دورية أكاديمية
Diversity of promoter elements in a Geobacter sulfurreducens mutant adapted to disruption in electron transfer
| العنوان: | Diversity of promoter elements in a Geobacter sulfurreducens mutant adapted to disruption in electron transfer |
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| المؤلفون: | Puljic, M, Yan, B, Qu, Y, Barbe, JF, Leang, C, Krushkal, J, Lovley, DR, Adkins, RM |
| بيانات النشر: | //link.springer.de/link/service/journals/10142/index.htm Germany |
| سنة النشر: | 2009 |
| المجموعة: | University of Hong Kong: HKU Scholars Hub |
| الوصف: | The delta-proteobacterium, Geobacter sulfurreducens, can obtain energy by coupling the oxidation of organic matter to the reduction of insoluble Fe(III) or the anode of a microbial fuel cell. Because Fe(III) oxide or the anode surface, in contrast to oxygen, nitrate, or sulfate, is not soluble nor can it be reduced readily, Geobacter species have developed mechanisms which allow electrons to be delivered across outer membrane to the cell surface. OmcB is an outer-membrane c-type cytochrome important for G. sulfurreducens Fe(III) respiration. In the absence of OmcB, cells lost the ability to reduce soluble or insoluble Fe(III). However, the omcB deletion mutant can slowly adapt to growth on soluble Fe(III) over prolonged incubation in the medium with acetate as the electron donor. We discuss available information about predicted or experimentally validated promoters and transcription regulatory sites identified upstream of operons with transcriptional expression significantly changed in the adapted omcB mutant. DNA sequences of upstream regions of coregulated operons in the adapted mutant are divergent, suggesting the presence of recognition sites for different transcriptional regulators and indicating that adaptation of the omcB mutant to growth on soluble Fe(III) has shifted the relevant expression networks involved to a more diverse molecular basis. ; link_to_subscribed_fulltext |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1438-793X |
| العلاقة: | Functional & Integrative Genomics; Functional & Integrative Genomics, 2009, v. 9 n. 1, p. 15-25; 25; 15; http://hdl.handle.net/10722/210602Test |
| DOI: | 10.1007/s10142-008-0094-7 |
| الإتاحة: | https://doi.org/10.1007/s10142-008-0094-7Test http://hdl.handle.net/10722/210602Test |
| حقوق: | The final publication is available at Springer via http://dx.doi.orgTest/[insert DOI] |
| رقم الانضمام: | edsbas.14C9584E |
| قاعدة البيانات: | BASE |
| تدمد: | 1438793X |
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| DOI: | 10.1007/s10142-008-0094-7 |