يعرض 1 - 10 نتائج من 13 نتيجة بحث عن '"Lactate dehydrogenase"', وقت الاستعلام: 1.12s تنقيح النتائج
  1. 1

    المساهمون: Institut de Chimie et des Matériaux Paris-Est (ICMPE), Institut de Chimie du CNRS (INC)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Redox Biology
    Redox Biology, Elsevier, 2019, 20, pp.334-348. ⟨10.1016/j.redox.2018.10.020⟩
    Redox Biology, Vol 20, Iss, Pp 334-348 (2019)

    مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, Lipopolysaccharide, NQO1, NAD(P)H:quinone oxidoreductase 1, Clinical Biochemistry, Anti-Inflammatory Agents, Gene Expression, AST, aspartate aminotransferase, Pharmacology, medicine.disease_cause, Nrf2, nuclear factor erythroid 2-related factor 2, TNF-α, tumor necrosis factor-α, Biochemistry, Antioxidants, Dual-activity molecules, Mice, chemistry.chemical_compound, ARG1, arginase 1, CO-RMs, CO-releasing molecules, 0302 clinical medicine, LC-MS/MS, liquid chromatography-tandem mass spectrometry, EPF, ethyl prop-2-yn-1-yl fumarate, IL-6, interleukin-6, lcsh:QH301-705.5, Cells, Cultured, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, lcsh:R5-920, M2, anti-inflammatory macrophages, Carbon Monoxide, LDH, lactate dehydrogenase, Dimethyl fumarate, IL-10, interleukin-10, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, HMOX1, heme oxygenase-1 gene, 3. Good health, Nrf2 activators, CO, carbon monoxide, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, Cytokines, Microglia, Inflammation Mediators, medicine.symptom, lcsh:Medicine (General), Research Paper, M1, pro-inflammatory macrophages, IL-1β, interleukin-1β, NF-E2-Related Factor 2, GCLC, glutamate cysteine ligase C, Carbon monoxide (CO), Inflammation, HO-1, heme oxygenase-1 protein, GCLM, glutamate cysteine ligase M, 03 medical and health sciences, In vivo, ALT, alanine aminotransferase, medicine, Animals, [CHIM.COOR]Chemical Sciences/Coordination chemistry, ARG1, MCP-1/CCL2, monocyte chemoattractant protein-1, ALP, alkaline phosphatase, Macrophage phenotype, Activator (genetics), Macrophages, Organic Chemistry, In vitro, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, lcsh:Biology (General), chemistry, HYCOs, HYbrid CO-releasing molecules, COHb, carbonmonoxy hemoglobin, Heme Oxygenase-1, 030217 neurology & neurosurgery, Oxidative stress, Hb, hemoglobin

  2. 2

    المساهمون: Administateur, HAL Sorbonne Université, Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Department of neurology, Philipps Universität Marburg = Philipps University of Marburg, Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Department of translational neurodegeneration, German Center for Neurodegenerative Diseases, Institute of Neurogenetics, Universität zu Lübeck = University of Lübeck [Lübeck], Actelion Pharmaceuticals Ltd, Department of psychiatry, Lubeck University Hospital, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Philipps Universität Marburg, Universität zu Lübeck [Lübeck]

    المصدر: Journal of the Neurological Sciences
    Journal of the Neurological Sciences, 2015, 356 (1-2), pp.129-136. ⟨10.1016/j.jns.2015.06.030⟩
    Journal of the neurological sciences 356(1-2), 129-136 (2015). doi:10.1016/j.jns.2015.06.030
    Journal of the Neurological Sciences, Elsevier, 2015, 356 (1-2), pp.129-136. ⟨10.1016/j.jns.2015.06.030⟩

    مصطلحات موضوعية: Male, Parkinson's disease, Mitochondrial Diseases, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Cell Count, Gaucher disease, Pharmacology, metabolism [Histocompatibility Antigens], chemistry.chemical_compound, metabolism [Inositol], Mice, 0302 clinical medicine, prevention & control [Parkinsonian Disorders], Mesencephalon, pathology [Brain], Histocompatibility Antigens, Miglustat, Mitochondrial respiratory chain complex I, pharmacology [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine], analogs & derivatives [Inositol], Cells, Cultured, Neurons, 0303 health sciences, metabolism [Mesencephalon], [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, therapeutic use [1-Deoxynojirimycin], MPTP, Brain, etiology [Mitochondrial Diseases], α-Syn, 3. Good health, Mitochondria, metabolism [L-Lactate Dehydrogenase], Neurology, Biochemistry, prevention & control [Gaucher Disease], metabolism [Neurons], 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Toxicity, therapeutic use [Glycoside Hydrolase Inhibitors], drug effects [Brain], medicine.drug, Glucocerebrosidase, 1-Deoxynojirimycin, Tyrosine 3-Monooxygenase, etiology [Gaucher Disease], Glucocerebroside, conduritol epoxide, 03 medical and health sciences, Parkinsonian Disorders, complications [Parkinsonian Disorders], medicine, Animals, drug effects [Neurons], Glycoside Hydrolase Inhibitors, ddc:610, 030304 developmental biology, Alpha-synuclein, L-Lactate Dehydrogenase, drug therapy [Gaucher Disease], [SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, analogs & derivatives [1-Deoxynojirimycin], medicine.disease, Embryo, Mammalian, metabolism [Tyrosine 3-Monooxygenase], Mice, Inbred C57BL, Disease Models, Animal, chemistry, metabolism [Brain], Dopamine cell death, miglustat, Neurology (clinical), 030217 neurology & neurosurgery, Inositol, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

    وصف الملف: application/pdf

  3. 3

    المساهمون: Laboratoire de Géologie de Lyon - Terre, Planètes, Environnement [Lyon] (LGL-TPE), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-École normale supérieure - Lyon (ENS Lyon), Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601), Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS), Institut de Génomique Fonctionnelle (IGF), Université de Montpellier (UM)-Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Montpellier 2 - Sciences et Techniques (UM2)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Géologie de Lyon - Terre, Planètes, Environnement (LGL-TPE), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut national des sciences de l'Univers (INSU - CNRS)-Université Jean Monnet - Saint-Étienne (UJM)-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Université Montpellier 1 (UM1)-Université Montpellier 2 - Sciences et Techniques (UM2)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Molecular Pharmacology
    Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2012, 81 (5), pp.643-656. ⟨10.1124/mol.111.074765⟩
    Molecular Pharmacology, 2012, 81 (5), pp.643-656. ⟨10.1124/mol.111.074765⟩

    مصطلحات موضوعية: Male, CNS, central nervous system, NMDA, N-methyl-D-aspartate, mGlu, metabotropic glutamate, L-AP4, L-()-2-amino-4-phosphonobutyric acid, PHCCC, N-phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide, PPG, (R,S)-4-phosphonophenylglycine, DCG-IV, (2S,2R,3R)-2-(2,3-dicarboxycyclopropyl)glycine, ACPT-I, (1S,3R,4S)-1-aminocyclopentane-1,3,4-tricarboxylic acid, IBMX, 3-isobutyl-1-methylxanthine, MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, HEK, human embryonic kidney, InsP, inositol phosphate, DIV, days in vitro, TBS-T, Tris-buffered saline/Tween 20, LDH, lactate dehydrogenase, DA, dopamine, TH, tyrosine hydroxylase, EAE, experimental autoimmune encephalomyelitis, CSF, cerebrospinal fluid, HPLC, high-performance liquid chromatography, MS/MS, tandem mass spectrometry, LPS, lipopolysaccharide, LY379268, (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, ANOVA, analysis of variance, PLSD, protected least significant difference, DMSO, dimethyl sulfoxide, Kynurenine pathway, (2S, experimental autoimmune encephalomyelitis, Rats, Sprague-Dawley, 0302 clinical medicine, MESH: Animals, Cells, Cultured, IN-VIVO, PLSD, 0303 health sciences, ANOVA, POSITIVE ALLOSTERIC MODULATOR, CEREBELLAR GRANULE CELLS, MOLECULAR DETERMINANTS, QUINOLINIC ACID, MGLUR4 SUBTYPE, RAT-BRAIN, IN-VIVO, MICE, TRYPTOPHAN, INDUCTION, Glutamate binding, protected least significant difference, MESH: Glutamic Acid, L-()-2-amino-4-phosphonobutyric acid, 3-dicarboxycyclopropyl)glycine, dopamine, MESH: Models, Molecular, 6-tetrahydropyridine, InsP, MESH: Cells, Cultured, Agonist, LDH, mGlu, human embryonic kidney, CSF, S)-4-phosphonophenylglycine, DCG-IV, 6-dicarboxylic acid, 4-tricarboxylic acid, RAT-BRAIN, Partial agonist, cerebrospinal fluid, MGLUR4 SUBTYPE, 03 medical and health sciences, POSITIVE ALLOSTERIC MODULATOR, tandem mass spectrometry, Oxazines, MS/MS, Humans, high-performance liquid chromatography, MESH: Receptors, Metabotropic Glutamate, MPTP, Pharmacology, HEK, Tris-buffered saline/Tween 20, MESH: Humans, 6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4, TBS-T, Mice, Inbred C57BL, Metabotropic receptor, NMDA, Metabotropic glutamate receptor, (R, IBMX, HPLC, 030217 neurology & neurosurgery, Models, Molecular, 1-methyl-4-phenyl-1, DA, MESH: Kynurenine, dimethyl sulfoxide, L-AP4, MESH: Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate, N-phenyl-7-(hydroxyimino)cyclopropa[b]chromen-1a-carboxamide, 3R, tyrosine hydroxylase, Cyclic AMP, DMSO, Receptor, Kynurenine, MESH: Cyclic AMP, EAE, 3R)-2-(2, INDUCTION, lipopolysaccharide, Glutamate receptor, 2R, MOLECULAR DETERMINANTS, TRYPTOPHAN, ACPT-I, Biochemistry, QUINOLINIC ACID, TH, Molecular Medicine, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], PPG, CEREBELLAR GRANULE CELLS, CNS, analysis of variance, LPS, 5S, inositol phosphate, MESH: Rats, medicine.drug_class, Glutamic Acid, Biology, metabotropic glutamate, 4S)-1-aminocyclopentane-1, MESH: Mice, Inbred C57BL, days in vitro, medicine, Animals, MESH: Mice, 030304 developmental biology, 4R, (1R, (1S, LY379268, lactate dehydrogenase, central nervous system, DIV, MESH: Male, Rats, MICE, 3-isobutyl-1-methylxanthine, N-methyl-D-aspartate, PHCCC, MESH: Oxazines

  4. 4

    المساهمون: Department of Neurology, Philipps Universität Marburg = Philipps University of Marburg, Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Immunology, Bernhard Nocht Institute for Tropical Medicine - Bernhard-Nocht-Institut für Tropenmedizin [Hamburg, Germany] (BNITM), Institute of Neurogenetics, Universität zu Lübeck = University of Lübeck [Lübeck], Department of Psychiatry, CN was supported by a postdoctoral grant from the Deutsche Forschungsgemeinschaft, (DFG), Germany. DAF was supported by a grant from the Michael J Fox Foundation (MJFF) and from the University Medical Center Giessen and Marburg (UKGM). AO was supported by the Mildred- Scheel-Stiftung. TL was supported by a Master grant from the Fondation pour la Recherche Médicale (FRM). CH was supported by an MD thesis grant by the Boehringer Ingelheim Fond (BIF). PPM is supported by program 'Investissements d'avenir' ANR-10-IAIHU-06. ECH and SH are investigators at the Centre National pour la Recherche Scientifique (CNRS). AH was supported by a 'Poste Vert' (Accueil de Chercheurs Etrangers) from the Institut National de la Santé et de la Recherche Médicale (INSERM). The research leading to these results has received funding from the program 'Investissements d'avenir' ANR-10-IAIHU-06., BMC, Ed., Philipps Universität Marburg, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Universität zu Lübeck [Lübeck]

    المصدر: Journal of Neuroinflammation
    Journal of Neuroinflammation, 2014, 11 (1), pp.86
    Journal of Neuroinflammation, BioMed Central, 2014, 11 (1), pp.86

    وصف الملف: application/pdf

  5. 5

    المساهمون: Laboratoire de Cytophysiologie et Toxicologie Cellulaire, Université Paris Diderot - Paris 7 (UPD7), Institut Jacques Monod (IJM (UMR_7592)), Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Toxicology and Applied Pharmacology
    Toxicology and Applied Pharmacology, Elsevier, 2006, 215 (3), pp.285-94. ⟨10.1016/j.taap.2006.03.002⟩

  6. 6

    المساهمون: Northeastern University [Boston]

    المصدر: Cancer Letters
    Cancer Letters, Elsevier, 2013, 335 (1), pp.191-200. ⟨10.1016/j.canlet.2013.02.020⟩

  7. 7

    المساهمون: Institut Armand Frappier (INRS-IAF), Institut National de la Recherche Scientifique [Québec] (INRS)-Réseau International des Instituts Pasteur (RIIP), Institute of Biotechnology, VIETNAM, International Associated laboratory Samuel de Champlain, Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Recherche Scientifique [Québec] (INRS)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU), Neuroendocrinologie cellulaire et moléculaire, Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), was supported by CIHR grants (awarded to A.F.) and NSERC Discovery grant GPIN 402623-2011 (awarded to N.D.)

    المصدر: ChemBioChem
    ChemBioChem, Wiley-VCH Verlag, 2012, 13 (12), pp.1805-12. ⟨10.1002/cbic.201200081⟩

  8. 8

    المساهمون: Laboratoire de Physiopathologie et Pharmacologie Cardio-Métaboliques (U866, Lipides et nutrition, équipe 5) (LPPCM), Lipides - Nutrition - Cancer (U866) (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Ecole Nationale Supérieure de Biologie Appliquée à la Nutrition et à l'Alimentation de Dijon (ENSBANA)-Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Ecole Nationale Supérieure de Biologie Appliquée à la Nutrition et à l'Alimentation de Dijon (ENSBANA), Physiopathologie et épidémiologie cérébro-cardiovasculaire [Dijon] (PEC2), Université de Bourgogne (UB)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Vergely, Catherine

    المصدر: Cellular Physiology and Biochemistry
    Cellular Physiology and Biochemistry, 2012, 29 (3-4), pp.475-484. ⟨10.1159/000338501⟩
    Cellular Physiology and Biochemistry, Karger, 2012, 29 (3-4), pp.475-484. ⟨10.1159/000338501⟩

    وصف الملف: application/pdf

  9. 9

    المساهمون: Mycotoxines et Toxicologie Comparée des Xénobiotiques, Institut National de la Recherche Agronomique (INRA)-ISARA-Lyon-Ecole Nationale Vétérinaire de Lyon (ENVL), Ecole Nationale Vétérinaire de Lyon (ENVL)

    المصدر: Toxicology Letters
    Toxicology Letters, Elsevier, 2007, 170 (3), pp.248-258. ⟨10.1016/j.toxlet.2007.03.012⟩

  10. 10

    المساهمون: Physico-chimie, pharmacotechnie, biopharmacie (PCPB), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)

    المصدر: Biochemical Pharmacology
    Biochemical Pharmacology, Elsevier, 2006, ⟨10.1016/j.bcp.2005.11.008⟩