دورية أكاديمية

Spontaneous resolution of acute syphilitic posterior placoid chorioretinitis: reappraisal of the literature and pathogenetic insights

التفاصيل البيبلوغرافية
العنوان: Spontaneous resolution of acute syphilitic posterior placoid chorioretinitis: reappraisal of the literature and pathogenetic insights
المؤلفون: Casalino, G, Erba, S, Sivagnanavel, V, Lari, S, Scialdone, A, Pavesio, C
المصدر: GMS Ophthalmology Cases; VOL: 10; DOC26 /20200504/
بيانات النشر: German Medical Science GMS Publishing House; Düsseldorf
سنة النشر: 2020
المجموعة: GMS e-journal - German Medical Science (Association of the Scientific Medical Societies in Germany)
مصطلحات موضوعية: acute syphilitic posterior placoid chorioretinitis, natural course, pathogenesis, retinal imaging, syphilis, ddc: 610
الوصف: Acute syphilitic posterior placoid chorioretinitis (ASPPC) is a rare clinical manifestation of ocular syphilis. Spontaneous resolution of this condition has been reported in a few cases.The aim of this manuscript is to report an additional case and to discuss the possible pathogenesis of this condition by reviewing the current evidence on this subject.A 45-year-old man presented to us with decreased vision in the right eye secondary to a placoid macular lesion. Fourteen days after presentation, there was a dramatic improvement of the vision, and multimodal retinal imaging showed almost complete spontaneous resolution of the placoid lesion. Syphilis serology turned out positive and a diagnosis of ASPPC was made. The pathogenesis of ASPPC is unclear, and there is contrasting evidence about the role of the cellular immune system. Since this condition may resolve spontaneously before systemic antimicrobial treatment, the presence of a placoid macular lesion should raise a high suspicion of ASPPC in order to make a timely diagnosis and to avoid progression of untreated syphilis.
نوع الوثيقة: article in journal/newspaper
اللغة: English
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DOI: 10.3205/oc000153
الإتاحة: https://doi.org/10.3205/oc000153Test
https://doi.org/10.1111/j.1442-9071.2010.02203.xTest
https://doi.org/10.5301/ejo.5000530Test
https://doi.org/10.3928/23258160-20141008-02Test
https://doi.org/10.1111/ceo.12679Test
https://doi.org/10.1159/000324086Test
https://doi.org/10.1016/0002-9394Test(88)90009-8
https://doi.org/10.1097/IAE.0b013e31825f3851Test
https://doi.org/10.1111/j.1600-0420.2005.00641.xTest
https://doi.org/10.3205/oc000039Test
حقوق: http://creativecommons.org/licenses/by/4.0Test/
رقم الانضمام: edsbas.8A55B0EF
قاعدة البيانات: BASE