دورية أكاديمية
Outcomes of Transcatheter Aortic Valve Implantation in Nonagenarians Compared to Younger than 90 Year Old Patients
| العنوان: | Outcomes of Transcatheter Aortic Valve Implantation in Nonagenarians Compared to Younger than 90 Year Old Patients |
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| المؤلفون: | Matta, Anthony, Lhermusier, Thibault, Bouisset, Fréderic, Parada, Francisco-Campelo, Elbaz, Meyer, Nader, Vanessa, Blanco, Stephanie, Roncalli, Jerome, Carrié, Didier |
| المساهمون: | Holy-Spirit University of Kaslik Jounieh, Service Cardiologie CHU Toulouse, Pôle Cardiovasculaire et Métabolique CHU Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse) |
| المصدر: | ISSN: 0002-9343. |
| بيانات النشر: | HAL CCSD Elsevier [Commercial Publisher] |
| سنة النشر: | 2022 |
| المجموعة: | Université Toulouse III - Paul Sabatier: HAL-UPS |
| مصطلحات موضوعية: | Aortic stenosis, Nonagenarians, Outcomes, Transcatheter aortic valve implantation, MESH: Aged, 80 and over, MESH: Treatment Outcome, MESH: Aortic Valve / surgery, MESH: Aortic Valve Stenosis* / etiology, MESH: Humans, MESH: Nonagenarians, MESH: Retrospective Studies, MESH: Risk Factors, MESH: Time Factors, MESH: Transcatheter Aortic Valve Replacement* / adverse effects, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system |
| الوصف: | International audience ; Background: Given that life expectancy has improved, nonagenarians have become a significant proportion of world population. As aortic stenosis is primarily a disease of the elderly, the need for invasive cardiac approaches is expected to increase in people of extreme age. Herein, we compare the in-hospital adverse clinical outcomes and mortality after transcatheter aortic valve implantation (TAVI) procedures in nonagenarians to younger than 90 year old patients.Methods: A retrospective study was conducted on 1336 patients who underwent TAVI between January 2016 and March 2020 at Toulouse University Hospital, Rangueil, France. Post-TAVI adverse clinical outcomes were defined according to Valve Academic Research Consortium-2 Criteria. The studied population was divided into 2 groups according to age.Results: Out of 1336 patients, 250 (18.7%) were nonagenarians with a mean age of 91.8 ± 1.9 years. Pacemaker implantation (12.4% vs 12.1%), stroke (2% vs 1.8%), and major vascular complications (9.2% vs 6.7%) were more common in nonagenarians, whereas acute kidney injury (1.2% vs 2.7%) and major bleeding events (3.2% vs 3.4%) were more common in the <90-year-old group. Nonagenarians are more likely to develop major vascular complications (odds ratio [OR] = 1.76 95% confidence interval [CI] 1.04-3, P = .03). The prevalence of in-hospital mortality in nonagenarians and <90-year-old patients were 5.2% and 2%, respectively. Survival analysis showed a significant difference in mortality during hospitalization period only ( P = .04).Conclusion: The prevalence of TAVI procedural success is remarkably high in nonagenarians and comparable to that of younger patients. However, the in-hospital mortality rate was 2-fold more than that of <90-year-old patients. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/35296400; hal-04469445; https://ut3-toulouseinp.hal.science/hal-04469445Test; PUBMED: 35296400 |
| DOI: | 10.1016/j.amjmed.2022.02.024 |
| الإتاحة: | https://doi.org/10.1016/j.amjmed.2022.02.024Test https://ut3-toulouseinp.hal.science/hal-04469445Test |
| رقم الانضمام: | edsbas.1351826D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.amjmed.2022.02.024 |
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