المؤلفون: Scekic-Zahirovic, Jelena, Sanjuan-Ruiz, Inmaculada, Kan, Vanessa, Megat, Salim, De Rossi, Pierre, Dieterlé, Stéphane, Cassel, Raphaelle, Jamet, Marguerite, Kessler, Pascal, Wiesner, Diana, Tzeplaeff, Laura, Demais, Valérie, Sahadevan, Sonu, Hembach, Katharina M, Muller, Hans-Peter, Picchiarelli, Gina, Mishra, Nibha, Antonucci, Stefano, Dirrig-Grosch, Sylvie, Kassubek, Jan, Rasche, Volker, Ludolph, Albert, Boutillier, Anne-Laurence, Roselli, Francesco, Polymenidou, Magdalini, Lagier-Tourenne, Clotilde, Liebscher, Sabine, Dupuis, Luc

المساهمون: Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Ludwig-Maximilians University [Munich] (LMU), Universität Zürich [Zürich] = University of Zurich (UZH), Laboratoire de neurosciences cognitives et adaptatives (LNCA), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), CRBS - Centre de Recherche en Biomédecine de Strasbourg (Inserm UMS38/UNISTRA), University of Ulm (UUlm), Deutsches Zentrum für Neurodegenerative Erkrankungen [Ulm] (DZNE), German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Centre de Neurochimie, Harvard Medical School [Boston] (HMS), Harvard University [Cambridge], Munich Cluster for systems neurology [Munich] (SyNergy), Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM)-Ludwig-Maximilians-Universität München (LMU), Université de Strasbourg Inserm Faculté de médecine, Klinikum der Universitat Munchen, Ludwig-Maximilians-Universität München (LMU), University hospital of Zurich [Zurich], Universität Ulm - Ulm University [Ulm, Allemagne], Massachusetts Institute of Technology (MIT), Ludwig-Maximilians University Hospital (LMU Munich), ANR-16-CE92-0031,EpiFUS,Rôle de FUS dans la régulation des modifications épigénétiques : conséquences pour la sclérose latérale amyotrophique et la démence frontotemporale(2016), ANR-16-CE16-0015,ToFU,Interactions entre TAU, FUS et TDP-43 dans les maladies neurodégénératives(2016), ANR-19-CE17-0016,SPREADALS,Propagation et toxicité des facteurs pathogéniques de la sclérose latérale amyotrophique(2019), Technische Universität München [München] (TUM)-Ludwig-Maximilians-Universität München (LMU), Anne Laurence, Boutillier, Rôle de FUS dans la régulation des modifications épigénétiques : conséquences pour la sclérose latérale amyotrophique et la démence frontotemporale - - EpiFUS2016 - ANR-16-CE92-0031 - AAPG2016 - VALID, Interactions entre TAU, FUS et TDP-43 dans les maladies neurodégénératives - - ToFU2016 - ANR-16-CE16-0015 - AAPG2016 - VALID, Propagation et toxicité des facteurs pathogéniques de la sclérose latérale amyotrophique - - SPREADALS2019 - ANR-19-CE17-0016 - AAPG2019 - VALID, University of Zurich, Liebscher, Sabine, Dupuis, Luc, Centre de Recherche en Biomédecine de Strasbourg (CRBS), Dieterle, Stéphane

المصدر: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3028. ⟨10.1038/s41467-021-23187-9⟩
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications 12(1), 3028 (2021). doi:10.1038/s41467-021-23187-9
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-23187-9⟩
Nature Communications, 2021, 12 (1), ⟨10.1038/s41467-021-23187-9⟩
Nature Communications, 2021, 12 (1), pp.3028. ⟨10.1038/s41467-021-23187-9⟩

مصطلحات موضوعية: Male, Cytoplasm, [SDV]Life Sciences [q-bio], General Physics and Astronomy, Gene Expression, Synaptic Transmission, MESH: Synapses, Mice, MESH: Animals, Gene Knock-In Techniques, MESH: Amyotrophic Lateral Sclerosis, MESH: Gene Knock-In Techniques, metabolism [RNA-Binding Protein FUS], Motor Neurons, MESH: RNA-Binding Protein FUS, FUS protein, mouse, 3100 General Physics and Astronomy, [SDV] Life Sciences [q-bio], genetics [Amyotrophic Lateral Sclerosis], Phenotype, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Female, ddc:500, MESH: Motor Neurons, MESH: Mutation, MESH: Gene Expression, Science, 610 Medicine & health, 1600 General Chemistry, Genetics and Molecular Biology, MESH: Phenotype, Article, 1300 General Biochemistry, Genetics and Molecular Biology, MESH: Mice, Inbred C57BL, MESH: Synaptic Transmission, Animals, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], MESH: Mice, metabolism [Cytoplasm], metabolism [Amyotrophic Lateral Sclerosis], MESH: Cytoplasm, Amyotrophic Lateral Sclerosis, General Chemistry, metabolism [Motor Neurons], metabolism [Synapses], MESH: Male, Mice, Inbred C57BL, physiology [Synaptic Transmission], General Biochemistry, Mutation, Synapses, RNA-Binding Protein FUS, 11493 Department of Quantitative Biomedicine, genetics [RNA-Binding Protein FUS], MESH: Female

وصف الملف: application/pdf; 2021_NatureCummun.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c8536f94d17455134cebd44e2729e13bTest
https://www.hal.inserm.fr/inserm-03376335Test

المؤلفون: Isabelle M. Mansuy, Ali Jawaid, Magdalini Polymenidou, Niharika Gaur, Tariq Afroz, Florent Laferrière, Bisrat T. Woldemichael, Eloïse A. Kremer

المساهمون: Universität Zürich [Zürich] = University of Zurich (UZH), University of Zurich, Mansuy, Isabelle M

المصدر: Molecular Neurobiology
Molecular Neurobiology, Humana Press, 2019, 56 (5), pp.3451-3462. ⟨10.1007/s12035-018-1314-3⟩

مصطلحات موضوعية: 0301 basic medicine, Aging, 2804 Cellular and Molecular Neuroscience, Hippocampus, Smad Proteins, SMAD, 0302 clinical medicine, Amyotrophic lateral sclerosis, ComputingMilieux_MISCELLANEOUS, microRNA, Neurodegeneration, Frontotemporal lobar degeneration, 10124 Institute of Molecular Life Sciences, Neurology, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Neuroscience (miscellaneous), 610 Medicine & health, Biology, 03 medical and health sciences, Cellular and Molecular Neuroscience, TDP, Memory, Protein phosphatase 1, Cell Line, Tumor, medicine, Animals, Humans, FUS, Cell Nucleus, Memory Disorders, Environmental enrichment, 10242 Brain Research Institute, Amyotrophic Lateral Sclerosis, medicine.disease, Mice, Inbred C57BL, MicroRNAs, 030104 developmental biology, 2808 Neurology, Nerve Degeneration, RNA-Binding Protein FUS, 570 Life sciences, biology, Dementia, Frontotemporal Lobar Degeneration, Cognition Disorders, 11493 Department of Quantitative Biomedicine, Neuroscience, 030217 neurology & neurosurgery, Biogenesis

وصف الملف: Jawaid2018_MolNeurobiol.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004224d0fa7bd199ee16940f6c61344fTest
https://hal.archives-ouvertes.fr/hal-03403398Test

المؤلفون: Sandrine C. Foti, Ulrich Wagner, Florent Laferrière, Paul J. Boersema, Magdalini Polymenidou, Erwan Bezard, Marian Hruska-Plochan, Tammaryn Lashley, Amanda J Lewis, Ashraf Al-Amoudi, Francesca De Giorgi, Yasmine T. Asi, Henning Stahlberg, Larissa A. B. Gilhespy, Zuzanna Maniecka, Eva-Maria Hock, Paola Picotti, Gery Barmettler, Tariq Afroz, Adrian M. Isaacs, John Ravits, François Ichas, Manuela Pérez-Berlanga

المساهمون: Unité de recherche Virologie et Immunologie Moléculaires (VIM (UR 0892)), Institut National de la Recherche Agronomique (INRA), Universität Zürich [Zürich] = University of Zurich (UZH), Computer Vision Laboratory - ETHZ [Zurich], Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), Institute of Neurology [London], University College of London [London] (UCL), University of Basel (Unibas), Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, University of California [Davis] (UC Davis), University of California-University of California, Institut des Maladies Neurodégénératives [Bordeaux] (IMN), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), University of Zurich, Polymenidou, Magdalini, University hospital of Zurich [Zurich], UCL, Institute of Neurology [London], University of California [San Diego] (UC San Diego), University of California (UC), Laboratoire de neurosciences expérimentales et cliniques (LNEC), Université de Poitiers-Institut National de la Santé et de la Recherche Médicale (INSERM), Laferriere, Florent, University of California, Unité de recherche Virologie et Immunologie Moléculaires (VIM), University of Zürich [Zürich] (UZH), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology in Zürich [Zürich] (ETH Zürich)

المصدر: Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2019, 22 (1), pp.65-77. ⟨10.1038/s41593-018-0294-y⟩
Nature Neuroscience, 2019, 22 (1), pp.65-77. ⟨10.1038/s41593-018-0294-y⟩

مصطلحات موضوعية: 0301 basic medicine, TDP-43, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Disease duration, 610 Medicine & health, Disease, Protein aggregation, Biology, Mass Spectrometry, protein aggregation, Mice, Protein Aggregates, 03 medical and health sciences, [SCCO]Cognitive science, 0302 clinical medicine, neurotoxicity, mental disorders, medicine, Animals, Humans, Phosphorylation, Amyotrophic lateral sclerosis, Pathological, ComputingMilieux_MISCELLANEOUS, Inclusion Bodies, Neurons, prion-like seeding, General Neuroscience, [SCCO.NEUR]Cognitive science/Neuroscience, Disease progression, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Neurotoxicity, Brain, nutritional and metabolic diseases, 2800 General Neuroscience, FTD, Frontotemporal lobar degeneration, medicine.disease, nervous system diseases, DNA-Binding Proteins, HEK293 Cells, 030104 developmental biology, Disease Progression, Frontotemporal Lobar Degeneration, ALS, FTLD, Neuroscience, 11493 Department of Quantitative Biomedicine, 030217 neurology & neurosurgery

وصف الملف: 2019_Polymenidou_etal_natureNeuroscience.pdf - application/pdf; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d65522d507f8f98fb08f2c4a3944e6Test
https://hal.archives-ouvertes.fr/hal-02492708Test

المؤلفون: Dorothee Dormann, Stefan Reber, Luc Dupuis, Helena Ederle, Marian Hruska-Plochan, Eva-Maria Hock, Marc-David Ruepp, Florent Laferrière, Zuzanna Maniecka, Lucas Pelkmans, M K Sonu Sahadevan, Tammaryn Lashley, Lauren M. Gittings, Magdalini Polymenidou

المساهمون: Dieterle, Stéphane, Universität Zürich [Zürich] = University of Zurich (UZH), Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich), University of Bern, Ludwig Maximilian University [Munich] (LMU), UCL, Institute of Neurology [London], Mécanismes Centraux et Périphériques de la Neurodégénérescence, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), UK Dementia Research Institute (UK DRI), University College of London [London] (UCL), Universität Bern [Bern], Ludwig-Maximilians-Universität München (LMU), Institute of Neurology [London], King‘s College London, Universität Bern [Bern] (UNIBE), Laferriere, Florent, University of Zurich, Polymenidou, Magdalini

المصدر: Cell Reports
Cell Reports, 2018, 24 (4), pp.987-1000.e7. ⟨10.1016/j.celrep.2018.06.094⟩
Cell Reports, Elsevier Inc, 2018, 24 (4), pp.987-1000.e7. ⟨10.1016/j.celrep.2018.06.094⟩
Hock, E-M, Maniecka, Z, Hruska-Plochan, M, Reber, S, Laferrière, F, Sahadevan M K, S, Ederle, H, Gittings, L, Pelkmans, L, Dupuis, L, Lashley, T, Ruepp, M-D, Dormann, D & Polymenidou, M 2018, ' Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function ', Cell Reports, vol. 24, no. 4, pp. 987-1000.e7 . https://doi.org/10.1016/j.celrep.2018.06.094Test
Cell Reports, 24 (4)

مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, MESH: Hippocampus, Cytoplasmic inclusion, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV]Life Sciences [q-bio], MESH: Neurons, Chromosomal translocation, RNA-binding protein, RNA-binding proteins, Hippocampus, Mice, ALS, FTD, FUS, stress granules, nucleocytoplasmic shuttling, Transportin, protein aggregation, MESH: Animals, Amyotrophic lateral sclerosis, Cerebral Cortex, Neurons, Chemistry, MESH: RNA-Binding Protein FUS, Cell biology, [SDV] Life Sciences [q-bio], MESH: HEK293 Cells, Transportin 1, MESH: Cell Nucleus, 610 Medicine & health, Genetics and Molecular Biology, Karyopherins, Transfection, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Stress granule, 1300 General Biochemistry, Genetics and Molecular Biology, MESH: Mice, Inbred C57BL, medicine, Animals, Humans, MESH: Mice, Cell Nucleus, MESH: Humans, MESH: Cytoplasm, MESH: Transfection, [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, medicine.disease, MESH: Karyopherins, MESH: Cerebral Cortex, Mice, Inbred C57BL, MESH: Astrocytes, HEK293 Cells, 030104 developmental biology, Hypertonic Stress, Astrocytes, General Biochemistry, RNA-Binding Protein FUS, 11493 Department of Quantitative Biomedicine

وصف الملف: application/pdf; application/application/pdf; 1018_1-s2.0-S2211124718310362-main_checkZORA.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26cd76ee2b60a0880af6400794f15f6Test
https://doi.org/10.1016/j.celrep.2018.06.094Test