H2020- MSCA-IF-2017)., We thank all the members of the Innate Immunity Unit for helpful discussions, the Centre de Recherche Translationnelle and the logistic department of Institut Pasteur. We thank the CB-UTechS platform for cytometry support and the Imagopole-CiTech (part of France-BioImaging supported by ANR grant no. ANR-10-INSB-04-01, Conseil de la Region Ile-de-France, FRM) for technical support., The study was conceptualized by L.S. and J.P.D. Experiments were coordinated by L.S. FACS and subsequent analyses were performed by L.S., C.A.C., A.T., J.-M.D. and S.M. Confocal microscopy analysis was performed by P.E., C.B. and L.S. Bioinformatic analyses were performed by N.P. and V.G. RNA-seq experiments were conducted by I.A. O.M., V.D., N.T., D.T. and A.C. provided resources. L.S. and J.P.D. wrote the paper. Funding was acquired by L.S. and J.P.D., and the study was supervised by J.P.D., ANR-10-INBS-0004,France-BioImaging,Développment d'une infrastructure française distribuée coordonnée(2010), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), European Project: 695467,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) ,ILC_REACTIVITY(2016), European Project: 765104,MATURE-NK, European Project: 796004,BIF-SCV

المصدر: ISSN: 1529-2908.

مصطلحات موضوعية: MESH: Amino Acids, Branched-Chain, MESH: Arginine, MESH: Cytokines, MESH: Energy Metabolism, MESH: Humans, MESH: Immunity, Innate, MESH: Interleukin-33, MESH: Lymphocyte Activation, MESH: Mitochondria, MESH: Mitochondrial Diseases, MESH: Phenotype, MESH: Th2 Cells, MESH: Case-Control Studies, MESH: Cell Proliferation, MESH: Cells, Cultured, [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34686862; info:eu-repo/grantAgreement//695467/EU/Biological Determinants of ILC Reactivity for Immune Responses in Health and Disease/ILC_REACTIVITY; info:eu-repo/grantAgreement//765104/EU/MAnufacturing of TUmour-REactive Natural Killer cells/MATURE-NK; info:eu-repo/grantAgreement//796004/EU/H2020-MSCA-IF-2017 Bifurcations in several complex variables/BIF-SCV; pasteur-03499188; https://pasteur.hal.science/pasteur-03499188Test; https://pasteur.hal.science/pasteur-03499188/documentTest; https://pasteur.hal.science/pasteur-03499188/file/2021_Nat%20Immunol_Surace.pdfTest; PUBMED: 34686862; PUBMEDCENTRAL: PMC8553616

الإتاحة: https://doi.org/10.1038/s41590-021-01043-8Test
https://pasteur.hal.science/pasteur-03499188Test
https://pasteur.hal.science/pasteur-03499188/documentTest
https://pasteur.hal.science/pasteur-03499188/file/2021_Nat%20Immunol_Surace.pdfTest

المؤلفون: Vanderkerken, Matthias, Baptista, Antonio, P., de Giovanni, Marco, Fukuyama, Satoshi, Browaeys, Robin, Scott, Charlotte, L., Norris, Paula, S., Eberl, Gerard, Di Santo, James, P., Vivier, Eric, Saeys, Yvan, Hammad, Hamida, Cyster, Jason, G., Ware, Carl, F., Tumanov, Alexei, V., de Trez, Carl, Lambrecht, Bart, N.

المساهمون: VIB-UGent Center for Inflammation Research Gand, Belgique (IRC), VIB Belgium, Universiteit Gent = Ghent University (UGENT), University of California San Francisco (UC San Francisco), University of California (UC), The University of Tokyo (UTokyo), Sanford Burnham Prebys Medical Discovery Institute, Microenvironnement et Immunité - Microenvironment and Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunité Innée - Innate Immunity, Innate Pharma, Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), University of Texas Health Science Center, The University of Texas Health Science Center at Houston (UTHealth), Vrije Universiteit Brussel (VUB), Erasmus University Medical Center Rotterdam (Erasmus MC), M. Vanderkerken is supported by a fellowship from Fonds Wetenschappelijk Onderzoek Vlaanderen, A.P. Baptista is supported by a Marie-Sklodowska Curie Action fellowship as part of Horizon 2020, C.L. Scott is supported by the Fonds Wetenschappelijk Onderzoek Vlaanderen and a European Research Council starting grant, Y. Saeys is supported by the Fonds Wetenschappelijk Onderzoek Vlaanderen and the Marylou Ingram Scholar program, H. Hammad is supported by a research initiative grant from Ghent University, A.V. Tumanov is supported by grants from the National Institutes of Health (AI135574) and the Max and Minnie Tomerlin Voelcker Fund, and B.N. Lambrecht is supported by a European Research Council advanced grant, a research initiative grant from Ghent University, and an Excellence of Science research grant.

المصدر: ISSN: 0022-1007.

مصطلحات موضوعية: [SDV.IMM]Life Sciences [q-bio]/Immunology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33724364; pasteur-03258252; https://pasteur.hal.science/pasteur-03258252Test; https://pasteur.hal.science/pasteur-03258252/documentTest; https://pasteur.hal.science/pasteur-03258252/file/jem_20190835.pdfTest; PUBMED: 33724364; PUBMEDCENTRAL: PMC7970251

الإتاحة: https://doi.org/10.1084/jem.20190835Test
https://pasteur.hal.science/pasteur-03258252Test
https://pasteur.hal.science/pasteur-03258252/documentTest
https://pasteur.hal.science/pasteur-03258252/file/jem_20190835.pdfTest

المؤلفون: Amblard, Franck, Bouclé, Sébastien, Bassit, Leda, Cox, Bryan, Sari, Ozkan, Tao, Sijia, Chen, Zhe, Ozturk, Tugba, Verma, Kiran, Russell, Olivia, Rat, Virgile, de Rocquigny, Hugues, Fiquet, Oriane, Boussand, Maud, Di Santo, James, P, Strick-Marchand, Helene, Schinazi, Raymond, F

المساهمون: Emory University School of Medicine, Emory University Atlanta, GA, Morphogénèse et antigénicité du VIH, des Virus des Hépatites et Emergents (MAVIVHe), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), Immunité Innée - Innate Immunity, Institut Pasteur Paris (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported in part by NIH Grant 1-R01-AI-132833(RFS), and 5P30-AI-50409 (CFAR)(RFS), by Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS) Grants #2016-16180 and #2016-16365, European Commission Seventh Framework Programme PATHCo(HEALTH-F3-2012-305578), Institut Pasteur, and Institut national de la santé et de la recherche médicale (HSM), by ANRS and Institut national de la santé et de la recherche médicale (INSERM) (HDR)., European Project: 305578,EC:FP7:HEALTH,FP7-HEALTH-2012-INNOVATION-1,PATHCO(2012)

المصدر: ISSN: 0066-4804.

مصطلحات موضوعية: antiviral, capsid, cccDNA, hepatitis B virus, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31712213; info:eu-repo/grantAgreement/EC/FP7/305578/EU/Pathogen COinfection:HIV, Tuberculosis, Malaria and Hepatitis C virus/PATHCO; pasteur-02875583; https://pasteur.hal.science/pasteur-02875583Test; https://pasteur.hal.science/pasteur-02875583/documentTest; https://pasteur.hal.science/pasteur-02875583/file/Antimicrobial%20Agents%20and%20Chemotherapy-2019-Amblard-AAC.01701-19.full.pdfTest; PUBMED: 31712213

الإتاحة: https://doi.org/10.1128/AAC.01701-19Test
https://pasteur.hal.science/pasteur-02875583Test
https://pasteur.hal.science/pasteur-02875583/documentTest
https://pasteur.hal.science/pasteur-02875583/file/Antimicrobial%20Agents%20and%20Chemotherapy-2019-Amblard-AAC.01701-19.full.pdfTest